Baofeng Yang

Pilocarpine modulates the cellular electrical properties of mammalian hearts by activating a cardiac M3 receptor and a K+ current.

The effect of arsenic trioxide on QT interval prolongation during APL therapy.

Potential mechanisms for the enhancement of HERG K+ channel function by phospholipid metabolites.

Purification and characterization of the human erythrocyte band 3 protein C-terminal domain.

Protein tyrosine kinase is expressed and regulates ROMK1 location in the cortical collecting duct.

MicroRNAs and atrial fibrillation: mechanisms and translational potential.

ROMK1 channel activity is regulated by monoubiquitination.

[Inhibitory effect of potential metastasis in SGC-7901 cells induced by beta-ionone].

Choline produces cytoprotective effects against ischemic myocardial injuries: evidence for the role of cardiac m3 subtype muscarinic acetylcholine receptors.

Resveratrol, a natural ingredient of grape skin: antiarrhythmic efficacy and ionic mechanisms.

Ischemia impairs the association between connexin 43 and M3 subtype of acetylcholine muscarinic receptor (M3-mAChR) in ventricular myocytes.

Effects of replacing the unreliable cDNA microarray measurements on the disease classification based on gene expression profiles and functional modules.

alpha-Tocopheryl succinate-induced apoptosis in human gastric cancer cells is modulated by ERK1/2 and c-Jun N-terminal kinase in a biphasic manner.

Effects of Cilazapril on atrial electrical, structural and functional remodeling in atrial fibrillation dogs.

Various tolerances to arsenic trioxide between human cortical neurons and leukemic cells.

Inhibitory effects of artemisinin on voltage-gated ion channels in intact nodose ganglion neurones of adult rats.

The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2.

Large-conductance Ca2+-activated K+ currents blocked and impaired by homocysteine in human and rat mesenteric artery smooth muscle cells.

Adenosine stimulates the basolateral 50 pS K channels in the thick ascending limb of the rat kidney.

Effects of polyamines on apoptosis induced by simulated ischemia/reperfusion injury in cultured neonatal rat cardiomyocytes.

PGE2 inhibits apical K channels in the CCD through activation of the MAPK pathway.

The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes.

Flavonoids from Chinese Viscum coloratum produce cytoprotective effects against ischemic myocardial injuries: inhibitory effect of flavonoids on PAF-induced Ca2+ overload.

Phospholipid lysophosphatidylcholine as a metabolic trigger and HERG as an ionic pathway for extracellular K accumulation and "short QT syndrome" in acute myocardial ischemia.

Sphingolipid metabolite ceramide causes metabolic perturbation contributing to HERG K+ channel dysfunction.

Gaining confidence in biological interpretation of the microarray data: the functional consistence of the significant GO categories.

K restriction inhibits protein phosphatase 2B (PP2B) and suppression of PP2B decreases ROMK channel activity in the CCD.

Arsenic trioxide-induced apoptosis in H9c2 cardiomyocytes: implications in cardiotoxicity.

miRNAs at the heart of the matter.

Role of siRNA silencing of MMP-2 gene on invasion and growth of laryngeal squamous cell carcinoma.

JAK/STAT and PI3K/AKT pathways form a mutual transactivation loop and afford resistance to oxidative stress-induced apoptosis in cardiomyocytes.

Characterization and comparison of Na+, K+ and Ca2+ currents between myocytes from human atrial right appendage and atrial septum.

PGE2 inhibits basolateral 50 pS potassium channels in the thick ascending limb of the rat kidney.

Inhibition on LS-174T cell growth and activity of telomerase in vitro and in vivo by arsenic trioxide.

Control of cardiac excitability by microRNAs.

Constructing disease-specific gene networks using pair-wise relevance metric: application to colon cancer identifies interleukin 8, desmin and enolase 1 as the central elements.

Aberration of L-type calcium channel in cardiac myocytes is one of the mechanisms of arrhythmia induced by cerebral ischemia.

Scutellarin-induced endothelium-independent relaxation in rat aorta.

Antiangiogenic effect of capecitabine combined with ginsenoside Rg3 on breast cancer in mice.

Inhibition of laryngeal cancer cell invasion and growth with lentiviral-vector delivered short hairpin RNA targeting human MMP-9 gene.

Homocysteine modulates sodium channel currents in human atrial myocytes.

A single anti-microRNA antisense oligodeoxyribonucleotide (AMO) targeting multiple microRNAs offers an improved approach for microRNA interference.

