Ewan C. Goligher

Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome and Posterior Probability of Mortality Benefit in a Post Hoc Bayesian Analysis of a Randomized Clinical Trial.

Diaphragmatic myotrauma: a mediator of prolonged ventilation and poor patient outcomes in acute respiratory failure.

Diaphragm-protective mechanical ventilation.

Myotrauma in mechanically ventilated patients.

Withholding or withdrawing life support versus physician-assisted death: a distinction with a difference?

Lung- and Diaphragm-protective Ventilation in Acute Respiratory Distress Syndrome: Rationale and Challenges.

Optimal Ventilator Strategies in Acute Respiratory Distress Syndrome.

Determinants of the effect of extracorporeal carbon dioxide removal in the SUPERNOVA trial: implications for trial design.

Respiratory Drive in Critically Ill Patients. Pathophysiology and Clinical Implications.

A novel non-invasive method to detect excessively high respiratory effort and dynamic transpulmonary driving pressure during mechanical ventilation.

Editorial: Lung and diaphragm-protective ventilation: setting new concepts in historical context.

Association of Low Baseline Diaphragm Muscle Mass With Prolonged Mechanical Ventilation and Mortality Among Critically Ill Adults.

Airway Occlusion Pressure As an Estimate of Respiratory Drive and Inspiratory Effort during Assisted Ventilation.

Monitoring Patient Respiratory Effort During Mechanical Ventilation: Lung and Diaphragm-Protective Ventilation.

Lung- and Diaphragm-Protective Ventilation.

Monitoring patient-ventilator interaction by an end-expiratory occlusion maneuver.

Association of Mortality with Neuromuscular Blockade Differs according to Baseline Diaphragm Thickness.

Anti-Thrombotic Therapy to Ameliorate Complications of COVID-19 (ATTACC): Study design and methodology for an international, adaptive Bayesian randomized controlled trial.

Anticipating and managing coagulopathy and thrombotic manifestations of severe COVID-19.

Comparing the Effects of Tidal Volume, Driving Pressure, and Mechanical Power on Mortality in Trials of Lung-Protective Mechanical Ventilation.

Effect of Driving Pressure Change During Extracorporeal Membrane Oxygenation in Adults With Acute Respiratory Distress Syndrome: A Randomized Crossover Physiologic Study.

Validity of Empirical Estimates of the Ratio of Dead Space to Tidal Volume in ARDS.

Response to Ventilator Adjustments for Predicting Acute Respiratory Distress Syndrome Mortality. Driving Pressure versus Oxygenation.

Clinical strategies for implementing lung and diaphragm-protective ventilation: avoiding insufficient and excessive effort.

Clinical trials in critical care: can a Bayesian approach enhance clinical and scientific decision making?

Is severe COVID-19 pneumonia a typical or atypical form of ARDS? And does it matter?

Searching for the Optimal PEEP in Patients Without ARDS: High, Low, or in Between?

A manifesto for the future of ICU trials.

Duration of diaphragmatic inactivity after endotracheal intubation of critically ill patients.

Association of Thoracic Computed Tomographic Measurements and Outcomes in Patients with Hematologic Malignancies Requiring Mechanical Ventilation.

Effect of Lowering Vt on Mortality in Acute Respiratory Distress Syndrome Varies with Respiratory System Elastance.

Diaphragm echodensity in mechanically ventilated patients: a description of technique and outcomes.

Postextubation Respiratory Support: Of Clinical Trials and Clinical Decisions.

Abdominal Muscle Use During Spontaneous Breathing and Cough in Patients Who Are Mechanically Ventilated: A Bi-center Ultrasound Study.

How cutting-edge trial design can assess outcomes.

Association of different positive end-expiratory pressure selection strategies with all-cause mortality in adult patients with acute respiratory distress syndrome.

What Can We Learn From Monitoring Diaphragm Activity in Infants?

Noninvasive respiratory support following extubation in critically ill adults: a systematic review and network meta-analysis.

Impact of Reverse Triggering Dyssynchrony during Lung-Protective Ventilation on Diaphragm Function: An Experimental Model.

Association of Positive End-Expiratory Pressure and Lung Recruitment Selection Strategies with Mortality in Acute Respiratory Distress Syndrome: A Systematic Review and Network Meta-analysis.

Phrenic Nerve Block and Respiratory Effort in Pigs and Critically Ill Patients with Acute Lung Injury.

EXpert consensus On Diaphragm UltraSonography in the critically ill (EXODUS): a Delphi consensus statement on the measurement of diaphragm ultrasound-derived parameters in a critical care setting.

Physiology Is Vital to Precision Medicine in Acute Respiratory Distress Syndrome and Sepsis.

Validation of a Web-based Platform for Online Training in Point-of-Care Diaphragm Ultrasound.

Phrenic nerve stimulation to protect the diaphragm, lung, and brain during mechanical ventilation.

Noninvasive and invasive mechanical ventilation for neurologic disorders.

Strategies for lung- and diaphragm-protective ventilation in acute hypoxemic respiratory failure: a physiological trial.

A Window Into the Future: The Diagnostic and Prognostic Utility of Respiratory Muscle Ultrasound in Optimizing Mechanical Ventilation.

The religious character of secular arguments supporting euthanasia and what it implies for conscientious practice in medicine.

Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study.

Linking Acute Physiology to Outcomes in the ICU: Challenges and Solutions for Research.

Monitoring Respiratory Effort and Lung-distending Pressure Noninvasively during Mechanical Ventilation: Ready for Prime Time.

Diaphragm Neurostimulation Assisted Ventilation in Critically Ill Patients.

Association of Days Alive and at Home at Day 90 After Intensive Care Unit Admission With Long-term Survival and Functional Status Among Mechanically Ventilated Patients.

Heterogeneous Treatment Effects of Therapeutic-Dose Heparin in Patients Hospitalized for COVID-19.

Lung Recruitment Assessed by Electrical Impedance Tomography (RECRUIT): A Multicenter Study of COVID-19 Acute Respiratory Distress Syndrome.

Reply to Fernández.

Driving pressure: applying the concept at the bedside.

Bringing Clinical Trials to the Bedside: Conditional Average Treatment Effects in the Balanced Solution versus Saline in Intensive Care Study (BaSICS) Trial.

Heterogeneous Treatment Effects of Extracorporeal CO Removal in Acute Hypoxemic Respiratory Failure.

Driving pressure: pitfalls of methods that do not use esophageal pressure measurement. Author's reply.

Proof of Concept for Continuous On-Demand Phrenic Nerve Stimulation to Prevent Diaphragm Disuse during Mechanical Ventilation (STIMULUS): A Phase 1 Clinical Trial.

Phrenic Nerve Stimulation for Acute Respiratory Failure.

Simvastatin in Critically Ill Patients with Covid-19.

Lung and Diaphragm Protection During Mechanical Ventilation: Synchrony Matters.