Paul S. Freemont

Synthetic biology industry: data-driven design is creating new opportunities in biotechnology.

Bacillus subtilis YngB contributes to wall teichoic acid glucosylation and glycolipid formation during anaerobic growth.

Motions and negative cooperativity between p97 domains revealed by cryo-electron microscopy and quantised elastic deformational model.

Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47.

Conformational changes in the AAA ATPase p97-p47 adaptor complex.

Cd36, a class B scavenger receptor, functions as a monomer to bind acetylated and oxidized low-density lipoproteins.

AAA proteins and the life process.

Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS.

Specialization of an Exonuclease III family enzyme in the repair of 3' DNA lesions during base excision repair in the human pathogen Neisseria meningitidis.

Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.

Validation of an entirely in vitro approach for rapid prototyping of DNA regulatory elements for synthetic biology.

The p97-FAF1 protein complex reveals a common mode of p97 adaptor binding.

Structural and mechanistic insight into the Listeria monocytogenes two-enzyme lipoteichoic acid synthesis system.

Coevolution of the ATPase ClpV, the sheath proteins TssB and TssC, and the accessory protein TagJ/HsiE1 distinguishes type VI secretion classes.

Complex structure and biochemical characterization of the Staphylococcus aureus cyclic diadenylate monophosphate (c-di-AMP)-binding protein PstA, the founding member of a new signal transduction protein family.

New quantitative approaches reveal the spatial preference of nuclear compartments in mammalian fibroblasts.

Delineation of metabolic gene clusters in plant genomes by chromatin signatures.

EcoFlex: A Multifunctional MoClo Kit for E. coli Synthetic Biology.

TssA forms a gp6-like ring attached to the type VI secretion sheath.

Development of a Bacillus subtilis cell-free transcription-translation system for prototyping regulatory elements.

Computational protein design with backbone plasticity.

Inhibitor Selectivity for Cyclin-Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study.

Streptomyces venezuelae TX-TL - a next generation cell-free synthetic biology tool.

With all due respect to Maholo, lab automation isn't anthropomorphic.

Cell-free synthetic biology for prototype engineering.

The AAA+ ATPase p97, a cellular multitool.

Atomic Structure of Type VI Contractile Sheath from Pseudomonas aeruginosa.

Rapid acquisition and model-based analysis of cell-free transcription-translation reactions from nonmodel bacteria.

EcoFlex: A Multifunctional MoClo Kit for E. coli Synthetic Biology.

Building a global alliance of biofoundries.

Author Correction: Building a global alliance of biofoundries.

A Biosynthetic Platform for Antimalarial Drug Discovery.

A role for Biofoundries in rapid development and validation of automated SARS-CoV-2 clinical diagnostics.

Author Correction: A role for Biofoundries in rapid development and validation of automated SARS-CoV-2 clinical diagnostics.

Combinatorial metabolic pathway assembly approaches and toolkits for modular assembly.

A Cell-Free Toolkit for Synthetic Biology.

Refactoring of a synthetic raspberry ketone pathway with EcoFlex.

Correction to: Refactoring of a synthetic raspberry ketone pathway with EcoFlex.