Name: ole isacson: development of new therapies for parkinson's disease
Uploaded: 2007-04-29T00:00:00
Description: Watch this Scientific Journal Video about Ole Isacson: Development of New Therapies for Parkinson's Disease at JoVE.com

<ol>
	<li>Chung, C. Y., Seo, H., Sonntag, K. C., Brooks, A., Lin, L., Iasacson, O. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Cell+type+specific+gene+expression+of+midbrain+dopaminergic+neurons+reveals+molecules+involved+in+their+vulnerability.">Cell type specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability.</a> Hum. Mol. Genet. 14, 1709-1725 (2005).</li><li>Mendez, I., Sanchez-Pernaute, R., Cooper, O., Vinuela, A., Ferrari, D., Bjoerklund, L., Dagher, A., Isacson, O. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Cell+type+analysis+of+fetal+dopamine+cell+suspension+transplants+in+the+striatum+and+substantia+nigra+of+patients+with+Parkinson's+disease.">Cell type analysis of fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease.</a> Brain. 128 (7), 1498-1510 (2005).</li><li>Cooper, O., Isacson, O. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Intrastiatal+Transforming+Growth+Factor+Delivery+to+a+Model+of+Parkinson's+Disease+Induces+Proliferation+and+Migration+of+Endogenous+Adult+Neural+Progenitor+Cells+without+Differentiation+into+Dopaminergic+Neurons.">Intrastiatal Transforming Growth Factor Delivery to a Model of Parkinson's Disease Induces Proliferation and Migration of Endogenous Adult Neural Progenitor Cells without Differentiation into Dopaminergic Neurons.</a> J. Neurosci. 24 (41), 8924-8931 (2004).</li><li>Sanchez-Pernaute, R., Ferree, A., Cooper, O., Yu, M., Brownell, A. L., Isacson, O. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Selective+COX-2+inhibition+prevents+progressive+dopamine+neuron+degeneration+in+a+rat+mod+of+Parkinson's+disease.">Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat mod of Parkinson's disease.</a> Journal of Neuroinflammation. , (2004).</li><li>Isacson, O. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+production+and+use+of+cells+as+therapeutic+agents+in+neurodegenerative+diseases.">The production and use of cells as therapeutic agents in neurodegenerative diseases.</a> Lancet Neurology. 2 (7), 417-424 (2003).</li></ol>

ole isacson: development of new therapies for parkinson's disease

Watch this Scientific Journal Video about Ole Isacson: Development of New Therapies for Parkinson's Disease at JoVE.com

Ole Isacson: Development of New Therapies for Parkinson's Disease

OLE Isacson给出了一个简洁的概述，对帕金森病的原因，治疗策略，以及帕金森病研究的进展。

OLE Isacson：帕金森氏病的新疗法的发展

Research

JoVE Journal

Biology

Gibberella zeae Ascospore Production and Collection for Microarray Experiments.

Gibberella zeae子囊孢子生产和收集微阵列实验。

Fusarium graminearum Schwabe (teleomorph Gibberella zeae) is a plant pathogen causing scab disease on wheat and barley that reduces crop yield and grain ...

科研

生物学

ES Cell-derived Neuroepithelial Cell Cultures

ES细胞源性神经上皮细胞培养

ES cells have the potential to differentiate into cells from all germ layers, which makes them an attractive tool for the development of new therapies. In ...

Cortical Neurogenesis: Transitioning from Advances in the Laboratory to Cell-Based Therapies

皮层神经再生：从实验室中的研究进展过渡到细胞疗法

ALS - Motor Neuron Disease: Mechanism and Development of New Therapies

ALS - 运动神经元疾病：机制和新疗法的发展

Development of New Therapeutic Applications Using Microfluidics

使用微流体开发新的治疗应用

Application of a C. elegans Dopamine Neuron Degeneration Assay for the Validation of Potential Parkinson's Disease Genes

一个线虫多巴胺神经元退化含量的应用验证潜在的帕金森氏症基因

Improvements to the diagnosis and treatment of Parkinson's disease (PD) are dependent upon knowledge about susceptibility factors that render populations ...

Method for Culture of Early Chick Embryos ex vivo (New Culture)

Method for Culture of Early Chick Embryos ex vivo New Culture

文化早期鸡胚体外（新文化）的方法

The chick embryo is a valuable tool in the study of early embryonic development. Its transparency, accessibility and ease of manipulation, make it an ...

Murine Model for Parkinson's Disease: from 6-OH Dopamine Lesion to Behavioral Test

帕金森氏病的小鼠模型：从6 - OH多巴胺病变行为测试

Parkinson's disease (PD) affects at least 6.5 million people worldwide, irrespective of gender, social, ethnic, economic, or geographic boundaries. Key ...

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of  Obliterative Airway Disease

异位和原位气管移植小鼠模型研究闭塞性气道疾病的发展

Obliterative airway disease (OAD) is the major complication after lung transplantations that limits long term survival (1-7).
To study the ...

Principles of Rodent Surgery for the New Surgeon

鼠类外科的原则，为新的外科医生

For both scientific and animal welfare reasons, training in basic surgical concepts and techniques should be undertaken before ever seeking to perform ...