Establishing 3-Dimensional Spheroids from Patient-Derived Tumor Samples and Evaluating their Sensitivity to DrugsNeta Moskovits 1,2, Ella Itzhaki 1,2, Nataly Tarasenko 1,2, Eva Chausky 1,2, Avital Bareket-Samish 3, Aleksandr Kaufman 1,2, Raisa Meerson 1,2, Salomon M. Stemmer 1,2,4
1Felsenstein Medical Research Center, 2Davidoff Center, Rabin Medical Center, 3BioInsight Ltd., 4Sackler Faculty of Medicine, Tel Aviv University
The present protocol describes generating 3D tumor culture models from primary cancer cells and evaluating their sensitivity to drugs using cell-viability assays and microscopic examinations.
