Aalen University
2 ARTICLES PUBLISHED IN JoVE
Bioengineering
Nanotopology of Cell Adhesion upon Variable-Angle Total Internal Reflection Fluorescence Microscopy (VA-TIRFM)
Michael Wagner 1, Petra Weber 1, Harald Baumann 1, Herbert Schneckenburger 1
1Hochschule Aalen, Institut für Angewandte Forschung
Topology of cell adhesion on a substrate is measured with nanometre precision by variable-angle total internal reflection fluorescence microscopy (VA-TIRFM).
Engineering
Single Plane Illumination Module and Micro-capillary Approach for a Wide-field Microscope
Thomas Bruns 1, Sarah Schickinger 1, Herbert Schneckenburger 1
1Institute of Applied Research, Aalen University
A module for single plane illumination microscopy (SPIM) is described which is easily adapted to an inverted wide-field microscope and optimized for 3-dimensional cell cultures. The sample is located within a rectangular capillary, and via a microfluidic system fluorescent dyes, pharmaceutical agents or drugs can be applied in small quantities.
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