Gerard A. Ateshian

A Conewise Linear Elasticity mixture model for the analysis of tension-compression nonlinearity in articular cartilage.

The functional environment of chondrocytes within cartilage subjected to compressive loading: a theoretical and experimental approach.

An automated approach for direct measurement of two-dimensional strain distributions within articular cartilage under unconfined compression.

Influence of seeding density and dynamic deformational loading on the developing structure/function relationships of chondrocyte-seeded agarose hydrogels.

Computer simulations of patellofemoral joint surgery. Patient-specific models for tuberosity transfer.

Optical determination of anisotropic material properties of bovine articular cartilage in compression.

Codominance of the individual posterior cruciate ligament bundles. An analysis of bundle lengths and orientation.

Experimental verification of the roles of intrinsic matrix viscoelasticity and tension-compression nonlinearity in the biphasic response of cartilage.

Sequential wear patterns of the articular cartilage of the thumb carpometacarpal joint in osteoarthritis.

Synergistic action of growth factors and dynamic loading for articular cartilage tissue engineering.

Radiography and visual pathology of the osteoarthritic scaphotrapezio-trapezoidal joint, and its relationship to trapeziometacarpal osteoarthritis.

Cartilage interstitial fluid load support in unconfined compression.

Anatomically shaped osteochondral constructs for articular cartilage repair.

Inhomogeneous cartilage properties enhance superficial interstitial fluid support and frictional properties, but do not provide a homogeneous state of stress.

Hydrostatic pressurization and depletion of trapped lubricant pool during creep contact of a rippled indenter against a biphasic articular cartilage layer.

Modeling of neutral solute transport in a dynamically loaded porous permeable gel: implications for articular cartilage biosynthesis and tissue engineering.

The correspondence between equilibrium biphasic and triphasic material properties in mixture models of articular cartilage.

A paradigm for functional tissue engineering of articular cartilage via applied physiologic deformational loading.

Experimental verification of the role of interstitial fluid pressurization in cartilage lubrication.

Anisotropic strain-dependent material properties of bovine articular cartilage in the transitional range from tension to compression.

Role of cell-associated matrix in the development of free-swelling and dynamically loaded chondrocyte-seeded agarose gels.

Functional tissue engineering of chondral and osteochondral constructs.

Microscale frictional response of bovine articular cartilage from atomic force microscopy.

A layered agarose approach to fabricate depth-dependent inhomogeneity in chondrocyte-seeded constructs.

Anisotropy, inhomogeneity, and tension-compression nonlinearity of human glenohumeral cartilage in finite deformation.

Cartilage interstitial fluid load support in unconfined compression following enzymatic digestion.

Effects of enzymatic degradation on the frictional response of articular cartilage in stress relaxation.

Effect of dynamic loading on the frictional response of bovine articular cartilage.

Direct measurement of osmotic pressure of glycosaminoglycan solutions by membrane osmometry at room temperature.

Spatial and temporal development of chondrocyte-seeded agarose constructs in free-swelling and dynamically loaded cultures.

Patellofemoral joint biomechanics and tissue engineering.

A mixture theory analysis for passive transport in osmotic loading of cells.

Frictional response of bovine articular cartilage under creep loading following proteoglycan digestion with chondroitinase ABC.

A theoretical analysis of water transport through chondrocytes.

Dynamic response of immature bovine articular cartilage in tension and compression, and nonlinear viscoelastic modeling of the tensile response.

Spatially varying material properties of the rat caudal intervertebral disc.

Dynamic deformational loading results in selective application of mechanical stimulation in a layered, tissue-engineered cartilage construct.

Chondroitin sulfate reduces the friction coefficient of articular cartilage.

A tissue level tolerance criterion for living brain developed with an in vitro model of traumatic mechanical loading.

On the theory of reactive mixtures for modeling biological growth.

Anisotropy of fibrous tissues in relation to the distribution of tensed and buckled fibers.

The temporal response of the friction coefficient of articular cartilage depends on the contact area.

