Moores Cancer Center,
Department of Surgery,
Division of Surgical Oncology
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Incidence, natural history, and patterns of locoregional recurrence in gastric cancer patients treated with preoperative chemoradiotherapy.
International journal of radiation oncology, biology, physics Jul, 2008 | Pubmed ID: 18164837
Neoadjuvant therapy for pancreatic cancer.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract Sep, 2008 | Pubmed ID: 18259825
Beyond the ivory tower: outcomes following surgery for ampullary cancer.
Annals of surgical oncology Jul, 2008 | Pubmed ID: 18425553
Case report: focal nesidioblastosis ("nesidioblastoma") in an adult.
Human pathology Mar, 2010 | Pubmed ID: 20004945
Silencing of RON receptor signaling promotes apoptosis and gemcitabine sensitivity in pancreatic cancers.
Cancer research Feb, 2010 | Pubmed ID: 20103639
Pancreatic cancer: preface.
Surgical oncology clinics of North America Apr, 2010 | Pubmed ID: 20159512
Cystic neoplasms of the pancreas.
Surgical oncology clinics of North America Apr, 2010 | Pubmed ID: 20159515
The RON tyrosine kinase receptor regulates vascular endothelial growth factor production in pancreatic cancer cells.
Pancreas Apr, 2010 | Pubmed ID: 20358644
Development of an orthotopic model of invasive pancreatic cancer in an immunocompetent murine host.
Clinical cancer research : an official journal of the American Association for Cancer Research Jul, 2010 | Pubmed ID: 20534740
IGF1-R signals through the RON receptor to mediate pancreatic cancer cell migration.
Carcinogenesis Aug, 2011 | Pubmed ID: 21565828
Disruption of p16 and activation of Kras in pancreas increase ductal adenocarcinoma formation and metastasis in vivo.
Oncotarget Nov, 2011 | Pubmed ID: 22113502
The RON-receptor regulates pancreatic cancer cell migration through phosphorylation-dependent breakdown of the hemidesmosome.
International journal of cancer Oct, 2012 | Pubmed ID: 22275185
Chemokine CXCL12 activates dual CXCR4 and CXCR7-mediated signaling pathways in pancreatic cancer cells.
Journal of translational medicine Apr, 2012 | Pubmed ID: 22472349
Changing the way we do business: recommendations to accelerate biomarker development in pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Feb, 2013 | Pubmed ID: 23344262
Borderline resectable pancreatic cancer: need for standardization and methods for optimal clinical trial design.
Annals of surgical oncology Aug, 2013 | Pubmed ID: 23435609
Therapeutic advances in pancreatic cancer.
Gastroenterology Jun, 2013 | Pubmed ID: 23622141
A dual-color genetically engineered mouse model for multispectral imaging of the pancreatic microenvironment.
Pancreas Aug, 2013 | Pubmed ID: 23648841
PI3Kα activates integrin α4β1 to establish a metastatic niche in lymph nodes.
Proceedings of the National Academy of Sciences of the United States of America May, 2013 | Pubmed ID: 23671068
Improved perioperative outcomes with minimally invasive distal pancreatectomy: results from a population-based analysis.
JAMA surgery Mar, 2014 | Pubmed ID: 24402232
Generation of orthotopic patient-derived xenografts from gastrointestinal stromal tumor.
Journal of translational medicine Feb, 2014 | Pubmed ID: 24507750
The RON receptor tyrosine kinase in pancreatic cancer pathogenesis and its potential implications for future targeted therapies.
Pancreas Mar, 2014 | Pubmed ID: 24518495
Single-incision laparoscopic surgery through an ostomy site: a natural approach by an unnatural orifice.
Surgical laparoscopy, endoscopy & percutaneous techniques Feb, 2015 | Pubmed ID: 24743670
An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.
Nature cell biology May, 2014 | Pubmed ID: 24747441
Genome-wide mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin.
Genome medicine , 2014 | Pubmed ID: 24944587
Dual blockade of epidermal growth factor receptor and insulin-like growth factor receptor-1 signaling in metastatic pancreatic cancer: phase Ib and randomized phase II trial of gemcitabine, erlotinib, and cixutumumab versus gemcitabine plus erlotinib (SWOG S0727).
Cancer Oct, 2014 | Pubmed ID: 25041791
Predictors of progression in high-grade appendiceal or colorectal peritoneal carcinomatosis after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
Annals of surgical oncology May, 2015 | Pubmed ID: 25145504
Borderline resectable pancreatic cancer: definitions and management.
