Name: making mr imaging child's play - pediatric neuroimaging protocol, guidelines and procedure
Uploaded: 2009-07-30T16:45:00
Description: Watch this Scientific Journal Video about Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure at JoVE.com

Ringraziamo partecipano bambini e le famiglie, tutto il personale presso l&#39;Ospedale dei Bambini di Boston (CHB) con particolare apprezzamento ai tecnici risonanza magnetica, senza il quale i nostri studi non è stato possibile condurre. Siamo particolarmente grati ad Arnold Cyr di partecipazione e di aiuto durante le nostre riprese video e al funzionamento direttore Patricia Devine a Waltham CHB. Grazie alla ricerca e allo staff tecnico al MIT di Athinoula A. Martinos Imaging Center per la condivisione di esperienza nella acquisizione delle immagini RM e analisi. Questa ricerca è stata finanziata dalla Fondazione H. Charles Hood, un ospedale pediatrico di Boston pilota sovvenzione e il Fondo nazionale svizzero (NMR)

Abbiamo incorporato generale le linee guida di test sperimentali così come la risonanza magnetica approcci specifici 12-23 in un protocollo di neuroimaging complete che guida i ricercatori e clinici durante le sessioni di neuroimaging con i bambini svegli di appena quattro anni di età. In primo luogo, ci proponiamo di sottolineare le linee guida generali test adattato per gli esami di risonanza magnetica. In secondo luogo, fornire un hands-on, passo-passo la descrizione del nostro protocollo di neuroimaging...

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L&#39;emergere di risonanza magnetica funzionale e strutturale per studiare il cervello umano ha facilitato le possibilità di esaminare tipici così come la struttura cerebrale atipica e funzioni e detiene quindi una grande promessa sia per scopi di ricerca e clinica 6. Tuttavia, studi di risonanza magnetica nelle fasce d&#39;età più giovani rimangono meno numerosi rispetto a quelli degli adulti, adolescenti o bambini, che è principalmente a causa di difficoltà tecniche e pratic...

making mr imaging child's play - pediatric neuroimaging protocol, guidelines and procedure

Nell&#39;ultimo decennio c&#39;è stato un aumento dell&#39;uso di strutturale e la risonanza magnetica funzionale (fMRI) per studiare le basi neuronali della percezione umana, la cognizione e del comportamento<sup&gt; 1, 2</sup&gt;. Inoltre, questo metodo non invasivo di imaging si è trasformata in uno strumento per i medici e ricercatori per esplorare lo sviluppo del cervello tipico e atipico. Anche se i progressi in strumenti di neuroimaging e le tecniche sono evidenti, (f), risonanza magnetica in giovani pazienti pediatrici è relativamente infrequente<sup&gt; 2</sup&gt;. Sfide pratiche e tecniche di imaging, quando i bambini presenti i clinici e gruppi di ricerca con un unico insieme di problemi<sup&gt; 3, 2</sup&gt;. Per citarne solo alcuni, i partecipanti si sono sfidati bambino da un bisogno di motivazione, la vigilanza e la cooperazione. L&#39;ansia può essere un ulteriore fattore da affrontare. Ricercatori o medici devono considerare vincoli di tempo, limitazione di movimento, il rumore di fondo dello scanner e scarsa familiarità con l&#39;ambiente scanner MR<sup&gt; 2,4-10</sup&gt;. Un uso progressivo di neuroimaging funzionale e strutturale nelle fasce di età più giovani, però, potrebbe ulteriormente aggiungere alla nostra comprensione dello sviluppo cerebrale. Per fare un esempio, molti gruppi di ricerca stanno attualmente lavorando per l&#39;individuazione precoce di disturbi dello sviluppo, potenzialmente ancor prima che i bambini presentano caratteristiche comportamentali associati<sup&gt; Eg11</sup&gt;. Varie strategie e tecniche sono stati segnalati come un mezzo per garantire il comfort e la cooperazione dei bambini durante le sessioni di neuroimaging. Gioca terapia<sup&gt; 12</sup&gt;, Approcci comportamentali<sup&gt; 13, 14,15, 16-18</sup&gt; E simulazione<sup&gt; 19</sup&gt;, L&#39;utilizzo delle aree scanner finto<sup&gt; 20,21</sup&gt;, Il rilassamento di base<sup&gt; 22</sup&gt; E una combinazione di queste tecniche<sup&gt; 23</sup&gt; Hanno tutti dimostrato di migliorare il rispetto dei partecipanti e quindi la risonanza magnetica qualità dei dati. Ancora più importante, queste strategie hanno dimostrato di aumentare il comfort delle famiglie e dei bambini coinvolti<sup&gt; 12</sup&gt;. Uno dei principali progressi di tali tecniche per la pratica clinica è la possibilità di evitare la sedazione o anestesia generale (GA) come un modo per gestire la conformità dei bambini durante le sessioni di imaging RM<sup&gt; 19,20</sup&gt;. Nel report video corrente, vi presentiamo un protocollo pediatrico neuroimaging con linee guida e procedure che hanno dimostrato di avere successo fino ad oggi nei bambini piccoli.

Watch this Scientific Journal Video about Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure at JoVE.com

Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure

Nonostante l&#39;aumento nell&#39;uso dei strutturali e la risonanza magnetica funzionale (fMRI) negli esseri umani, lo studio delle giovani popolazioni pediatriche rimane una sfida. Vi presentiamo un hands-on, passo-passo protocollo video, tra cui linee guida per medici e ricercatori che intendono svolgere (f), risonanza magnetica nei bambini piccoli.

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