Brahm H. Segal

Thioglycollate peritonitis in mice lacking C5, 5-lipoxygenase, or p47(phox): complement, leukotrienes, and reactive oxidants in acute inflammation.

Invasive pulmonary filamentous fungal infection in a patient receiving inhaled corticosteroid therapy.

Efficacy of high-efficiency particulate air filtration in preventing aspergillosis in immunocompromised patients with hematologic malignancies.

Phagocyte NADPH oxidase, but not inducible nitric oxide synthase, is essential for early control of Burkholderia cepacia and chromobacterium violaceum infection in mice.

Fungal infections in nontransplant patients with hematologic malignancies.

Deficiency of NADPH oxidase components p47phox and gp91phox caused granulomatous synovitis and increased connective tissue destruction in experimental arthritis models.

p47phox deficiency impairs NF-kappa B activation and host defense in Pseudomonas pneumonia.

Linezolid-resistant Enterococcus faecalis isolated from a cord blood transplant recipient.

Invasive filamentous fungal infections in allogeneic hematopoietic stem cell transplant recipients after recovery from neutropenia: clinical, radiologic, and pathologic characteristics.

Posaconazole as salvage therapy in patients with chronic granulomatous disease and invasive filamentous fungal infection.

Long-term use of oral beclomethasone dipropionate for the treatment of gastrointestinal graft-versus-host disease.

Current approaches to diagnosis and treatment of invasive aspergillosis.

Antibacterial prophylaxis in patients with cancer and neutropenia.

Immunotherapy for fungal infections.

Effect of amphotericin B and micafungin combination on survival, histopathology, and fungal burden in experimental aspergillosis in the p47phox-/- mouse model of chronic granulomatous disease.

Dapsone-induced methemoglobinemia after hematopoietic stem cell transplantation.

Heat shock proteins as vaccine adjuvants in infections and cancer.

Aspergillus fumigatus extract differentially regulates antigen-specific CD4+ and CD8+ T cell responses to promote host immunity.

Review of epidemiology, diagnosis, and treatment of invasive mould infections in allogeneic hematopoietic stem cell transplant recipients.

Altered granulopoietic profile and exaggerated acute neutrophilic inflammation in mice with targeted deficiency in the sialyltransferase ST6Gal I.

Clinical research in the lay press: irresponsible journalism raises a huge dose of doubt.

Issues related to the design and interpretation of clinical trials of salvage therapy for invasive mold infection.

Multicenter, noncomparative study of caspofungin in combination with other antifungals as salvage therapy in adults with invasive aspergillosis.

Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice.

Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: an externally controlled trial.

Prevention and early treatment of invasive fungal infection in patients with cancer and neutropenia and in stem cell transplant recipients in the era of newer broad-spectrum antifungal agents and diagnostic adjuncts.

Modeling the combination of amphotericin B, micafungin, and nikkomycin Z against Aspergillus fumigatus in vitro using a novel response surface paradigm.

Antibacterial prophylaxis in patients with neutropenia.

Ganciclovir inhibits lymphocyte proliferation by impairing DNA synthesis.

Combination antifungals: an update.

Immunotherapy for fungal infections with special emphasis on central nervous system infections.

Role of macrophages in host defense against aspergillosis and strategies for immune augmentation.

Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America.

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.

Prevention and treatment of cancer-related infections.

Broad-spectrum antifungal prophylaxis in patients with cancer at high risk for invasive mold infections: point.

Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group.

Defining responses to therapy and study outcomes in clinical trials of invasive fungal diseases: Mycoses Study Group and European Organization for Research and Treatment of Cancer consensus criteria.

Antifungal agents in hematopoietic stem cell transplantation.

Invasive aspergillosis in chronic granulomatous disease.

Aspergillosis.

Prevention and treatment of invasive fungal diseases in neutropenic patients.

Prevention, diagnosis, and treatment of invasive fungal infections in patients with cancer and neutropenia.

Infection control measures to prevent invasive mould diseases in hematopoietic stem cell transplant recipients.

Editorial: Special issue, "invasive fungal diseases in allogeneic hematopoietic stem cell transplant recipients".

Altered eosinophil profile in mice with ST6Gal-1 deficiency: an additional role for ST6Gal-1 generated by the P1 promoter in regulating allergic inflammation.

NADPH oxidase limits innate immune responses in the lungs in mice.

Pulmonary aspergillosis: clinical presentation, diagnostic tests, management and complications.

Role of NADPH oxidase in host defense against aspergillosis.

Proceedings from the 4th Advances Against Aspergillosis Conference, February 4-6, 2010, Rome, Italy.

Antifungal prophylaxis and therapy in patients with hematological malignancies and hematopoietic stem cell transplant recipients.

Chronic granulomatous disease: lessons from a rare disorder.

Nrf2 regulates chronic lung inflammation and B-cell responses to nontypeable Haemophilus influenzae.

Characterization of vancomycin pharmacokinetics in the adult acute myeloid leukemia population.

Transmission of resistant bacteria in intensive care.

Thematic issue: immunity, inflammation and fungal infections.

Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense.

Reactive oxygen species produced by the NADPH oxidase 2 complex in monocytes protect mice from bacterial infections.

Regulation of innate immunity by NADPH oxidase.

Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner.

Interferon regulatory factor-8 is important for histone deacetylase inhibitor-mediated antitumor activity.

Tracing conidial fate and measuring host cell antifungal activity using a reporter of microbial viability in the lung.

NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury.

NETosis and NADPH oxidase: at the intersection of host defense, inflammation, and injury.

Identification of myeloid cell subsets in murine lungs using flow cytometry.

Monocyte- and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice.

NADPH oxidase limits lipopolysaccharide-induced lung inflammation and injury in mice through reduction-oxidation regulation of NF-κB activity.

Myeloid-derived suppressor cells modulate immune responses independently of NADPH oxidase in the ovarian tumor microenvironment in mice.

NF-κB inhibition after cecal ligation and puncture reduces sepsis-associated lung injury without altering bacterial host defense.

NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.

Nrf2 amplifies oxidative stress via induction of Klf9.

Prevention of infection in cancer patients.

Dectin-1-Dependent LC3 Recruitment to Phagosomes Enhances Fungicidal Activity in Macrophages.