Oliver Bogler

Studying the heterogeneity of brain tumors using medium throughput LOH analysis.

A novel seven transmembrane receptor induced during the early steps of astrocyte differentiation identified by differential expression.

Apoptosis in gliomas, and its role in their current and future treatment.

The proliferation marker pKi-67 organizes the nucleolus during the cell cycle depending on Ran and cyclin B.

Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization.

SETA/CIN85/Ruk and its binding partner AIP1 associate with diverse cytoskeletal elements, including FAKs, and modulate cell adhesion.

Angiogenesis in glioma: molecular mechanisms and roadblocks to translation.

Meningiomas: analysis of loss of heterozygosity on chromosome 10 in tumor progression and the delineation of four regions of chromosomal deletion in common with other cancers.

Meningiomas: loss of heterozygosity on chromosome 10 and marker-specific correlations with grade, recurrence, and survival.

p53-mediated repression of DNA methyltransferase 1 expression by specific DNA binding.

Constitutive EGFR signaling confers a motile phenotype to neural stem cells.

Proliferation marker pKi-67 occurs in different isoforms with various cellular effects.

Alix/AIP1 antagonizes epidermal growth factor receptor downregulation by the Cbl-SETA/CIN85 complex.

Studying protein isoforms of the adaptor SETA/CIN85/Ruk with monoclonal antibodies.

Src phosphorylation of Alix/AIP1 modulates its interaction with binding partners and antagonizes its activities.

Analysis of glioma cell platinum response by metacomparison of two-dimensional chromatographic proteome profiles.

Angiogenesis and apoptosis in glioma: two arenas for promising new therapies.

Polynuclear platinum anticancer drugs are more potent than cisplatin and induce cell cycle arrest in glioma.

Mutations within the kinase domain and truncations of the epidermal growth factor receptor are rare events in bladder cancer: implications for therapy.

Phosphorylation of the proline-rich domain of Xp95 modulates Xp95 interaction with partner proteins.

Proteomic comparison of oligodendrogliomas with and without 1pLOH.

Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3.

Biomarkers and cancer stem cells in primary brain tumors. Foreword.

Proteomics: the new frontier also for brain tumor research.

Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells.

Exploratory analysis of the copy number alterations in glioblastoma multiforme.

Stage-specific effect of inhibition of autophagy on chemotherapy-induced cytotoxicity.

Human bone marrow-derived mesenchymal stem cells for intravascular delivery of oncolytic adenovirus Delta24-RGD to human gliomas.

Combined action of the dinuclear platinum compound BBR3610 with the PI3-K inhibitor PX-866 in glioblastoma.

CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice.

The polynuclear platinum BBR3610 induces G2/M arrest and autophagy early and apoptosis late in glioma cells.

Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma.

Analysis of phosphotyrosine signaling in glioblastoma identifies STAT5 as a novel downstream target of ΔEGFR.

Forced dimerization increases the activity of ΔEGFR/EGFRvIII and enhances its oncogenicity.

Inhibition of Wnt signaling by cucurbitacin B in breast cancer cells: reduction of Wnt-associated proteins and reduced translocation of galectin-3-mediated β-catenin to the nucleus.

Restoring soluble guanylyl cyclase expression and function blocks the aggressive course of glioma.

Nuclear EGFRvIII-STAT5b complex contributes to glioblastoma cell survival by direct activation of the Bcl-XL promoter.

Signal transducer and activator of transcription 3 promotes angiogenesis and drives malignant progression in glioma.

Regulation of HGF expression by ΔEGFR-mediated c-Met activation in glioblastoma cells.

Signal transducer and activator of transcription 5b drives malignant progression in a PDGFB-dependent proneural glioma model by suppressing apoptosis.

Suppression of RAF/MEK or PI3K synergizes cytotoxicity of receptor tyrosine kinase inhibitors in glioma tumor-initiating cells.

mA Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program.