Equivalence between short-time biphasic and incompressible elastic material responses.

In-situ measurements of chondrocyte deformation under transient loading.

Osmotic loading of spherical gels: a biomimetic study of hindered transport in the cell protoplasm.

Culture duration modulates collagen hydrolysate-induced tissue remodeling in chondrocyte-seeded agarose hydrogels.

The effect of applied compressive loading on tissue-engineered cartilage constructs cultured with TGF-beta3.

Characterization of the mechanical properties and mineral distribution of the anterior cruciate ligament-to-bone insertion site.

Heterogeneous transmural proteoglycan distribution provides a mechanism for regulating residual stresses in the aorta.

Low-serum media and dynamic deformational loading in tissue engineering of articular cartilage.

Effects of sustained interstitial fluid pressurization under migrating contact area, and boundary lubrication by synovial fluid, on cartilage friction.

Characterization of the structure-function relationship at the ligament-to-bone interface.

Differences in interleukin-1 response between engineered and native cartilage.

The effect of devitalized trabecular bone on the formation of osteochondral tissue-engineered constructs.

Scaffold degradation elevates the collagen content and dynamic compressive modulus in engineered articular cartilage.

Analysis of radial variations in material properties and matrix composition of chondrocyte-seeded agarose hydrogel constructs.

Physiologic deformational loading does not counteract the catabolic effects of interleukin-1 in long-term culture of chondrocyte-seeded agarose constructs.

Dynamic loading of deformable porous media can induce active solute transport.

Two-dimensional strain fields on the cross-section of the bovine humeral head under contact loading.

Genipin enhances the mechanical properties of tissue-engineered cartilage and protects against inflammatory degradation when used as a medium supplement.

Influence of chondroitin sulfate on the biochemical, mechanical and frictional properties of cartilage explants in long-term culture.

Influence of temporary chondroitinase ABC-induced glycosaminoglycan suppression on maturation of tissue-engineered cartilage.

Zonal chondrocytes seeded in a layered agarose hydrogel create engineered cartilage with depth-dependent cellular and mechanical inhomogeneity.

A frame-invariant formulation of Fung elasticity.

Investigation of the frictional response of osteoarthritic human tibiofemoral joints and the potential beneficial tribological effect of healthy synovial fluid.

Two-dimensional strain fields on the cross-section of the human patellofemoral joint under physiological loading.

Integrative biomechanics: a paradigm for clinical applications of fundamental mechanics.

Modeling the matrix of articular cartilage using a continuous fiber angular distribution predicts many observed phenomena.

The role of interstitial fluid pressurization in articular cartilage lubrication.

Effect of dynamic loading on the transport of solutes into agarose hydrogels.

Continuum modeling of biological tissue growth by cell division, and alteration of intracellular osmolytes and extracellular fixed charge density.

Passaged adult chondrocytes can form engineered cartilage with functional mechanical properties: a canine model.

Influence of the partitioning of osmolytes by the cytoplasm on the passive response of cells to osmotic loading.

Effects of dexamethasone on the functional properties of cartilage explants during long-term culture.

Dependence of zonal chondrocyte water transport properties on osmotic environment.

Dynamic mechanical loading enhances functional properties of tissue-engineered cartilage using mature canine chondrocytes.

Electrostatic and non-electrostatic contributions of proteoglycans to the compressive equilibrium modulus of bovine articular cartilage.

Modeling of active transmembrane transport in a mixture theory framework.

Multigenerational interstitial growth of biological tissues.

Bioactive stratified polymer ceramic-hydrogel scaffold for integrative osteochondral repair.

Validation of theoretical framework explaining active solute uptake in dynamically loaded porous media.

Effect of sulfated glycosaminoglycan digestion on the transverse permeability of medial collateral ligament.

Duty Cycle of Deformational Loading Influences the Growth of Engineered Articular Cartilage.

Response of engineered cartilage to mechanical insult depends on construct maturity.

Finite element algorithm for frictionless contact of porous permeable media under finite deformation and sliding.

