Barbara Rothen-Rutishauser

Investigating the interaction of cellulose nanofibers derived from cotton with a sophisticated 3D human lung cell coculture.

Interaction and localization of synthetic nanoparticles in healthy and cystic fibrosis airway epithelial cells: effect of ozone exposure.

Surfactant Protein D modulates allergen particle uptake and inflammatory response in a human epithelial airway model.

Nanoparticles and cells: an interdisciplinary approach.

Pulmonary surfactant coating of multi-walled carbon nanotubes (MWCNTs) influences their oxidative and pro-inflammatory potential in vitro.

Effects of flame made zinc oxide particles in human lung cells - a comparison of aerosol and suspension exposures.

Cerium dioxide nanoparticles can interfere with the associated cellular mechanistic response to diesel exhaust exposure.

Can the Ames test provide an insight into nano-object mutagenicity? Investigating the interaction between nano-objects and bacteria.

Surface charge of polymer coated SPIONs influences the serum protein adsorption, colloidal stability and subsequent cell interaction in vitro.

Gold nanorods: controlling their surface chemistry and complete detoxification by a two-step place exchange.

Nanomaterials and the human lung: what is known and what must be deciphered to realise their potential advantages?

Exposure of silver-nanoparticles and silver-ions to lung cells in vitro at the air-liquid interface.

Quantification of gold nanoparticle cell uptake under controlled biological conditions and adequate resolution.

Studying the oxidative stress paradigm in vitro: a theoretical and practical perspective.

Bioavailability of silver nanoparticles and ions: from a chemical and biochemical perspective.

Fate of TLR-1/TLR-2 agonist functionalised pDNA nanoparticles upon deposition at the human bronchial epithelium in vitro.

A comparative study of different in vitro lung cell culture systems to assess the most beneficial tool for screening the potential adverse effects of carbon nanotubes.

Fluorescence-encoded gold nanoparticles: library design and modulation of cellular uptake into dendritic cells.

Insertion of nanoparticle clusters into vesicle bilayers.

Test-methods on the test-bench: a comparison of complete exhaust and exhaust particle extracts for genotoxicity/mutagenicity assessment.

Modeling nanoparticle-alveolar epithelial cell interactions under breathing conditions using captive bubble surfactometry.

Effects of an iron-based fuel-borne catalyst and a diesel particle filter on exhaust toxicity in lung cells in vitro.

State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology.

Size-dependent accumulation of particles in lysosomes modulates dendritic cell function through impaired antigen degradation.

An in vitro testing strategy towards mimicking the inhalation of high aspect ratio nanoparticles.

Mimicking exposures to acute and lifetime concentrations of inhaled silver nanoparticles by two different in vitro approaches.

In vitro interaction of colloidal nanoparticles with mammalian cells: What have we learned thus far?

Thermally reversible self-assembly of nanoparticles via polymer crystallization.

Quantification of nanoparticles at the single-cell level: an overview about state-of-the-art techniques and their limitations.

Different endocytotic uptake mechanisms for nanoparticles in epithelial cells and macrophages.

Uptake efficiency of surface modified gold nanoparticles does not correlate with functional changes and cytokine secretion in human dendritic cells in vitro.

Engineering an in vitro air-blood barrier by 3D bioprinting.

Repeated exposure to carbon nanotube-based aerosols does not affect the functional properties of a 3D human epithelial airway model.

A biological perspective toward the interaction of theranostic nanoparticles with the bloodstream - what needs to be considered?

Biomimetics of fetal alveolar flow phenomena using microfluidics.

Fate of cellulose nanocrystal aerosols deposited on the lung cell surface in vitro.

Avoiding drying-artifacts in transmission electron microscopy: Characterizing the size and colloidal state of nanoparticles.

Nanoparticle colloidal stability in cell culture media and impact on cellular interactions.

Plasmonic nanoparticles and their characterization in physiological fluids.

Translocation of gold nanoparticles across the lung epithelial tissue barrier: Combining in vitro and in silico methods to substitute in vivo experiments.

Investigating the role of shape on the biological impact of gold nanoparticles in vitro.

Assessment of a panel of interleukin-8 reporter lung epithelial cell lines to monitor the pro-inflammatory response following zinc oxide nanoparticle exposure under different cell culture conditions.

Directed cell growth in multi-zonal scaffolds for cartilage tissue engineering.

Ultrathin Ceramic Membranes as Scaffolds for Functional Cell Coculture Models on a Biomimetic Scale.

