Name: brain imaging investigation of the memory-enhancing effect of emotion
Uploaded: 2011-05-04T13:00:00
Description: Watch this Scientific Journal Video about Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion at JoVE.com

FD Genç Araştırmacı Ödülü, Araştırma ve Şizofreni ve Depresyon CPRF Kanada Psikiyatrik Araştırma Vakfı Ödülü için Ulusal İttifak tarafından desteklenen oldu.

1. Deneysel Tasarım, Metodolojik Sorunları &amp; Uyaranlar SMP kodlama görev sırasında veya kodlama ve geri alma görevleri (SMP tasarımı gösteren bir diyagram için bkz. Şekil 1) sırasında oluşabilir iki görev, bir kodlama görev ve alma görev ve beyin aktivitesi kayıt oluşur. <img src="/files/ftp_upload/2433/2433fig1.jpg" alt="Şekil 1" /> Şekil 1 SMP tasarım Genel Diyagramı. Faaliyet kodlaması sırasında beyin bölgeler...

<ol>
	<li>Bradley, M. M., Greenwald, M. K., Petry, M. C., Lang, P. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Remembering+pictures:+pleasure+and+arousal+in+memory.">Remembering pictures: pleasure and arousal in memory.</a> J Exp Psychol Learn Mem Cogn. 18, 379-390 (1992).</li><li>Christianson, S. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Emotional+stress+and+eyewitness+memory:+a+critical+review.">Emotional stress and eyewitness memory: a critical review.</a> Psychol Bull. 112, 284-309 (1992).</li><li>Paller, K. A., Wagner, A. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Observing+the+transformation+of+experience+into+memory.">Observing the transformation of experience into memory.</a> Trends Cogn Sci. 6, 93-102 (2002).</li><li>Dolcos, F. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=.">.</a> The Impact of Emotion on Memory: Evidence from Brain Imaging Studies. , (2009).</li><li>Dolcos, F., Denkova, E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Neural+correlates+of+encoding+emotional+memories:+a+review+of+functional+neuroimaging+evidence.">Neural correlates of encoding emotional memories: a review of functional neuroimaging evidence.</a> Cell Science Reviews. 5, 78-122 (2008).</li><li>Dolcos, F., LaBar, K. S., Cabeza, R., Uttl, B., Ohta, N. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+memory-enhancing+effect+of+emotion:+Functional+neuroimaging+evidence.">The memory-enhancing effect of emotion: Functional neuroimaging evidence.</a> Memory and Emotion: Interdisciplinary Perspectives. , 107-134 (2006).</li><li>LaBar, K. S., Cabeza, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Cognitive+neuroscience+of+emotional+memory.">Cognitive neuroscience of emotional memory.</a> Nat Rev Neurosci. 7, 54-64 (2006).</li><li>Dolcos, F., Cabeza, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Event-related+potentials+of+emotional+memory:+encoding+pleasant,+unpleasant,+and+neutral+pictures.">Event-related potentials of emotional memory: encoding pleasant, unpleasant, and neutral pictures.</a> Cogn Affect Behav Neurosci. 2, 252-263 (2002).</li><li>Dolcos, F., Graham, R., LaBar, K. S., Cabeza, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Coactiviation+of+the+amygdala+and+hippocampus+predicts+better+recall+for+emotional+than+for+neutral+pictures.">Coactiviation of the amygdala and hippocampus predicts better recall for emotional than for neutral pictures.</a> Brain &#38; Cognition. 51, 221-223 (2003).</li><li>Dolcos, F., LaBar, K. S., Cabeza, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Dissociable+effects+of+arousal+and+valence+on+prefrontal+activity+indexing+emotional+evaluation+and+subsequent+memory:+an+event-related+fMRI+study.">Dissociable effects of arousal and valence on prefrontal activity indexing emotional evaluation and subsequent memory: an event-related fMRI study.</a> Neuroimage. 23, 64-74 (2004).</li><li>Dolcos, F., LaBar, K. S., Cabeza, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Interaction+between+the+amygdala+and+the+medial+temporal+lobe+memory+system+predicts+better+memory+for+emotional+events.">Interaction between the amygdala and the medial temporal lobe memory system predicts better memory for emotional events.</a> Neuron. 42, 855-863 (2004).</li><li>Dolcos, F., LaBar, K. S., Cabeza, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Remembering+one+year+later:+role+of+the+amygdala+and+the+medial+temporal+lobe+memory+system+in+retrieving+emotional+memories.">Remembering one year later: role of the amygdala and the medial temporal lobe memory system in retrieving emotional memories.</a> Proc Natl Acad Sci U S A. 102, 2626-2631 (2005).