Anisotropic hydraulic permeability under finite deformation.

Characterization of the Concentration-Dependence of Solute Diffusivity and Partitioning in a Model Dextran-Agarose Transport System.

The role of mass balance equations in growth mechanics illustrated in surface and volume dissolutions.

Coculture of engineered cartilage with primary chondrocytes induces expedited growth.

Dynamic loading of immature epiphyseal cartilage pumps nutrients out of vascular canals.

Growth factor priming of synovium-derived stem cells for cartilage tissue engineering.

Effects of hypertonic (NaCl) two-dimensional and three-dimensional culture conditions on the properties of cartilage tissue engineered from an expanded mature bovine chondrocyte source.

Transient supplementation of anabolic growth factors rapidly stimulates matrix synthesis in engineered cartilage.

Finite element implementation of mechanochemical phenomena in neutral deformable porous media under finite deformation.

Solute transport across a contact interface in deformable porous media.

FEBio: Finite Elements for Biomechanics.

Trimethylamine N-oxide as a media supplement for cartilage tissue engineering.

Shearing of synovial fluid activates latent TGF-β.

Microbubbles as biocompatible porogens for hydrogel scaffolds.

Mechanics of Cell Growth.

Toward engineering a biological joint replacement.

Articular cartilage wear characterization with a particle sizing and counting analyzer.

Biomechanical roles of medial pooling of glycosaminoglycans in thoracic aortic dissection.

Dynamic mechanical compression of devitalized articular cartilage does not activate latent TGF-β.

Insulin, ascorbate, and glucose have a much greater influence than transferrin and selenous acid on the in vitro growth of engineered cartilage in chondrogenic media.

Interstitial growth and remodeling of biological tissues: tissue composition as state variables.

Accumulation of exogenous activated TGF-β in the superficial zone of articular cartilage.

Multiphasic finite element framework for modeling hydrated mixtures with multiple neutral and charged solutes.

Tissue-engineered articular cartilage exhibits tension-compression nonlinearity reminiscent of the native cartilage.

Applied osmotic loading for promoting development of engineered cartilage.

Synthesis rates and binding kinetics of matrix products in engineered cartilage constructs using chondrocyte-seeded agarose gels.

Finite element prediction of transchondral stress and strain in the human hip.

Effect of glutaraldehyde fixation on the frictional response of immature bovine articular cartilage explants.

Growth factor priming differentially modulates components of the extracellular matrix proteome in chondrocytes and synovium-derived stem cells.

Computational modeling of chemical reactions and interstitial growth and remodeling involving charged solutes and solid-bound molecules.

Large, stratified, and mechanically functional human cartilage grown in vitro by mesenchymal condensation.

Passage-dependent relationship between mesenchymal stem cell mobilization and chondrogenic potential.

Nutrient channels and stirring enhanced the composition and stiffness of large cartilage constructs.

Matrix Production in Large Engineered Cartilage Constructs Is Enhanced by Nutrient Channels and Excess Media Supply.

Human chondrocyte migration behaviour to guide the development of engineered cartilage.

Toward patient-specific articular contact mechanics.

Viscoelasticity using reactive constrained solid mixtures.

Fabrication of tissue engineered osteochondral grafts for restoring the articular surface of diarthrodial joints.

Wear and damage of articular cartilage with friction against orthopedic implant materials.

A Gauss-Kronrod-Trapezoidal integration scheme for modeling biological tissues with continuous fiber distributions.

Long-term storage and preservation of tissue engineered articular cartilage.

Porous titanium bases for osteochondral tissue engineering.

The friction coefficient of shoulder joints remains remarkably low over 24 h of loading.

Heterogeneous engineered cartilage growth results from gradients of media-supplemented active TGF-β and is ameliorated by the alternative supplementation of latent TGF-β.

Biphasic Analysis of Cartilage Stresses in the Patellofemoral Joint.

Cytokine preconditioning of engineered cartilage provides protection against interleukin-1 insult.

