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University of Perugia, Perugia, Italy

1 ARTICLES PUBLISHED IN JoVE

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A Comparative Analysis of Recombinant Protein Expression in Different Biofactories: Bacteria, Insect Cells and Plant Systems
Elisa Gecchele *1, Matilde Merlin *1, Annalisa Brozzetti 2, Alberto Falorni 2, Mario Pezzotti 1, Linda Avesani 1
1Department of Biotechnology, University of Verona, Verona, Italy, 2Department of Internal Medicine, University of Perugia, Perugia, Italy

In this study the expression of a target human recombinant protein in different production platforms was compared. We focused on traditional fermenter-based cultures and on plants, describing the set-up of each system and highlighting, on the basis of the reported results, the inherent limits and advantages for each platform.

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