Differential effect of imatinib and synergism of combination treatment with chemotherapeutic agents in malignant glioma cells.

Related transcriptional enhancer factor-1 induces fibroblast growth factor receptor-1 expression in endothelial cells.

Bone marrow mesenchymal stem cells upregulate transient outward potassium currents in postnatal rat ventricular myocytes.

Can pancreatic duct-derived progenitors be a source of islet regeneration?

MicroRNA-1 downregulation by propranolol in a rat model of myocardial infarction: a new mechanism for ischaemic cardioprotection.

The protective effect of Daming capsule on heart function in streptozocin-induced diabetic rats with hyperlipidemia.

Bezafibrate induces myotoxicity in human rhabdomyosarcoma cells via peroxisome proliferator-activated receptor alpha signaling.

Antiarrhythmic properties of long-term treatment with matrine in arrhythmic rat induced by coronary ligation.

Tanshinone IIA protects against sudden cardiac death induced by lethal arrhythmias via repression of microRNA-1.

Circulating microRNA-1 as a potential novel biomarker for acute myocardial infarction.

Calcium-sensing receptors induce apoptosis in rat cardiomyocytes via the endo(sarco)plasmic reticulum pathway during hypoxia/reoxygenation.

Activation of cardiac muscarinic M3 receptors induces delayed cardioprotection by preserving phosphorylated connexin43 and up-regulating cyclooxygenase-2 expression.

Mechanism of impaired baroreflex sensitivity in Wistar rats fed a high-fat and -carbohydrate diet.

Evaluation of (99)  (m)TcN-MPO as a new myocardial perfusion imaging agent in normal dogs and in an acute myocardial infarction canine model: comparison with (99)  (m)Tc-sestamibi.

Arsenic trioxide promotes mitochondrial DNA mutation and cell apoptosis in primary APL cells and NB4 cell line.

Cerebral ischemia elicits aberration in myocardium contractile function and intracellular calcium handling.

Scutellarin alleviates interstitial fibrosis and cardiac dysfunction of infarct rats by inhibiting TGFβ1 expression and activation of p38-MAPK and ERK1/2.

MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation.

L-type calcium current (ICa,L) and inward rectifier potassium current (IK1) are involved in QT prolongation induced by arsenic trioxide in rat.

Tanshinone IIA inhibits miR-1 expression through p38 MAPK signal pathway in post-infarction rat cardiomyocytes.

The same chromosome 9p21.3 locus is associated with type 2 diabetes and coronary artery disease in a Chinese Han population.

Tanshinone IIA protects against cardiac hypertrophy via inhibiting calcineurin/NFATc3 pathway.

Difference of sodium currents between pediatric and adult human atrial myocytes: evidence for developmental changes of sodium channels.

Transcriptional and post-transcriptional mechanisms for oncogenic overexpression of ether à go-go K+ channel.

MiR-106a inhibits glioma cell growth by targeting E2F1 independent of p53 status.

Calcium-sensing receptor activating phosphorylation of PKCδ translocation on mitochondria to induce cardiomyocyte apoptosis during ischemia/reperfusion.

Overexpression of M₃ muscarinic receptor is a novel strategy for preventing sudden cardiac death in transgenic mice.

TGFBR3, a potential negative regulator of TGF-β signaling, protects cardiac fibroblasts from hypoxia-induced apoptosis.

Activation of β(3)-adrenoceptor promotes rapid pacing-induced atrial electrical remodeling in rabbits.

Post-conditioning protecting rat cardiomyocytes from apoptosis via attenuating calcium-sensing receptor-induced endo(sarco)plasmic reticulum stress.

Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1α-mediated TRPC signalling.

Homocysteine enhances clot-promoting activity of endothelial cells via phosphatidylserine externalization and microparticles formation.

Bioactivity-guided fractionation of the triglyceride-lowering component and in vivo and in vitro evaluation of hypolipidemic effects of Calyx seu Fructus Physalis.

Daming capsule restores endothelial dysfunction induced by high-fat diet.

MicroRNA-101 inhibited postinfarct cardiac fibrosis and improved left ventricular compliance via the FBJ osteosarcoma oncogene/transforming growth factor-β1 pathway.

Arsenic-induced interstitial myocardial fibrosis reveals a new insight into drug-induced long QT syndrome.

Upregulation of microRNA-1 and microRNA-133 contributes to arsenic-induced cardiac electrical remodeling.

