Hunan Fangsheng Pharmaceutical Co., Ltd.
3 ARTICLES PUBLISHED IN JoVE
Biochemistry
Enhancing the Engraftment of Human Induced Pluripotent Stem Cell-derived Cardiomyocytes via a Transient Inhibition of Rho Kinase Activity
Meng Zhao 1, Yawen Tang 1, Patrick J. Ernst 1,2, Asher Kahn-Krell 1, Chengming Fan 1,3, Danielle Pretorius 1, Hanxi Zhu 1, Xi Lou 1, Lufang Zhou 2, Jianyi Zhang 1, Wuqiang Zhu 1
1Department of Biomedical Engineering, School of Medicine, School of Engineering, University of Alabama at Birmingham, 2Division of Cardiovascular Diseases, School of Medicine, School of Engineering, University of Alabama at Birmingham, 3Department of Cardiac Surgery, The Second Xiangya Hospital of Central South University
In this protocol, we demonstrate and elaborate on how to use human induced pluripotent stem cells for cardiomyocyte differentiation and purification, and further, on how to improve its transplantation efficiency with Rho-associated protein kinase inhibitor pretreatment in a mouse myocardial infarction model.
Medicine
Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Cheng Luo *1, Chengming Fan *1, Hao Zhang 1, Long Song 1, Yuhong Liu 1, Liming Liu 1
1Department of Cardiovascular Surgery, the Second Xiangya Hospital, Central South University
We summarize the Cox-Maze IV procedure concomitant with valvular surgery performed in patients with situs inversus dextrocardia at this institution.
Medicine
Ultrasound-Guided Induced Pluripotent Stem Cell-Derived Cardiomyocyte Implantation in Myocardial Infarcted Mice
Xun Wu 1, Kele Qin 1, Di Wang 2, Kun Xiang 1, Jun Peng 2, Jianjun Guo 3, Jinfu Yang 1,2, Chengming Fan 1,2,3
1Department of Cardiovascular Surgery, Second Xiangya Hospital, Central South University, 2Hunan Provincial Key Laboratory of Cardiovascular Research, 3Hunan Fangsheng Pharmaceutical Co., Ltd.
Ultrasound-guided cell delivery around the site of myocardial infarction in mice is a safe, effective, and convenient way of cell transplantation.
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