</li><li>Ritchey, M., Dolcos, F., Cabeza, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Role+of+amygdala+connectivity+in+the+persistence+of+emotional+memories+over+time:+an+event-related+FMRI+investigation.">Role of amygdala connectivity in the persistence of emotional memories over time: an event-related FMRI investigation.</a> Cereb Cortex. 18, 2494-2504 (2008).</li><li>Jacques, S. t., Dolcos, P. L., Cabeza, F., R, . <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Effects+of+aging+on+functional+connectivity+of+the+amygdala+for+subsequent+memory+of+negative+pictures:+a+network+analysis+of+functional+magnetic+resonance+imaging+data.">Effects of aging on functional connectivity of the amygdala for subsequent memory of negative pictures: a network analysis of functional magnetic resonance imaging data.</a> Psychol Sci. 20, 74-84 (2009).</li><li>Jacques, S. t., Dolcos, P., Cabeza, F., R, . <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Effects+of+aging+on+functional+connectivity+of+the+amygdala+during+negative+evaluation:+a+network+analysis+of+fMRI+data.">Effects of aging on functional connectivity of the amygdala during negative evaluation: a network analysis of fMRI data.</a> Neurobiol Aging. 31, 315-327 (2010).</li><li>Hayes, J. P., LaBar, K. S., McCarthy, G. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Reduced+hippocampal+and+amygdala+activity+predicts+memory+distrotions+for+trauma+reminders+in+combat-related+PTSD.">Reduced hippocampal and amygdala activity predicts memory distrotions for trauma reminders in combat-related PTSD.</a> J Psychiatr Res. , (2011).</li><li>Ritchey, M., Dolcos, F., Eddington, K. M., Strauman, T. J., Cabeza, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Neural+correlates+of+emotional+processing+in+depression:+Changes+with+cognitive+behavioral+therapy+and+predictors+of+treatment+response.">Neural correlates of emotional processing in depression: Changes with cognitive behavioral therapy and predictors of treatment response.</a> Journal of Psychiatric Research. , (2010).</li><li>Kleinsmith, L. J., Kaplan, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Paired-associate+learning+as+a+function+of+arousal+and+interpolated+interval.">Paired-associate learning as a function of arousal and interpolated interval.</a> J Exp Psychol. 65, 190-193 (1963).</li><li>Kensinger, E. A., Schacter, D. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Amygdala+activity+is+associated+with+the+successful+encoding+of+item,+but+not+source,+information+for+positive+and+negative+stimuli.">Amygdala activity is associated with the successful encoding of item, but not source, information for positive and negative stimuli.</a> J Neurosci. 26, 2564-2570 (2006).</li><li>Kensinger, E. A., Corkin, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Two+routes+to+emotional+memory:+distinct+neural+processes+for+valence+and+arousal.">Two routes to emotional memory: distinct neural processes for valence and arousal.</a> Proc Natl Acad Sci U S A. 101, 3310-3315 (2004).</li><li>Kensinger, E. A., Garoff-Eaton, R. J., Schacter, D. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Memory+for+specific+visual+details+can+be+enhanced+by+negative+arousing+content.">Memory for specific visual details can be enhanced by negative arousing content.</a> Journal of Memory and Language. 54, 99-112 (2006).</li><li>Bradley, M. M., Cuthbert, B. N., Lang, P. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Picture+media+and+emotion:+effects+of+a+sustained+affective+context.">Picture media and emotion: effects of a sustained affective context.</a> Psychophysiology. 33, 662-670 (1996).</li><li>Lang, P. J., Bradley, M. M., Cuthbert, B. N. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Technical+Report+A-8.">Technical Report A-8.</a> International affective picture system (IAPS): Affective ratings of pictures and instruction manual. , (2008).</li><li>Lang, P. J., Bradley, M. M., Cuthbert, B. N. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Technical+report+C-1.">Technical report C-1.</a> Affective norms for English workds (ANEW): Stimuli, instruction manual and affective ratings. , (2008).</li><li>Bradley, M. M., Lang, P. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Measuring+emotion:+the+Self-Assessment+Manikin+and+the+Semantic+Differential.">Measuring emotion: the Self-Assessment Manikin and the Semantic Differential.</a> J Behav Ther Exp Psychiatry. 25, 49-59 (1994).