Emmanuel Lesuisse

A comparative study of iron uptake mechanisms in marine microalgae: iron binding at the cell surface is a critical step.

The basis for evolution of DNA-binding specificity of the Aft1 transcription factor in yeasts.

Overexpression of the yeast frataxin homolog (Yfh1): contrasting effects on iron-sulfur cluster assembly, heme synthesis and resistance to oxidative stress.

KlAft, the Kluyveromyces lactis ortholog of Aft1 and Aft2, mediates activation of iron-responsive transcription through the PuCACCC Aft-type sequence.

Evidence that yeast frataxin is not an iron storage protein in vivo.

Frataxin and mitochondrial FeS cluster biogenesis.

Nonreductive iron uptake mechanism in the marine alveolate Chromera velia.

Co-precipitation of phosphate and iron limits mitochondrial phosphate availability in Saccharomyces cerevisiae lacking the yeast frataxin homologue (YFH1).

Gex1 is a yeast glutathione exchanger that interferes with pH and redox homeostasis.

Rim2, a pyrimidine nucleotide exchanger, is needed for iron utilization in mitochondria.

Mutation in the Fe-S scaffold protein Isu bypasses frataxin deletion.

The yeast metacaspase is implicated in oxidative stress response in frataxin-deficient cells.

Human mitochondrial ferritin improves respiratory function in yeast mutants deficient in iron-sulfur cluster biogenesis, but is not a functional homologue of yeast frataxin.

Different iron sources to study the physiology and biochemistry of iron metabolism in marine micro-algae.

Giardia intestinalis incorporates heme into cytosolic cytochrome b₅.

A novel protein, ubiquitous in marine phytoplankton, concentrates iron at the cell surface and facilitates uptake.

A Yeast/Drosophila Screen to Identify New Compounds Overcoming Frataxin Deficiency.

Central role for ferritin in the day/night regulation of iron homeostasis in marine phytoplankton.

Ostreococcus tauri is a new model green alga for studying iron metabolism in eukaryotic phytoplankton.

Acclimation of a low iron adapted Ostreococcus strain to iron limitation through cell biomass lowering.

Quantitative proteomics in Friedreich's ataxia B-lymphocytes: A valuable approach to decipher the biochemical events responsible for pathogenesis.

Endocytosis-mediated siderophore uptake as a strategy for Fe acquisition in diatoms.

The adaptive response to iron involves changes in energetic strategies in the pathogen Candida albicans.