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Overview

1:01

Levels of Anesthesia

2:16

Anesthesia Induction Procedures: Inhalation and Injection

7:15

Anesthetic Depth Assessment

10:27

Applications

12:06

Summary

麻醉诱导与维护

来源: 凯斯图尔特, RVT, RLATG, CMAR;瓦莱丽. 施罗德, RVT, RLATG。圣母大学, 在

实验室动物的护理和使用指南 (和 #34; 指南和 #34;) 指出疼痛评估和减轻是实验动物兽医护理的组成部分. 1 麻醉的定义是感觉或感受的损失。这是一个动态的事件, 涉及麻醉深度的变化与动物和 #39 的新陈代谢, 外科刺激, 或在外部环境的变化.

正确选择手术麻醉药和其他可能的疼痛程序必须由兽医确定。这是基于许多方面, 包括程序的范围和持续时间, 物种和应变, 年龄, 和生理状况的动物.

麻醉剂可作为剂或注射。手术麻醉可以使用注射和吸入麻醉剂的组合来完成。 2

1。吸入麻醉诱导

吸入麻醉包括异氟醚、七氟醚和地氟醚, 其中最常用的是异氟醚。这些麻醉药...

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正确使用麻醉药进行手术或其他潜在的痛苦的程序, 不仅对动物和 #39 的福祉至关重要, 而且对在过程中收集的科学数据的完整性也很重要。选择合适的麻醉团有很多变数。麻醉深度必须密切监测, 因为每个个体动物对药物的反应都不同。使用适当的麻醉和仔细的监测, 痛苦的程序可以完成, 没有疼痛和最小的生理变化的动物.

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  1. Institute for the Laboratory Animal Research. 2011. Guide for the care and use of laboratory animals, 8th ed. Washington (DC): National Academies Press.
  2. Tsukamoto, A., Serizawa, K., Sato, R., Yamazaki, J., and Inomata, T. 2015. Vital signs during injectable and inhalant anesthesia in mice. Experimental Animals. 64(1). 57-64.
  3. Kent Scientific Corporation. Retrieved from https://www.kentscientific.com/products/productView.asp?productID=6468&Mouse_Rat=CODA+High+Throughput&products=MouseSTAT%AE+Pulse+Oximeter+%26+Heart+Rate+Monitor+Module (accessed 10/15/15)
  4. Szczepan B et al. Intraoperative Physiological Monitoring in Rodent Surgical Research. Retrievd from https://www.alnmag.com/article/2012/10/intraoperative-physiological-monitoring-rodent-surgical-research  (accessed 10/15/15)
  5. Preanesthesia, Anesthesia, Analgesia, and Euthanasia. Laboratory Animal Medicine, 2nd ed. Ed Fox, J. G., Anderson, L. C., Loew, F. M., and Quimby, F. W. 2002. Academic Press. San Diego, CA.
  6. Ho, David et al. 2011. Heart Rate and Electrocardiography Monitoring in Mice. Current protocols in mouse biology. 1: 123-139. PMC. Web. 15 Sept. 2016.
  7. Smith, W. 1993. Responses of laboratory animals to some injectable anaethetics. Laboratory Animals. 27. 30-39.

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