Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker AnalysisPaola Marco-Casanova 1, Natalia Lukashchuk 1, Benedetta Lombardi 1, Veerendra Munugalavadla 2, Melanie M. Frigault 3, Elizabeth A. Harrington 1, J. Carl Barrett 3, Andrew J. Pierce 1
1Translational Medicine, R&D Oncology, AstraZeneca, 2Acerta Pharma, AstraZeneca Group, 3Translational Medicine, R&D Oncology, AstraZeneca
This protocol details clinically implementable preparation of high quality PBMC and plasma biosamples at the clinical trial site that can be used for translational biomarker analysis.
