Inna N. Lavrik

The chains of death: a new view on caspase-8 activation at the DISC.

Mathematical modeling of apoptosis.

Quantification of High-Molecular Weight Protein Platforms by AQUA Mass Spectrometry as Exemplified for the CD95 Death-Inducing Signaling Complex (DISC).

Quantification of CD95-induced apoptosis and NF-κB activation at the single cell level.

Quantification of apoptosis and necroptosis at the single cell level by a combination of Imaging Flow Cytometry with classical Annexin V/propidium iodide staining.

Combinatorial treatment of CD95L and gemcitabine in pancreatic cancer cells induces apoptotic and RIP1-mediated necroptotic cell death network.

Mosaic gene network modelling identified new regulatory mechanisms in HCV infection.

Prediction of tissue-specific effects of gene knockout on apoptosis in different anatomical structures of human brain.

Parameter identification using stochastic simulations reveals a robustness in CD95 apoptotic response.

NACE: A web-based tool for prediction of intercompartmental efficiency of human molecular genetic networks.

A study of structural properties of gene network graphs for mathematical modeling of integrated mosaic gene networks.

Post-translational Modification of Caspases: The Other Side of Apoptosis Regulation.

A guide to automated apoptosis detection: How to make sense of imaging flow cytometry data.

Alterations in the nucleocytoplasmic transport in apoptosis: Caspases lead the way.

Caspase-2 is a negative regulator of necroptosis.

Prioritization of genes involved in endothelial cell apoptosis by their implication in lymphedema using an analysis of associative gene networks with ANDSystem.

Decoding the sweet regulation of apoptosis: the role of glycosylation and galectins in apoptotic signaling pathways.

Modulation of CD95-mediated signaling by post-translational modifications: towards understanding CD95 signaling networks.

Long and short isoforms of c-FLIP act as control checkpoints of DED filament assembly.

Delineating the role of c-FLIP/NEMO interaction in the CD95 network via rational design of molecular probes.

Dissecting DISC regulation via pharmacological targeting of caspase-8/c-FLIP heterodimer.

Controlling Cell Death through Post-translational Modifications of DED Proteins.

YB-1 Mediates TNF-Induced Pro-Survival Signaling by Regulating NF-κB Activation.

Pharmacological targeting of c-FLIP and Bcl-2 family members promotes apoptosis in CD95L-resistant cells.