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Mouse Cisterna Magna (CM) Injection Procedure to Study Elastase-Induced Vessel Dilatation in CNS Disorders

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01:58 min

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May 17th, 2024

DOI :

10.3791/201847-v

May 17th, 2024

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Dominic Simpson¹^,², Christopher D. Morrone¹, Darcy Wear¹^,², Jose Gutierrez³, Wai Haung Yu²

¹Brain Health Imaging Centre, Centre for Addiction and Mental Health, ²Department of Pharmacology and Toxicology, University of Toronto, ³Department of Neurology, Columbia University

Transcript

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Mouse Injection Procedure

Elastase induced Vessel Dilatation

Anesthetized Mouse

Ophthalmic Ointment

Metacam Injection

Saline Subcutaneous Injection

Stereotaxic Frame

Surgical Site Preparation

Scalpel Incision

Hamilton Syringe

Cerebrospinal Fluid CSF

Non absorbable Surgical Suture

Recovery Process

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