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Overview

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Preoperative Preparations: Area and Animal Health

2:40

Prepping Steps: Shaving, Scrubbing, Positioning, and Draping

6:52

Intra and Postoperative Procedures

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Applications

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Summary

啮齿动物手术的考虑事项

来源: 凯斯图尔特, RVT, RLATG, CMAR;瓦莱丽. 施罗德, RVT, RLATG。圣母大学, 在

指南为实验室动物的关心和使用 1 规定, 啮齿动物的生存手术进行菌。无菌技术采用的具体做法, 最大限度地减少污染的外科手术部位, 包括病人的准备, 外科医生的准备, 消毒仪器和其他用品, 以及使用清洁和控制环境。前计划, 术中监护和术后护理是成功恢复动物生存手术的关键.

1. 和 #160;P resurgical 规划

虽然准则不要求在专用的外科手术设备中进行啮齿动物手术, 但使用的区域必须用适当的硬表面进行消毒消毒剂, 应按照制造商和 #39 的浓度和接触时间使用。该地区也应保持无杂波, 而不是在直接线的供应和排气管道, 因为草案可能导致低温的动物。在进行手术时, 应限制进入房间。外科准备 (特别是切除动物和 #39 的毛发), 以及术后恢复和护理的区域, ...

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通过使用无菌技术, 后感染的发生率大大缩短。在手术过程中尽量减少组织损伤, 采取预防措施预防体温过低, 控制术后疼痛和不适, 以及使用营养补充剂, 直到动物能够正常走动, 都会降低阴性的程度。代谢反应的手术过程和增加的概率成功的生存手术.

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  1. Institute for the Laboratory Animal Research. 2011. Guide for the care and use of laboratory animals, 8th ed. Washington (DC): National Academies Press.
  2. Bernal, J., Baldwin, M., Gleason, T., Kuhlman, S., Moore. G., and Talcott, M. 2009. Guidelines for Rodent Survival Surgery. Journal of Investigative Surgery. 22. 445-451
  3. Brauer, A., Perl, T., Uyanik , Z., English, M.J.M. ,Weyland, W., and Braun, U. 2004. Perioperative thermal insulation: minimal clinically important differences? British Journal of Anaesthesia 92:6. 836-840
  4. Guidelines for Survival Rodent Surgery. http://oacu.od.nih.gov/ARAC/documents/Rodent_Surgery.pdf  Accessed 11/11/15
  5. Eakin, K., Rowe, R.K., and Lifshitz, J. 2015. Modeling Fluid Percussion Injury
    Relevance to Human Traumatic Brain Injury in Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects. Taylor & Francis Group, LLC.
  6. Rodent Anesthesia and Analgesia. The University of British Columbia. Retrieved from https://animalcare.ubc.ca/conducting-your-research/rodent-anesthesia-and-analgesia

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