Name: vascular occlusion training for inclusion body myositis: a novel therapeutic approach
Uploaded: 2010-06-05T17:00:00
Description: Watch this Scientific Journal Video about Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach at JoVE.com

<p class="jove_content">我们想感谢胡里奥马亚先生在这个视频和先生乔尔S.托雷斯参加审查的手稿。布鲁诺Gualano Conselho全国Pesquisa发送Tecnologia支持。 </p>

<p class="jove_title"> 1。完整的血管闭塞压力的测定</p><ol><li>为了确定毫米汞柱，血压，血管闭塞，血管多普勒</li><li>在仰卧位病人躺在一个定制的血压袖带（180长x 80mm宽）是固定他的大腿上。 </li><li>检测胫后动脉位置后，多普勒探头，然后放置在确定病人的腿当场。 </li><li>声音信号产生多普勒机，因为它抓住了动脉搏动。 </li><li>然后定制血压袖带充气，直到它的胫后动脉ascultatory脉冲中断。 </li><li>完整的血管闭塞?...

<ol>
	<li>Needha, M., Mastaglia, F. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Inclusion+body+myositis:+current+pathogenetic+concepts+and+diagnostic+and+therapeutic+approaches.">Inclusion body myositis: current pathogenetic concepts and diagnostic and therapeutic approaches.</a> <em style='font-style: italic'>Lancet Neurol</em>. <b>6</b>, 620-631 (2007).</li><li>de Salles Painelli, V., Gualano, B., Artioli, G. G., de Sa Pinto, A. L., Bonfa, E., Lancha Junior, A. H., Lima, F. R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+possible+role+of+physical+exercise+on+the+treatment+of+idiopathic+inflammatory+myopathies.">The possible role of physical exercise on the treatment of idiopathic inflammatory myopathies.</a> <em style='font-style: italic'>Autoimmun. Rev</em>. <b>8</b>, 355-359 (2009).</li><li>Spector, S. A., Lemmer, J. T., Koffman, B. M., Fleisher, T. A., Feuerstein, I. M., Hurley, B. F., Dalakas, M. C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Safety+and+efficacy+of+strength+training+in+patients+with+sporadic+inclusion+body+myositis.">Safety and efficacy of strength training in patients with sporadic inclusion body myositis.</a> <em style='font-style: italic'>Muscle Nerve</em>. <b>20</b>, 1242-1248 (1997).</li><li>Gualano, B., Neves, M., Lima, F. R., de S&#225; Pinto, A. L., Laurentino, G., Borges, C., Baptista, L., Artioli, G. G., Aoki, M. S., Moriscot, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Training+with+Vascular+Occlusion+in+Inclusion+BodyMyositis:+A+Case+Study.">Training with Vascular Occlusion in Inclusion BodyMyositis: A Case Study.</a> <em style='font-style: italic'>Med. Sci. Sports Exerc</em>. , .</li><li>Takarada, Y., Takazawa, H., Sato, Y., Takebayashi, S., Tanaka, Y., Ishii, N. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Effects+of+resistance+exercise+combined+with+moderate+vascular+occlusion+on+muscular+function+in+humans.">Effects of resistance exercise combined with moderate vascular occlusion on muscular function in humans.</a> <em style='font-style: italic'>J. Appl. Physiol</em>. <b>88</b>, 2097-2106 (2000).</li></ol>

<p class="jove_content">我们提出了一个新颖，有可能是第一，非药理治疗手段能够抵消的，通常发生在患者与IBM的常规治疗下的肌肉萎缩和力量的下降。阻力血管闭塞的培训是一个相对较新的训练方法，但结果是非常令人鼓舞的的。我们发现，经过12周的培训计划，按IBM病人的腿重复最多，平衡和流动性的功能，及大腿的截面积分别增加15.9％，60％和4.7％。健康调查问卷分量表表明，改进范围从18％到600％和mechanogrowth?...

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<td>Vascular Doppler</td>
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<td>Two customized tourniquets cuffs with pressure manometers</td>
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<td>Conventional blood pressure cuff</td>
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<td>Leg extension machine</td>
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vascular occlusion training for inclusion body myositis: a novel therapeutic approach

<p class="jove_content">包涵体肌炎（IBM）是一种罕见的特发性炎性肌病。据了解，产生显着的肌肉无力和功能和生活质量大大妥协。此外，临床实践表明，不同于其他炎性肌病，大多数IBM的患者没有反应与免疫抑制或免疫调节药物治疗，以对付疾病的进展<sup&gt; 1</sup&gt;。此外，传统的阻力训练计划已被证明无效恢复在这些患者中的肌肉功能和肌肉质量<sup&gt; 2,3</sup&gt;。然而，我们最近观察到，限制肌血流量中等强度的阻力训练在IBM患者使用止血带协会袖口产生的肌肉质量和功能的显着增益，伴随着实实在在的好处，生活质量<sup&gt; 4</sup&gt;。因此，一个新的非药物方法为IBM患者已被提出。在这里，我们描述了一个对这个群体的阻力训练计划相关的血管闭塞提议的协议的细节。</p>

Watch this Scientific Journal Video about Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach at JoVE.com

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach

<p class="jove_content">本文章介绍有关的细节，以应用在IBM患者血管闭塞相关的阻力训练。</p>

血管闭塞包涵体肌炎培训：一种新的治疗方法

Inclusion body myositis (IBM) is a rare idiopathic inflammatory myopathy. It is known to produces remarkable muscle weakness and to greatly compromise ...

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