Articular cartilage: from formation to tissue engineering.

Engineered nanomaterials: toward effective safety management in research laboratories.

Pulmonary delivery of cationic gold nanoparticles boost antigen-specific CD4 T Cell Proliferation.

Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials.

Diesel exhaust: current knowledge of adverse effects and underlying cellular mechanisms.

Predicting pulmonary fibrosis in humans after exposure to multi-walled carbon nanotubes (MWCNTs).

Current in vitro approaches to assess nanoparticle interactions with lung cells.

Hazard identification of exhausts from gasoline-ethanol fuel blends using a multi-cellular human lung model.

Identification and Characterization of a Dendritic Cell Precursor in Parenchymal Lung Tissue.

Combined exposure of diesel exhaust particles and respirable Soufrière Hills volcanic ash causes a (pro-)inflammatory response in an in vitro multicellular epithelial tissue barrier model.

Interaction of biomedical nanoparticles with the pulmonary immune system.

Organometallic cobalamin anticancer derivatives for targeted prodrug delivery via transcobalamin-mediated uptake.

A rapid screening method to evaluate the impact of nanoparticles on macrophages.

A novel technique to determine the cell type specific response within an in vitro co-culture model via multi-colour flow cytometry.

Assumption-free morphological quantification of single anisotropic nanoparticles and aggregates.

Quantifying nanoparticle cellular uptake: which method is best?

Human Asthmatic Bronchial Cells Are More Susceptible to Subchronic Repeated Exposures of Aerosolized Carbon Nanotubes At Occupationally Relevant Doses Than Healthy Cells.

Biokinetics of Aerosolized Liposomal Ciclosporin A in Human Lung Cells In Vitro Using an Air-Liquid Cell Interface Exposure System.

Exposure to silver nanoparticles affects viability and function of natural killer cells, mostly via the release of ions.

Assessing the Stability of Fluorescently Encoded Nanoparticles in Lysosomes by Using Complementary Methods.

Characteristics and properties of nano-LiCoO synthesized by pre-organized single source precursors: Li-ion diffusivity, electrochemistry and biological assessment.

Effects of gasoline and ethanol-gasoline exhaust exposure on human bronchial epithelial and natural killer cells in vitro.

A Fast and Reliable Method for Screening of Exhaust Emission Toxicity in Lung Cells.

Hybrid Lipid/Polymer Nanoparticles for Pulmonary Delivery of siRNA: Development and Fate Upon In Vitro Deposition on the Human Epithelial Airway Barrier.

Biodistribution of single and aggregated gold nanoparticles exposed to the human lung epithelial tissue barrier at the air-liquid interface.

Assessment of lung cell toxicity of various gasoline engine exhausts using a versatile in vitro exposure system.

Nanoparticle-Cell Interaction: A Cell Mechanics Perspective.

Biodistribution, Clearance, and Long-Term Fate of Clinically Relevant Nanomaterials.

Respiratory hazard assessment of combined exposure to complete gasoline exhaust and respirable volcanic ash in a multicellular human lung model at the air-liquid interface.

A realistic in vitro exposure revealed seasonal differences in (pro-)inflammatory effects from ambient air in Fribourg, Switzerland.

Probing nano-scale viscoelastic response in air and in liquid with dynamic atomic force microscopy.

Biological response of an in vitro human 3D lung cell model exposed to brake wear debris varies based on brake pad formulation.

Acute effects of multi-walled carbon nanotubes on primary bronchial epithelial cells from COPD patients.

Distribution of polymer-coated gold nanoparticles in a 3D lung model and indication of apoptosis after repeated exposure.

A novel sample holder for 4D live cell imaging to study cellular dynamics in complex 3D tissue cultures.

Subcellular Imaging of Liquid Silicone Coated-Intestinal Epithelial Cells.

Mimicking the Chemistry of Natural Eumelanin Synthesis: The KE Sequence in Polypeptides and in Proteins Allows for a Specific Control of Nanosized Functional Polydopamine Formation.

A rational and iterative process for targeted nanoparticle design and validation.

Carbon nanodots: Opportunities and limitations to study their biodistribution at the human lung epithelial tissue barrier.

Publisher Correction: Subcellular Imaging of Liquid Silicone Coated-Intestinal Epithelial Cells.

The crux of positive controls - Pro-inflammatory responses in lung cell models.

Revealing the Role of Epithelial Mechanics and Macrophage Clearance during Pulmonary Epithelial Injury Recovery in the Presence of Carbon Nanotubes.