World journal of gastroenterology Aug, 2014 | Pubmed ID: 25152577
Long-term outcomes after total pancreatectomy and islet cell autotransplantation: is it a durable operation?
Annals of surgery Oct, 2014 | Pubmed ID: 25203883
Correction: Genome-wide mutational landscape of mucinous carcinomatosis peritonei of appendiceal origin.
Genome medicine , 2014 | Pubmed ID: 25228923
A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic cancer.
Cancer research Nov, 2014 | Pubmed ID: 25261239
A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.
Nature medicine Nov, 2014 | Pubmed ID: 25326799
Enteral stenting for gastric outlet obstruction and afferent limb syndrome following pancreaticoduodenectomy.
Annals of gastroenterology , 2014 | Pubmed ID: 25332208
Tumor-penetrating iRGD peptide inhibits metastasis.
Molecular cancer therapeutics Jan, 2015 | Pubmed ID: 25392370
Laparoscopic evacuation of mucinous ascites for palliation of pseudomyxoma peritonei.
Annals of surgical oncology May, 2015 | Pubmed ID: 25395145
Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery.
Cancer research Apr, 2015 | Pubmed ID: 25681274
BAP1 mutation is a frequent somatic event in peritoneal malignant mesothelioma.
Journal of translational medicine Apr, 2015 | Pubmed ID: 25889843
Approach to patients with pancreatic cancer without detectable metastases.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Jun, 2015 | Pubmed ID: 25918279
SWOG S0809: A Phase II Intergroup Trial of Adjuvant Capecitabine and Gemcitabine Followed by Radiotherapy and Concurrent Capecitabine in Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Aug, 2015 | Pubmed ID: 25964250
A tumor-penetrating peptide enhances circulation-independent targeting of peritoneal carcinomatosis.
Journal of controlled release : official journal of the Controlled Release Society Aug, 2015 | Pubmed ID: 26071630
A novel protein isoform of the RON tyrosine kinase receptor transforms human pancreatic duct epithelial cells.
Oncogene Jun, 2016 | Pubmed ID: 26477314
Laparoscopy is Safe and Accurate to Evaluate Peritoneal Surface Metastasis Prior to Cytoreductive Surgery.
Annals of surgical oncology May, 2016 | Pubmed ID: 26542584
A Novel Tool for Predicting Major Complications After Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy.
Annals of surgical oncology May, 2016 | Pubmed ID: 26678406
FRAX597, a PAK1 inhibitor, synergistically reduces pancreatic cancer growth when combined with gemcitabine.
BMC cancer Jan, 2016 | Pubmed ID: 26774265
Urokinase-controlled tumor penetrating peptide.
Journal of controlled release : official journal of the Controlled Release Society 06, 2016 | Pubmed ID: 27106816
Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression.
Cancer discovery Aug, 2016 | Pubmed ID: 27179037
Preoperative Modified FOLFIRINOX Treatment Followed by Capecitabine-Based Chemoradiation for Borderline Resectable Pancreatic Cancer: Alliance for Clinical Trials in Oncology Trial A021101.
JAMA surgery Aug, 2016 | Pubmed ID: 27275632
Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.
Nature 06, 2016 | Pubmed ID: 27281208
Characterization of RON protein isoforms in pancreatic cancer: implications for biology and therapeutics.
Oncotarget Jul, 2016 | Pubmed ID: 27323855
Safety and Outcome Measures of First-in-Human Intraperitoneal α Radioimmunotherapy With 212Pb-TCMC-Trastuzumab.
American journal of clinical oncology Jul, 2018 | Pubmed ID: 27906723
Effect of Selumetinib and MK-2206 vs Oxaliplatin and Fluorouracil in Patients With Metastatic Pancreatic Cancer After Prior Therapy: SWOG S1115 Study Randomized Clinical Trial.
JAMA oncology Apr, 2017 | Pubmed ID: 27978579
Hyaluronan-binding peptide for targeting peritoneal carcinomatosis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine May, 2017 | Pubmed ID: 28468593
Overinterpretation is common in pathological diagnosis of appendix cancer during patient referral for oncologic care.
PloS one , 2017 | Pubmed ID: 28591173
Molecular Pathways: Targeting the Microenvironment of Liver Metastases.
Clinical cancer research : an official journal of the American Association for Cancer Research Nov, 2017 | Pubmed ID: 28615370
An Intergroup Randomized Phase II Study of Bevacizumab or Cetuximab in Combination with Gemcitabine and in Combination with Chemoradiation in Patients with Resected Pancreatic Carcinoma: A Trial of the ECOG-ACRIN Cancer Research Group (E2204).
