Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens ApplicationNatascha Riehle *1,2, Sibylle Thude *3, Andreas Kandelbauer 1,2, Günter E. M. Tovar 3,4, Günter Lorenz 1,2
1Reutlingen Research Institute, Reutlingen University, 2School of Applied Chemistry, Reutlingen University, 3Fraunhofer-Institute for Interfacial Engineering and Biotechnology IGB, 4Institute of Interfacial Process Engineering and Plasma Technology IGVP, University of Stuttgart
This study describes synthetic routes for aminopropyl-terminated polydimethylsiloxanes and polydimethyl-methyl-phenyl-siloxane-block copolymers and for soft polysiloxane-based urea (PSU) elastomers. It presents the application of PSUs as accommodating an intraocular lens. An evaluation method for in vitro cytotoxicity is also described.