Grading of osteoarthritic cartilage: Correlations between histology and biomechanics.

High intensity focused ultrasound as a tool for tissue engineering: Application to cartilage.

Continuum theory of fibrous tissue damage mechanics using bond kinetics: application to cartilage tissue engineering.

A puzzle assembly strategy for fabrication of large engineered cartilage tissue constructs.

Dexamethasone Release from Within Engineered Cartilage as a Chondroprotective Strategy Against Interleukin-1α.

Transient expression of the diseased phenotype of osteoarthritic chondrocytes in engineered cartilage.

High seeding density of human chondrocytes in agarose produces tissue-engineered cartilage approaching native mechanical and biochemical properties.

Optimizing nutrient channel spacing and revisiting TGF-beta in large engineered cartilage constructs.

Nutrient Channels Aid the Growth of Articular Surface-Sized Engineered Cartilage Constructs.

Constrained Cage Culture Improves Engineered Cartilage Functional Properties by Enhancing Collagen Network Stability.

Toward understanding the role of cartilage particulates in synovial inflammation.

FEBio: History and Advances.

Fibroblast-like synoviocyte mechanosensitivity to fluid shear is modulated by interleukin-1α.

Finite Element Framework for Computational Fluid Dynamics in FEBio.

Perspectives on Sharing Models and Related Resources in Computational Biomechanics Research.

Hip chondrolabral mechanics during activities of daily living: Role of the labrum and interstitial fluid pressurization.

A Surface-to-Surface Finite Element Algorithm for Large Deformation Frictional Contact in febio.

Finite Element Formulation of Multiphasic Shell Elements for Cell Mechanics Analyses in FEBio.

A Functional Tissue-Engineered Synovium Model to Study Osteoarthritis Progression and Treatment.

A Plugin Framework for Extending the Simulation Capabilities of FEBio.

Physiologic Medium Maintains the Homeostasis of Immature Bovine Articular Cartilage Explants in Long-Term Culture.

A Formulation for Fluid Structure-Interactions in FEBio Using Mixture Theory.

Cartilage Wear Particles Induce an Inflammatory Response Similar to Cytokines in Human Fibroblast-Like Synoviocytes.

Simulating cerebral edema and delayed fatality after traumatic brain injury using triphasic swelling biomechanics.

Sustained low-dose dexamethasone delivery via a PLGA microsphere-embedded agarose implant for enhanced osteochondral repair.

Pulsed electromagnetic fields promote repair of focal articular cartilage defects with engineered osteochondral constructs.

Immature bovine cartilage wear by fatigue failure and delamination.

Modeling Pulse Wave Propagation Through a Stenotic Artery With Fluid Structure Interaction: A Validation Study Using Ultrasound Pulse Wave Imaging.

Tissue engineered autologous cartilage-bone grafts for temporomandibular joint regeneration.

Direct Osmotic Pressure Measurements in Articular Cartilage Demonstrate Nonideal and Concentration-Dependent Phenomena.

Sustained Delivery of SB-431542, a Type I Transforming Growth Factor Beta-1 Receptor Inhibitor, to Prevent Arthrofibrosis.

Finite Element Implementation of Biphasic-Fluid Structure Interactions in febio.

A Hybrid Reactive Multiphasic Mixture With a Compressible Fluid Solvent.

A Finite Element Algorithm for Large Deformation Biphasic Frictional Contact Between Porous-Permeable Hydrated Soft Tissues.

Attachment of cartilage wear particles to the synovium negatively impacts friction properties.

On the use of constrained reactive mixtures of solids to model finite deformation isothermal elastoplasticity and elastoplastic damage mechanics.

How Does Chondrolabral Damage and Labral Repair Influence the Mechanics of the Hip in the Setting of Cam Morphology? A Finite-Element Modeling Study.

Continuum Thermodynamics of Constrained Reactive Mixtures.

Toward Development of a Diabetic Synovium Culture Model.

A Hybrid Biphasic Mixture Formulation for Modeling Dynamics in Porous Deformable Biological Tissues.