Oncology , 2018 | Pubmed ID: 29040974
Factors Associated with 60-Day Readmission Following Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy.
Annals of surgical oncology Jan, 2018 | Pubmed ID: 29090402
GPR68, a proton-sensing GPCR, mediates interaction of cancer-associated fibroblasts and cancer cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Mar, 2018 | Pubmed ID: 29092903
Reprogramming pancreatic stellate cells via p53 activation: A putative target for pancreatic cancer therapy.
PloS one , 2017 | Pubmed ID: 29211796
Histologic Predictors of Recurrence in Mucinous Appendiceal Tumors with Peritoneal Dissemination after HIPEC.
Annals of surgical oncology Mar, 2018 | Pubmed ID: 29282599
Cirrhosis is not a contraindication to cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in highly selected patients.
World journal of surgical oncology Apr, 2018 | Pubmed ID: 29699564
GPCRomics: GPCR Expression in Cancer Cells and Tumors Identifies New, Potential Biomarkers and Therapeutic Targets.
Frontiers in pharmacology , 2018 | Pubmed ID: 29872392
Preoperative Circulating Tumor DNA in Patients with Peritoneal Carcinomatosis is an Independent Predictor of Progression-Free Survival.
Annals of surgical oncology Aug, 2018 | Pubmed ID: 29948422
E47 Governs the MYC-CDKN1B/p27-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16 and Wild-Type p53.
Cellular and molecular gastroenterology and hepatology , 2018 | Pubmed ID: 30003124
Does Primary Tumor Side Matter in Patients with Metastatic Colon Cancer Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy?
Annals of surgical oncology May, 2019 | Pubmed ID: 30815802
Exosomes from Pancreatic Juice: A Step Closer to the Holy Grail?
Annals of surgical oncology Jul, 2019 | Pubmed ID: 30820788
Inhibition of invasive pancreatic cancer: restoring cell apoptosis by activating mitochondrial p53.
American journal of cancer research , 2019 | Pubmed ID: 30906636
A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma.
Cell Apr, 2019 | Pubmed ID: 30955884
MST1R kinase accelerates pancreatic cancer progression via effects on both epithelial cells and macrophages.
Oncogene 07, 2019 | Pubmed ID: 30967626
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.
Nature 05, 2019 | Pubmed ID: 30996350
Primary Tumor Sidedness is Predictive of Survival in Colon Cancer Patients Treated with Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy: A US HIPEC Collaborative Study.
Annals of surgical oncology Jul, 2019 | Pubmed ID: 31016486
Incidence, Risk Factors, and Prevention Strategies for Venous Thromboembolism after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy.
Annals of surgical oncology Jul, 2019 | Pubmed ID: 31065960
Obstruction-Free Survival Following Operative Intervention for Malignant Bowel Obstruction in Appendiceal Cancer.
Annals of surgical oncology Oct, 2019 | Pubmed ID: 31190209
Optimal Surveillance Frequency After CRS/HIPEC for Appendiceal and Colorectal Neoplasms: A Multi-institutional Analysis of the US HIPEC Collaborative.
Annals of surgical oncology Jan, 2020 | Pubmed ID: 31243668
Association of an acute pain service with postoperative outcomes following pancreaticoduodenectomy.
Journal of perioperative practice Oct, 2019 | Pubmed ID: 31524066
Precision Chemoradiotherapy for HER2 Tumors Using Antibody Conjugates of an Auristatin Derivative with Reduced Cell Permeability.
Molecular cancer therapeutics Jan, 2020 | Pubmed ID: 31597712
Detection and Quantification of GPCR mRNA: An Assessment and Implications of Data from High-Content Methods.
ACS omega Oct, 2019 | Pubmed ID: 31646252
Adherence with operative standards in the treatment of gastric cancer in the United States.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association May, 2020 | Pubmed ID: 31745679
Institutional variation in recovery after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: An opportunity for enhanced recovery pathways.
Journal of surgical oncology Oct, 2020 | Pubmed ID: 32627199
Surgical Outcome Results From SWOG S1505: A Randomized Clinical Trial of mFOLFIRINOX Versus Gemcitabine/Nab-paclitaxel for Perioperative Treatment of Resectable Pancreatic Ductal Adenocarcinoma.
Annals of surgery Sep, 2020 | Pubmed ID: 32740235
Prognostic Utility of Pre- and Postoperative Circulating Tumor DNA Liquid Biopsies in Patients with Peritoneal Metastases.
