Isaac S. Carrico

Biosynthesis of proteins incorporating a versatile set of phenylalanine analogues.

A designed phenylalanyl-tRNA synthetase variant allows efficient in vivo incorporation of aryl ketone functionality into proteins.

Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics.

Lithographic patterning of photoreactive cell-adhesive proteins.

Introducing genetically encoded aldehydes into proteins.

Chemoselective modification of proteins: hitting the target.

Nanoparticles: designer labels for virus coats.

New frontiers in protein bioconjugation.

Metabolic cross-talk allows labeling of O-linked beta-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway.

Targeted and armed oncolytic adenovirus via chemoselective modification.

Chemoselective modification of viral proteins bearing metabolically introduced "clickable" amino acids and sugars.

Altering Adenoviral Tropism via Click Modification with ErbB Specific Ligands.