A novel reciprocal loop between microRNA-21 and TGFβRIII is involved in cardiac fibrosis.

Arsenic trioxide-induced hERG K(+) channel deficiency can be rescued by matrine and oxymatrine through up-regulating transcription factor Sp1 expression.

Advance in research of microRNA in Caenorhabditis elegans.

miR-1 Exacerbates Cardiac Ischemia-Reperfusion Injury in Mouse Models.

Gadd45α: a novel diabetes-associated gene potentially linking diabetic cardiomyopathy and baroreflex dysfunction.

Arsenic trioxide induces cardiac fibroblast apoptosis in vitro and in vivo by up-regulating TGF-β1 expression.

MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation.

Overexpression of microRNA-1 Causes Atrioventricular Block in Rodents.

Downregulation of miR-133 via MAPK/ERK signaling pathway involved in nicotine-induced cardiomyocyte apoptosis.

β3-adrenoceptor mediates metabolic protein remodeling in a rabbit model of tachypacing-induced atrial fibrillation.

OPN gene polymorphism and the serum OPN levels confer the susceptibility and prognosis of ischemic stroke in Chinese patients.

MicroRNA regulation and cardiac calcium signaling: role in cardiac disease and therapeutic potential.

Over-expression of hypoxia-inducible factor-1 alpha in vitro protects the cardiac fibroblasts from hypoxia-induced apoptosis.

The antifibrotic effects and mechanisms of microRNA-26a action in idiopathic pulmonary fibrosis.

MicroRNA-328 as a regulator of cardiac hypertrophy.

Berberine hydrochloride prevents postsurgery intestinal adhesion and inflammation in rats.

let-7e replacement yields potent anti-arrhythmic efficacy via targeting beta 1-adrenergic receptor in rat heart.

Arsenic trioxide and mannitol for the treatment of acute promyelocytic leukemia relapse in the central nervous system.

MicroRNA-23a mediates mitochondrial compromise in estrogen deficiency-induced concentric remodeling via targeting PGC-1α.

miR-101 promotes breast cancer cell apoptosis by targeting Janus kinase 2.

Berberine induces hERG channel deficiency through trafficking inhibition.

Genistein alleviates pressure overload-induced cardiac dysfunction and interstitial fibrosis in mice.

Expression profile of long non-coding RNAs in a mouse model of cardiac hypertrophy.

MicroRNA-1 aggravates cardiac oxidative stress by post-transcriptional modification of the antioxidant network.

MicroRNA-26a prevents endothelial cell apoptosis by directly targeting TRPC6 in the setting of atherosclerosis.

MicroRNA-30c contributes to the development of hypoxia pulmonary hypertension by inhibiting platelet-derived growth factor receptor β expression.

Downregulation of miR-21 is involved in direct actions of ursolic acid on the heart: implications for cardiac fibrosis and hypertrophy.

Mesenchymal Stem Cells and Cardiomyocytes Interplay to Prevent Myocardial Hypertrophy.

Acetyl salicylic acid attenuates cardiac hypertrophy through Wnt signaling.

Chinese innovation in cardiovascular drug discovery.

miR-183 regulates autophagy and apoptosis in colorectal cancer through targeting of UVRAG.

Jujuboside B Reduces Vascular Tension by Increasing Ca2+ Influx and Activating Endothelial Nitric Oxide Synthase.

Reciprocal Changes of Circulating Long Non-Coding RNAs ZFAS1 and CDR1AS Predict Acute Myocardial Infarction.

Long noncoding RNA H19 mediates melatonin inhibition of premature senescence of c-kit(+) cardiac progenitor cells by promoting miR-675.

MicroRNA-300 inhibited glioblastoma progression through ROCK1.

MiR-223-3p as a Novel MicroRNA Regulator of Expression of Voltage-Gated K+ Channel Kv4.2 in Acute Myocardial Infarction.

miR-106a promotes cardiac hypertrophy by targeting mitofusin 2.

Endothelial to mesenchymal transition contributes to arsenic-trioxide-induced cardiac fibrosis.

Pyroptosis is involved in the pathogenesis of human hepatocellular carcinoma.

The anti-hyperglycemic efficacy of a lipid-lowering drug Daming capsule and the underlying signaling mechanisms in a rat model of diabetes mellitus.

Caveolin proteins: a molecular insight into disease.

Manipulating PML SUMOylation via Silencing UBC9 and RNF4 Regulates Cardiac Fibrosis.