Annals of surgical oncology Sep, 2020 | Pubmed ID: 32767050
Preoperative bevacizumab does not increase complications following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
PloS one , 2020 | Pubmed ID: 33270763
A Multi-institutional Study of Peritoneal Recurrence Following Resection of Low-grade Appendiceal Mucinous Neoplasms.
Annals of surgical oncology Aug, 2021 | Pubmed ID: 33415564
A MET Targeting Antibody-Drug Conjugate Overcomes Gemcitabine Resistance in Pancreatic Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research Apr, 2021 | Pubmed ID: 33451980
Efficacy of Perioperative Chemotherapy for Resectable Pancreatic Adenocarcinoma: A Phase 2 Randomized Clinical Trial.
JAMA oncology Mar, 2021 | Pubmed ID: 33475684
Phase I Trial of Stereotactic Body Radiation Therapy Dose Escalation in Pancreatic Cancer.
International journal of radiation oncology, biology, physics Jul, 2021 | Pubmed ID: 33571625
Macropinocytosis in Cancer-Associated Fibroblasts Is Dependent on CaMKK2/ARHGEF2 Signaling and Functions to Support Tumor and Stromal Cell Fitness.
Cancer discovery Jul, 2021 | Pubmed ID: 33653692
Predictors and significance of histologic response to neoadjuvant therapy for gastric cancer.
Journal of surgical oncology May, 2021 | Pubmed ID: 33735448
Clinical Data Prediction Model to Identify Patients With Early-Stage Pancreatic Cancer.
JCO clinical cancer informatics Mar, 2021 | Pubmed ID: 33739856
Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis.
Cancer cell May, 2021 | Pubmed ID: 33740421
Tumor-penetrating therapy for β5 integrin-rich pancreas cancer.
Nature communications Mar, 2021 | Pubmed ID: 33750829
Ki67 does not predict recurrence for low-grade appendiceal mucinous neoplasms with peritoneal dissemination after cytoreductive surgery and HIPEC.
Human pathology Jul, 2021 | Pubmed ID: 33905776
Tri-modal management of primary small cell carcinoma of the pancreas (SCCP): a rare neuroendocrine carcinoma (NEC).
BMC gastroenterology Sep, 2021 | Pubmed ID: 34479480
Randomized Phase II Study of PARP Inhibitor ABT-888 (Veliparib) with Modified FOLFIRI versus FOLFIRI as Second-line Treatment of Metastatic Pancreatic Cancer: SWOG S1513.
Clinical cancer research : an official journal of the American Association for Cancer Research Dec, 2021 | Pubmed ID: 34580114
Using Organotypic Tissue Slices to Investigate the Microenvironment of Pancreatic Cancer: Pharmacotyping and Beyond.
Cancers Oct, 2021 | Pubmed ID: 34638476
Author Correction: Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.
Nature Dec, 2021 | Pubmed ID: 34848876
Establishment of Patient-Derived Pancreatic Cancer Organoids from Endoscopic Ultrasound-Guided Fine-Needle Aspiration Biopsies.
Gut and liver Jul, 2022 | Pubmed ID: 34916338
Fluorescent Anti-MUC5AC Brightly Targets Pancreatic Cancer in a Patient-derived Orthotopic Xenograft.
In vivo (Athens, Greece) , 2022 | Pubmed ID: 34972700
The MST1R/RON Tyrosine Kinase in Cancer: Oncogenic Functions and Therapeutic Strategies.
Cancers Apr, 2022 | Pubmed ID: 35454943
Early-stage multi-cancer detection using an extracellular vesicle protein-based blood test.
Communications medicine , 2022 | Pubmed ID: 35603292
An Ex Vivo Organotypic Culture Platform for Functional Interrogation of Human Appendiceal Cancer Reveals a Prominent and Heterogenous Immunological Landscape.
Clinical cancer research : an official journal of the American Association for Cancer Research Nov, 2022 | Pubmed ID: 36067351
Alvimopan for Enhanced Gastrointestinal Recovery after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Randomized Controlled Trial.
Journal of the American College of Surgeons Nov, 2022 | Pubmed ID: 36102565
Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome.
Nature Oct, 2022 | Pubmed ID: 36198801
Is Routine Omentectomy a Necessary Component of Cytoreductive Surgery and HIPEC?
Annals of surgical oncology Oct, 2022 | Pubmed ID: 36305990
ASO Visual Abstract: Is Routine Omentectomy a Necessary Component of Cytoreductive Surgery and HIPEC?
Annals of surgical oncology Nov, 2022 | Pubmed ID: 36369408
Laparoscopic cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a prospective clinical trial and comparative analysis.
Surgical endoscopy Dec, 2022 | Pubmed ID: 36477643
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