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Surface Plasmon Resonance (SPR) for Evaluating PROTACS-Induced Ternary Complex Formation

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03:36 min

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January 12th, 2024

DOI :

10.3791/200656-v

January 12th, 2024

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1Center for the Development of Therapeutics, The Broad Institute of MIT and Harvard

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Surface Plasmon Resonance SPR
PROTACS
Ternary Complex Formation
VHL
MZ1
BRD4
Binary Complex
Ternary Complex
Cooperativity
Cereblon
PPM1D
Nickel NTA Chip
Regeneration

From the series

Characterization of Ternary Complex Formation in PROTACs Using Biophysical Assays
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