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National Defense Medical College Research Institute

2 ARTICLES PUBLISHED IN JoVE

Neuroscience

Simultaneous Evaluation of Cerebral Hemodynamics and Light Scattering Properties of the In Vivo Rat Brain Using Multispectral Diffuse Reflectance Imaging

Izumi Nishidate¹, Afrina Mustari¹, Satoko Kawauchi², Shunichi Sato², Manabu Sato³

¹Graduate School of Bio-application & Systems Engineering, Tokyo University of Agriculture & Technology, ²Division of Biomedical Information Sciences, National Defense Medical College Research Institute, ³Graduate School of Science and Engineering, Yamagata University

The simultaneous evaluation of cerebral hemodynamics and the light scattering properties of in vivo rat brain tissue is demonstrated using a conventional multispectral diffuse reflectance imaging system.

Bioengineering

Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy

Afrina Mustari^*1, Izumi Nishidate^*1, Md. Abdul Wares^1,6, Takaaki Maeda², Satoko Kawauchi³, Shunichi Sato³, Manabu Sato⁴, Yoshihisa Aizu⁵

¹Graduate School of Bio-application & Systems Engineering, Tokyo University of Agriculture & Technology, ²Department of Mechanical Engineering, Kushiro National College of Technology, ³Division of Bioinformation and Therapeutic Systems, National Defense Medical College Research Institute, ⁴Graduate School of Science and Engineering, Yamagata University, ⁵College of Design and Manufacturing Technology, Muroran Institute of Technology, ⁶Department of Livestock Services, Ministry of Fisheries and Livestock, Government of Bangladesh

Here, we demonstrate how agarose-based tissue-mimicking optical phantoms are made and how their optical properties are determined using a conventional optical system with an integrating sphere.