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Core Research Laboratory, ISPRO

1 ARTICLES PUBLISHED IN JoVE

Cancer Research

Analysis of Lymph Node Volume by Ultra-High-Frequency Ultrasound Imaging in the Braf/Pten Genetically Engineered Mouse Model of Melanoma

Marianna Vitiello^1,2, Claudia Kusmic¹, Francesco Faita¹, Laura Poliseno^1,2

¹Institute of Clinical Physiology, National Research Council (IFC-CNR), ²Oncogenomics Unit, Core Research Laboratory, ISPRO

Melanoma is a very aggressive disease that quickly spreads to other organs. This protocol describes the application of ultra-high-frequency ultrasound imaging, coupled with 3D rendering, to monitor the volume of the inguinal lymph nodes in the Braf/Pten mouse model of metastatic melanoma.