Michael Shtutman

Tumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ζ 2 renders tumor cells dependent on its paralogous gene COPZ1.

A subunit of coatomer protein complex offers a novel tumor-specific target through a surprising mechanism.

Transcriptomes and shRNA suppressors in a TP53 allele-specific model of early-onset colon cancer in African Americans.

Purification of high-quality RNA from synthetic polyethylene glycol-based hydrogels.

Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells.

Prefrontal microRNA-221 Mediates Environmental Enrichment-Induced Increase of Locomotor Sensitivity to Nicotine.

Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast Cancer.

Arginyltransferase suppresses cell tumorigenic potential and inversely correlates with metastases in human cancers.

PDE11A regulates social behaviors and is a key mechanism by which social experience sculpts the brain.

Transgenerational attenuation of opioid self-administration as a consequence of adolescent morphine exposure.

Cellular Model of p21-Induced Senescence.

Crystal structure of truncated human coatomer protein complex subunit ζ1 (Copζ1).

Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer.

Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screen.

Impact of Pharmacogenetics on Efficacy and Safety of Statin Therapy for Dyslipidemia.

CDK8/19 Mediator kinases potentiate induction of transcription by NFκB.

MOLIERE: Automatic Biomedical Hypothesis Generation System.

hnRNPs Interacting with mRNA Localization Motifs Define Axonal RNA Regulons.

Coordination Analysis of Gene Expression Points to the Relative Impact of Different Regulators During Endoplasmic Reticulum Stress.

Identifying Cancers Impacted by CDK8/19.

Inhibition of the Dead Box RNA Helicase 3 Prevents HIV-1 Tat and Cocaine-Induced Neurotoxicity by Targeting Microglia Activation.

tRNA-Derived Fragments Can Serve as Arginine Donors for Protein Arginylation.

A strategy for the identification of paracrine regulators of cancer cell migration.

Pharmacological inhibition of DEAD-Box RNA Helicase 3 attenuates stress granule assembly.

Genomic variation in captive deer mouse (Peromyscus maniculatus) populations.

Large-Scale Validation of Hypothesis Generation Systems via Candidate Ranking.

Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo.

CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins.

Therapeutically targeting the consequences of HIV-1-associated gastrointestinal dysbiosis: Implications for neurocognitive and affective alterations.

Suppression of HIV and cocaine-induced neurotoxicity and inflammation by cell penetrable itaconate esters.

Exposure to angiotensin-converting enzyme inhibitors that cross the blood-brain barrier and the risk of dementia among patients with human immunodeficiency virus.

Quantification of the immunometabolite protein modifications S-2-succinocysteine and 2,3-dicarboxypropylcysteine.

Glycosaminoglycan modifications of betaglycan regulate ectodomain shedding to fine-tune TGF-β signaling responses in ovarian cancer.

Suppression of HIV-TAT and cocaine-induced neurotoxicity and inflammation by cell penetrable itaconate esters.

Correlation Analysis of Genetic Mutations and Galectin Levels in Breast Cancer Patients.

Heart failure with preserved ejection fraction in pigs causes shifts in posttranscriptional checkpoints.

Exposure to angiotensin-converting enzyme inhibitors that cross the blood-brain barrier and the risk of dementia among People Living with HIV.

Schizophrenia, Off-Label Antipsychotics, and Dementia Risk in People with HIV.

The impact of diet induced obesity on 5 fluorouracil-induced tumor and liver immune cell cytotoxicity.

Single Particle Tracking of Genetically Encoded Nanoparticles: Optimizing Expression for Cytoplasmic Diffusion Studies.