Edwin C. Oh

Photoreceptor-specific nuclear receptor NR2E3 functions as a transcriptional activator in rod photoreceptors.

Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors.

Transformation of cone precursors to functional rod photoreceptors by bZIP transcription factor NRL.

Afferent control of horizontal cell morphology revealed by genetic respecification of rods and cones.

Rod differentiation factor NRL activates the expression of nuclear receptor NR2E3 to suppress the development of cone photoreceptors.

Retinoid-related orphan nuclear receptor RORbeta is an early-acting factor in rod photoreceptor development.

Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).

Functional analyses of variants reveal a significant role for dominant negative and common alleles in oligogenic Bardet-Biedl syndrome.

Planar cell polarity acts through septins to control collective cell movement and ciliogenesis.

Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry.

DISC1-dependent switch from progenitor proliferation to migration in the developing cortex.

Neuroscience: Imprinting in the brain.

Cilia in vertebrate development and disease.

Mutations in LOXHD1, a recessive-deafness locus, cause dominant late-onset Fuchs corneal dystrophy.

KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant.

Context-dependent regulation of Wnt signaling through the primary cilium.

Recurrent de novo mutations in PACS1 cause defective cranial-neural-crest migration and define a recognizable intellectual-disability syndrome.