School of Medicine
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Biosensor detection of triplex formation by modified oligonucleotides.
Analytical biochemistry Aug, 2002 | Pubmed ID: 12202239
Apoptosis in leukemia cells is accompanied by alterations in the levels and localization of nucleolin.
The Journal of biological chemistry Mar, 2003 | Pubmed ID: 12506112
Biophysical and biological properties of quadruplex oligodeoxyribonucleotides.
Nucleic acids research Apr, 2003 | Pubmed ID: 12682360
Bis-anthracycline antibiotics inhibit human immunodeficiency virus type 1 transcription.
Antimicrobial agents and chemotherapy May, 2004 | Pubmed ID: 15105117
AGRO100 inhibits activation of nuclear factor-kappaB (NF-kappaB) by forming a complex with NF-kappaB essential modulator (NEMO) and nucleolin.
Molecular cancer therapeutics Jul, 2006 | Pubmed ID: 16891465
Quartets in G-major. The First International Meeting on Quadruplex DNA.
EMBO reports Nov, 2007 | Pubmed ID: 17901879
AS1411 alters the localization of a complex containing protein arginine methyltransferase 5 and nucleolin.
Cancer research Nov, 2007 | Pubmed ID: 17974993
Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer.
Experimental and molecular pathology Jun, 2009 | Pubmed ID: 19454272
G-rich oligonucleotides for cancer treatment.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19565914
Cytotoxic and anti-infective sesquiterpenes present in Plagiochila disticha (Plagiochilaceae) and Ambrosia peruviana (Asteraceae).
Planta medica May, 2010 | Pubmed ID: 19960415
Cancer-selective antiproliferative activity is a general property of some G-rich oligodeoxynucleotides.
Nucleic acids research Mar, 2010 | Pubmed ID: 20008101
Resolution and characterization of the structural polymorphism of a single quadruplex-forming sequence.
Nucleic acids research Aug, 2010 | Pubmed ID: 20348136
Solution structure of the RBD1,2 domains from human nucleolin.
Journal of biomolecular NMR May, 2010 | Pubmed ID: 20376532
A new paradigm for aptamer therapeutic AS1411 action: uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanism.
Cancer research Nov, 2010 | Pubmed ID: 20861190
Physangulidines A, B, and C: three new antiproliferative withanolides from Physalis angulata L.
Organic letters Mar, 2012 | Pubmed ID: 22329497
Identification and characterization of nucleolin as a COUP-TFII coactivator of retinoic acid receptor β transcription in breast cancer cells.
PloS one , 2012 | Pubmed ID: 22693611
Physangulidine A, a withanolide from Physalis angulata, perturbs the cell cycle and induces cell death by apoptosis in prostate cancer cells.
Journal of natural products Jan, 2013 | Pubmed ID: 23270478
A novel small molecule that induces oxidative stress and selectively kills malignant cells.
Free radical biology & medicine Mar, 2014 | Pubmed ID: 24321317
Aptamer imaging with Cu-64 labeled AS1411: preliminary assessment in lung cancer.
Nuclear medicine and biology Feb, 2014 | Pubmed ID: 24373858
Mechanistic studies of anticancer aptamer AS1411 reveal a novel role for nucleolin in regulating Rac1 activation.
Molecular oncology Aug, 2015 | Pubmed ID: 25911416
AS1411-conjugated gold nanospheres and their potential for breast cancer therapy.
Oncotarget Sep, 2015 | Pubmed ID: 26045302
G-quadruplex oligonucleotide AS1411 as a cancer-targeting agent: Uses and mechanisms.
Biochimica et biophysica acta. General subjects May, 2017 | Pubmed ID: 28007579
Plagiochiline A Inhibits Cytokinetic Abscission and Induces Cell Death.
Molecules (Basel, Switzerland) Jun, 2018 | Pubmed ID: 29895732
Targeted Gold Nanoparticle⁻Oligonucleotide Contrast Agents in Combination with a New Local Voxel-Wise MRI Analysis Algorithm for In Vitro Imaging of Triple-Negative Breast Cancer.
Nanomaterials (Basel, Switzerland) May, 2019 | Pubmed ID: 31067749
Characterizing Oligonucleotide Uptake in Cultured Cells: A Case Study Using AS1411 Aptamer.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 31410797
Synthesis, Characterization, and Biological Activity of Hybrid Thiosemicarbazone-Alkylthiocarbamate Metal Complexes.
Inorganic chemistry Apr, 2020 | Pubmed ID: 32159342
Delivery of thymoquinone to cancer cells with as1411-conjugated nanodroplets.
PloS one , 2020 | Pubmed ID: 32437399
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