Polydopamine/Transferrin Hybrid Nanoparticles for Targeted Cell-Killing.

Emergence of Nanoplastic in the Environment and Possible Impact on Human Health.

A Simple Method to Determine Cytotoxicity of Water-Soluble Organic Compounds and Solid Particles from Biomass Combustion in Lung Cells in Vitro.

Polymer-Coated Gold Nanospheres Do Not Impair the Innate Immune Function of Human B Lymphocytes in Vitro.

A hydrofluoric acid-free method to dissolve and quantify silica nanoparticles in aqueous and solid matrices.

Precision of Taylor Dispersion.

On the issue of transparency and reproducibility in nanomedicine.

Reduction of Nanoparticle Load in Cells by Mitosis but Not Exocytosis.

Publisher Correction: On the issue of transparency and reproducibility in nanomedicine.

Targeting specific membranes with an azide derivative of the pore-forming peptide ceratotoxin A.

Publisher Correction: On the issue of transparency and reproducibility in nanomedicine.

Assessment of the potential for in-plume sulphur dioxide gas-ash interactions to influence the respiratory toxicity of volcanic ash.

Mimicking cigarette smoke exposure to assess cutaneous toxicity.

Lipid nanoparticles biocompatibility and cellular uptake in a 3D human lung model.

Understanding the assembly of amphiphilic additives in bulk and dispersed non-lamellar lipid-based matrices: Phosphorylation, H-bonding and ionisation.

Resolution Limit of Taylor Dispersion: An Exact Theoretical Study.

Quantification of Carbon Nanotube Doses in Adherent Cell Culture Assays Using UV-VIS-NIR Spectroscopy.

Corrigendum to "The crux of positive controls - Pro-inflammatory responses in lung cell models" [Toxicology in Vitro 54 (2019) 189-193].

Versatile Macroscale Concentration Gradients of Nanoparticles in Soft Nanocomposites.

Innovative preclinical models for pulmonary drug delivery research.

Use of EpiAlveolar Lung Model to Predict Fibrotic Potential of Multiwalled Carbon Nanotubes.

Bioprinting for Human Respiratory and Gastrointestinal In Vitro Models.

From Bioinspired Glue to Medicine: Polydopamine as a Biomedical Material.

A novel 3D intestine barrier model to study the immune response upon exposure to microplastics.

Characterization of the Shape Anisotropy of Superparamagnetic Iron Oxide Nanoparticles during Thermal Decomposition.

Cytotoxicity of Mn-based photoCORMs of ethynyl-α-diimine ligands against different cancer cell lines: The key role of CO-depleted metal fragments.

Impact of airborne particulate matter on skin: a systematic review from epidemiology to in vitro studies.

An In Vitro Lung System to Assess the Proinflammatory Hazard of Carbon Nanotube Aerosols.

Reducing Aerosol-Related Risk of Transmission in the Era of COVID-19: An Interim Guidance Endorsed by the International Society of Aerosols in Medicine.

Rapid and sensitive quantification of cell-associated multi-walled carbon nanotubes.

When plants and plastic interact.

Increased Uptake of Silica Nanoparticles in Inflamed Macrophages but Not upon Co-Exposure to Micron-Sized Particles.

Air-Liquid Interface Models for Respiratory Toxicology Research: Consensus Workshop and Recommendations.

An Inflamed Human Alveolar Model for Testing the Efficiency of Anti-inflammatory Drugs .

Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis.

Bench approaches to study the detrimental cutaneous impact of tropospheric ozone.

Patient-derived and artificial ascites have minor effects on MeT-5A mesothelial cells and do not facilitate ovarian cancer cell adhesion.

Silica nanoparticles enhance disease resistance in Arabidopsis plants.

Particle Stiffness and Surface Topography Determine Macrophage-Mediated Removal of Surface Adsorbed Particles.

Understanding the Development, Standardization, and Validation Process of Alternative In Vitro Test Methods for Regulatory Approval from a Researcher Perspective.

Non-Animal Strategies for Toxicity Assessment of Nanoscale Materials: Role of Adverse Outcome Pathways in the Selection of Endpoints.

Design of Perfused PTFE Vessel-Like Constructs for In Vitro Applications.

Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine.

Inter-laboratory variability of A549 epithelial cells grown under submerged and air-liquid interface conditions.

Detection of Sub-Micro- and Nanoplastic Particles on Gold Nanoparticle-Based Substrates through Surface-Enhanced Raman Scattering (SERS) Spectroscopy.