MIAT Is a Pro-fibrotic Long Non-coding RNA Governing Cardiac Fibrosis in Post-infarct Myocardium.

Over-expression of microRNA-1 causes arrhythmia by disturbing intracellular trafficking system.

Identification and Functional Verification of MicroRNAs in the Obese Rat With Erectile Dysfunction.

Melatonin prevents endothelial cell pyroptosis via regulation of long noncoding RNA MEG3/miR-223/NLRP3 axis.

Downregulation of Long Non-Coding RNA Kcnq1ot1: An Important Mechanism of Arsenic Trioxide-Induced Long QT Syndrome.

Pneumonic plague epidemic in Northeast China in 1910-1911: Dr. Wu Lien-Teh's epidemic preventive system for plague control.

Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis.

Low-Intensity Pulsed Ultrasound Prevents the Oxidative Stress Induced Endothelial-Mesenchymal Transition in Human Aortic Endothelial Cells.

LncRNA PFL contributes to cardiac fibrosis by acting as a competing endogenous RNA of let-7d.

LncRNA as a SERCA2a Inhibitor to Cause Intracellular Ca Overload and Contractile Dysfunction in a Mouse Model of Myocardial Infarction.

Abnormal Downregulation of Caveolin-3 Mediates the Pro-Fibrotic Action of MicroRNA-22 in a Model of Myocardial Infarction.

PEP06 polypeptide 30 exerts antitumour effect in colorectal carcinoma via inhibiting epithelial-mesenchymal transition.

Long non-coding RNA Gm2199 rescues liver injury and promotes hepatocyte proliferation through the upregulation of ERK1/2.

Apoptosis-inducing effects and growth inhibitory of a novel chalcone, in human hepatic cancer cells and lung cancer cells.

A LC-MS/MS method to monitor the concentration of HYD-PEP06, a RGD-modified Endostar mimetic peptide in rat blood.

SNX17 produces anti-arrhythmic effects by preserving functional SERCA2a protein in myocardial infarction.

Overexpression of miR-135b attenuates pathological cardiac hypertrophy by targeting CACNA1C.

The Long Noncoding RNA CAREL Controls Cardiac Regeneration.

MicroRNA-17 impairs glucose metabolism in insulin-resistant skeletal muscle via repressing glucose transporter 4 expression.

Long non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling.

Heme oxygenase-1 prevents heart against myocardial infarction by attenuating ischemic injury-induced cardiomyocytes senescence.

Emodin improves glucose metabolism by targeting microRNA-20b in insulin-resistant skeletal muscle.

4-Alkyl-5,7-dihydroxycoumarins from the flowering buds of Mesua ferrea.

Increase of late sodium current contributes to enhanced susceptibility to atrial fibrillation in diabetic mice.

Long non-coding RNAs as new regulators of cardiac electrophysiology and arrhythmias: Molecular mechanisms, therapeutic implications and challenges.

Emodin alleviates cardiac fibrosis by suppressing activation of cardiac fibroblasts upregulating metastasis associated protein 3.

Daming capsule, a hypolipidaemic drug, lowers blood lipids by activating the AMPK signalling pathway.

SIRT6-mediated transcriptional suppression of MALAT1 is a key mechanism for endothelial to mesenchymal transition.

Long Noncoding RNA-DACH1 (Dachshund Homolog 1) Regulates Cardiac Function by Inhibiting SERCA2a (Sarcoplasmic Reticulum Calcium ATPase 2a).

Systematic Analysis of Intestinal MicroRNAs Expression in HCC: Identification of Suitable Reference Genes in Fecal Samples.

Long non-coding RNA cardiac hypertrophy-associated regulator governs cardiac hypertrophy via regulating miR-20b and the downstream PTEN/AKT pathway.

Kanglexin, a novel anthraquinone compound, protects against myocardial ischemic injury in mice by suppressing NLRP3 and pyroptosis.

Anthocyanidin attenuates myocardial ischemia induced injury via inhibition of ROS-JNK-Bcl-2 pathway: New mechanism of anthocyanidin action.

PEP06 polypeptide 30 is a novel cluster-dissociating agent inhibiting v integrin/FAK/Src signaling in oral squamous cell carcinoma cells.

MiR-135b protects cardiomyocytes from infarction through restraining the NLRP3/caspase-1/IL-1β pathway.

Fibroblast growth factor 21 inhibited ischemic arrhythmias via targeting miR-143/EGR1 axis.

Targeting LncDACH1 promotes cardiac repair and regeneration after myocardium infarction.