Name: brain imaging investigation of the memory-enhancing effect of emotion
Uploaded: 2011-05-04T13:00:00
Description: Watch this Scientific Journal Video about Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion at JoVE.com

FD fick stöd av en Young Investigator Award från National Alliance för forskning om schizofreni och depression samt en CPRF Award från den kanadensiska Psychiatric Research Foundation.

1. Experimentell design, metodfrågor, och Stimuli SMP består av två uppgifter, en kodning uppgift och en hämtning uppgift, och registrering av hjärnans aktivitet kan förekomma under kodningen uppgiften eller under både kodning och uppgifter hämtning (se figur 1 för ett diagram som illustrerar utformningen av SMP). <img src="/files/ftp_upload/2433/2433fig1.jpg" alt="Figur 1" /> Figur 1. Allmänna Diagram av SMP design. Hjärnan vars ve...

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Denna experimentella protokollet möjliggör undersökning av neurala korrelat av minnet som förbättrar effekten av känslor, genom att specifikt skilja minnet-relaterade hjärnaktivitet som är mottagliga för modulering av känslor från aktivitet i hjärnan känsliga för känslor modulering under allmänt / perceptuella bearbetning. Denna design har varit avgörande för att öka kunskaperna om de neurala mekanismerna bakom effekten av känslor på minnet, och med tanke på dess mångsidighet det förväntas att S...

brain imaging investigation of the memory-enhancing effect of emotion

Känslomässiga händelser tenderar att vara bättre ihågkommen än icke-emotionella händelser 1,2. Ett mål av kognitiva och affektiva neuroforskare är att förstå de neurala mekanismerna bakom detta ökad påverkan av känslor på minnet. En metod som har visat sig särskilt inflytelserika i utredningen av minnet som förbättrar effekten av känslor är den så kallade efterföljande minne paradigm (SMP). Denna metod användes ursprungligen för att undersöka neurala korrelat av icke-emotionella minnen 3, och på senare tid vi och andra tillämpas även den framgångsrikt till studier av emotionella minne (över 4, 5-7). Här beskriver vi ett protokoll som gör undersökning av neurala korrelat av minnet som förbättrar effekten av känslor med hjälp av SMP i samband med event-relaterade funktionell magnetresonanstomografi (fMRI). Ett viktigt inslag i SMP är att det tillåter separation av hjärnans aktivitet specifikt i samband med minnet från mer allmänna verksamhet i samband med perception. Dessutom i samband med att studera betydelsen av känslomässiga stimuli, kan SMP identifiering av områden i hjärnan vars verksamhet mottagliga för emotionella modulering av både allmän / perceptuella och minne-specifik behandling. Detta protokoll kan användas på friska försökspersoner 8-15, samt i kliniska patienter där det finns förändringar i neurala korrelat av känslor uppfattning och fördomar i minnas känslomässiga händelser, såsom de som lider av depression och posttraumatiskt stressyndrom (PTSD ) 16, 17.

Watch this Scientific Journal Video about Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion at JoVE.com

Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion

Vi presenterar ett protokoll som använder funktionell magnetisk resonanstomografi att undersöka neurala korrelat till minnet som förbättrar effekten av känslor. Detta protokoll möjliggör identifiering av hjärnans aktivitet specifikt kopplade till minne-relaterade bearbetning, i motsats till mer allmänna perceptuella behandling, och kan användas med friska och kliniska populationer.

Brain Imaging Utredning av Memory-ökad påverkan av Emotion

Emotional events tend to be better remembered than non-emotional events1,2. One goal of cognitive and affective neuroscientists is 
to understand the ...

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