Markus Hoth

Sustained activity of calcium release-activated calcium channels requires translocation of mitochondria to the plasma membrane.

T cell activation requires mitochondrial translocation to the immunological synapse.

Calcium dependence of T cell proliferation following focal stimulation.

Probing the redox activity of T-lymphocytes deposited at electrode surfaces with voltammetric methods.

Protein-film voltammetry: a theoretical study of the temperature effect using square-wave voltammetry.

A new rapid and simple method to determine the kinetics of electrode reactions of biologically relevant compounds from the half-peak width of the square-wave voltammograms.

The immunological synapse controls local and global calcium signals in T lymphocytes.

Efficiency of T-cell costimulation by CD80 and CD86 cross-linking correlates with calcium entry.

Differential redox regulation of ORAI ion channels: a mechanism to tune cellular calcium signaling.

Immune synapses: mitochondrial morphology matters.

Calcium binding and transport by coenzyme Q.

Docking of lytic granules at the immunological synapse in human CTL requires Vti1b-dependent pairing with CD3 endosomes.

Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation.

Redox regulation of calcium ion channels: chemical and physiological aspects.

Excitable T cells: Ca(v)1.4 channel contributions and controversies.

Pharmacology of ORAI channels as a tool to understand their physiological functions.

SNARE protein expression and localization in human cytotoxic T lymphocytes.

Molecular regulation of CRAC channels and their role in lymphocyte function.

Calcium, cancer and killing: the role of calcium in killing cancer cells by cytotoxic T lymphocytes and natural killer cells.

Hydroxylated derivatives of dimethoxy-1,4-benzoquinone as redox switchable earth-alkaline metal ligands and radical scavengers.

Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells.

The neglected CRAC proteins: Orai2, Orai3, and STIM2.

How ORAI and TRP channels interfere with each other: interaction models and examples from the immune system and the skin.

A simple, economic, time-resolved killing assay.

Measuring endogenous ICRAC and ORAI currents with the patch-clamp technique.

The minimal requirements to use calcium imaging to analyze ICRAC.

Patch-clamp measurement of ICRAC and ORAI channel activity.

Human T cells monitored by impedance spectrometry using field-effect transistor arrays: a novel tool for single-cell adhesion and migration studies.

Red fluorescent genetically encoded indicator for intracellular hydrogen peroxide.

VAMP8-dependent fusion of recycling endosomes with the plasma membrane facilitates T lymphocyte cytotoxicity.

Reversal of Mitochondrial Transhydrogenase Causes Oxidative Stress in Heart Failure.

CRAC channels, calcium, and cancer in light of the driver and passenger concept.

Deep characterization of blood cell miRNomes by NGS.

Syntaxin 8 is required for efficient lytic granule trafficking in cytotoxic T lymphocytes.

New insights into the chemistry of Coenzyme Q-0: A voltammetric and spectroscopic study.

Cytoskeleton rotation relocates mitochondria to the immunological synapse and increases calcium signals.

Optimality of Spatially Inhomogeneous Search Strategies.

DNA methylation array analysis identifies breast cancer associated RPTOR, MGRN1 and RAPSN hypomethylation in peripheral blood DNA.

The extracellular adherence protein (Eap) of Staphylococcus aureus acts as a proliferation and migration repressing factor that alters the cell morphology of keratinocytes.

Electrochemical Quantification of Extracellular Local HO Kinetics Originating from Single Cells.

Human profilin 1 is a negative regulator of CTL mediated cell-killing and migration.

NFATc1 controls the cytotoxicity of CD8 T cells.

A calcium optimum for cytotoxic T lymphocyte and natural killer cell cytotoxicity.

Quantity, quality, and functionality of peripheral blood cells derived from residual blood of different apheresis kits.