Hua Lou
Department of Genetics and Genome Sciences,
Case Comprehensive Cancer Center,
Center for RNA Science and Therapeutics
Case Western Reserve University
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U1 snRNP-dependent function of TIAR in the regulation of alternative RNA processing of the human calcitonin/CGRP pre-mRNA.
Molecular and cellular biology Sep, 2003 | Pubmed ID: 12917321
Recql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers.
Molecular and cellular biology May, 2005 | Pubmed ID: 15831450
A nuclear function of Hu proteins as neuron-specific alternative RNA processing regulators.
Molecular biology of the cell Dec, 2006 | Pubmed ID: 17035636
Role for Fox-1/Fox-2 in mediating the neuronal pathway of calcitonin/calcitonin gene-related peptide alternative RNA processing.
Molecular and cellular biology Feb, 2007 | Pubmed ID: 17101796
Hu proteins regulate polyadenylation by blocking sites containing U-rich sequences.
The Journal of biological chemistry Jan, 2007 | Pubmed ID: 17127772
Regulation of neuron-specific alternative splicing of neurofibromatosis type 1 pre-mRNA.
Molecular and cellular biology Feb, 2008 | Pubmed ID: 18086893
Repression of prespliceosome complex formation at two distinct steps by Fox-1/Fox-2 proteins.
Molecular and cellular biology Sep, 2008 | Pubmed ID: 18573872
The neurofibromatosis type I pre-mRNA is a novel target of CELF protein-mediated splicing regulation.
Nucleic acids research Jan, 2010 | Pubmed ID: 19854948
Promotion of exon 6 inclusion in HuD pre-mRNA by Hu protein family members.
Nucleic acids research Jun, 2010 | Pubmed ID: 20159993
RECQL5 is an important determinant for camptothecin tolerance in human colorectal cancer cells.
Bioscience reports Oct, 2011 | Pubmed ID: 21210765
Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2011 | Pubmed ID: 21808035
Alternative splicing of the neurofibromatosis type I pre-mRNA.
Bioscience reports Apr, 2012 | Pubmed ID: 22115364
Depolarization-mediated regulation of alternative splicing.
Frontiers in neuroscience , 2011 | Pubmed ID: 22207834
Alternative splicing of the neurofibromatosis type 1 pre-mRNA is regulated by the muscleblind-like proteins and the CUG-BP and ELAV-like factors.
BMC molecular biology Dec, 2012 | Pubmed ID: 23227900
All three RNA recognition motifs and the hinge region of HuC play distinct roles in the regulation of alternative splicing.
Nucleic acids research May, 2013 | Pubmed ID: 23525460
The p97-UBXD8 complex destabilizes mRNA by promoting release of ubiquitinated HuR from mRNP.
Genes & development May, 2013 | Pubmed ID: 23618873
Regulation of alternative splicing by local histone modifications: potential roles for RNA-guided mechanisms.
Nucleic acids research Jan, 2014 | Pubmed ID: 24081581
Neurofibromatosis type 1 alternative splicing is a key regulator of Ras signaling in neurons.
Molecular and cellular biology Jun, 2014 | Pubmed ID: 24710274
Calcium-mediated histone modifications regulate alternative splicing in cardiomyocytes.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2014 | Pubmed ID: 25368158
A journey.
RNA (New York, N.Y.) Apr, 2015 | Pubmed ID: 25780189
Histone hyperacetylation and exon skipping: a calcium-mediated dynamic regulation in cardiomyocytes.
Nucleus (Austin, Tex.) , 2015 | Pubmed ID: 26325491
In Vitro Analysis of Ribonucleoprotein Complex Remodeling and Disassembly.
Methods in molecular biology (Clifton, N.J.) , 2016 | Pubmed ID: 26965258
Reconstitution of HuR-Inhibited CUGBP1 Expression Protects Cardiomyocytes from Acute Myocardial Infarction-Induced Injury.
Antioxidants & redox signaling Nov, 2017 | Pubmed ID: 28350193
Neurofibromatosis type 1 alternative splicing is a key regulator of Ras/ERK signaling and learning behaviors in mice.
Human molecular genetics 10, 2017 | Pubmed ID: 28934393
A new bioluminescent imaging technology for studying oxidative stress in the testis and its impacts on fertility.
Free radical biology & medicine Aug, 2018 | Pubmed ID: 29803806
Quantitative Analysis of Alternative Pre-mRNA Splicing in Mouse Brain Sections Using RNA In Situ Hybridization Assay
1Department of Genetics and Genome Sciences, Case Western Reserve University,
2Department of Endocrinology, Dongfang Hospital of Beijing University of Chinese Medicine,
3Case Comprehensive Cancer Center, Case Western Reserve University,
4Center for RNA Science and Therapeutics, Case Western Reserve University
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