</li><li>Kensinger, E. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Remembering+emotional+experiences:+the+contribution+of+valence+and+arousal.">Remembering emotional experiences: the contribution of valence and arousal.</a> Rev Neurosci. 15, 241-251 (2004).</li><li>Hamann, S. B., Ely, T. D., Grafton, S. T., Kilts, C. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Amygdala+activity+related+to+enhanced+memory+for+pleasant+and+aversive+stimuli.">Amygdala activity related to enhanced memory for pleasant and aversive stimuli.</a> Nat Neurosci. 2, 289-293 (1999).</li><li>Watson, D., Clark, L. A., Tellegen, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Development+and+validation+of+brief+measures+of+positive+and+negative+affect:+the+PANAS+scales.">Development and validation of brief measures of positive and negative affect: the PANAS scales.</a> J Pers Soc Psychol. 54, 1063-1070 (1988).</li><li>Spielberger, C. D., Gorsuch, R. L., Lushene, R. E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=.">.</a> Manual for the State-Trait Anxiety Inventory. , (1970).</li><li>Voyvodic, J. T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Real-Time+fMRI+Paradigm+Control,+Physiology,+and+Behavior+Combined+with+Near+Real-Time+Statistical+Analysis.">Real-Time fMRI Paradigm Control, Physiology, and Behavior Combined with Near Real-Time Statistical Analysis.</a> NeuroImage. 10, 91-106 (1999).</li><li>Tulving, E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Memory+and+consciousness.">Memory and consciousness.</a> Canadian Psychology. 26, 1-12 (1985).</li><li>Eldridge, L. L., Knowlton, B. J., Furmanski, C. S., Bookheimer, S. Y., Engel, S. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Remembering+episodes:+a+selective+role+for+the+hippocampus+during+retrieval.">Remembering episodes: a selective role for the hippocampus during retrieval.</a> Nat Neurosci. 3, 1149-1152 (2000).</li><li>Kirwan, C. B., Jones, C. K., Miller, M. I., Stark, C. E. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=High-resolution+fMRI+investigation+of+the+medial+temporal+lobe.">High-resolution fMRI investigation of the medial temporal lobe.</a> Human Brain Mapping. 28, 959-966 (2007).</li><li>Preston, A. R., Bornstein, A. M., Hutchinson, J. B., Gaare, M. E., Glover, G. H., Wagner, A. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=High-resolution+fMRI+of+Content-sensitive+Subsequent+Memory+Responses+in+Human+Medial+Temporal+Lobe.">High-resolution fMRI of Content-sensitive Subsequent Memory Responses in Human Medial Temporal Lobe.</a> Journal of Cognitive Neuroscience. 22, 156-173 (2010).</li><li>Robinson, S., Pripfl, J., Bauer, H., Moser, E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+impact+of+EPI+voxel+size+on+SNR+and+BOLD+sensitivity+in+the+anterior+medio-temporal+lobe:+a+comparative+group+study+of+deactivation+of+the+Default+Mode.">The impact of EPI voxel size on SNR and BOLD sensitivity in the anterior medio-temporal lobe: a comparative group study of deactivation of the Default Mode.</a> Magnetic Resonance Materials in Physics, Biology and Medicine. 21, 279-290 (2008).</li><li>Daselaar, S. M., Fleck, M. S., Cabeza, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Triple+Dissociation+in+the+Medial+Temporal+Lobes:+Recollection,+Familiarity,+and+Novelty.">Triple Dissociation in the Medial Temporal Lobes: Recollection, Familiarity, and Novelty.</a> Journal of Neurophysiology. 96, 1902-1911 (2006).</li><li>McGaugh, J. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Memory--a+century+of+consolidation.">Memory--a century of consolidation.</a> Science. 287, 248-251 (2000).</li><li>McGaugh, J. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+amygdala+modulates+the+consolidation+of+memories+of+emotionally+arousing+experiences.">The amygdala modulates the consolidation of memories of emotionally arousing experiences.</a> Annu Rev Neurosci. 27, 1-28 (2004).</li></ol>

Bu deneysel protokol genel / algısal işleme sırasında duygu modülasyon duyarlı beyin bölgelerinde faaliyet duygu modülasyon duyarlı hafıza ile ilgili beyin aktivitesinin özellikle ayırarak, duygu belleği arttırıcı etkisi sinirsel ilgisi soruşturma sağlar. Bu tasarım bellek duygunun etkisi altında yatan nöral mekanizmalar anlayışımıza ilerleyen enstrümantal ve bu SMP bir olay yaşamış. Anda mevcut çeşitli yönlerini daha sonra bir etkileyebilir olacak nasıl belirleyen önemli kalır olacak ...

brain imaging investigation of the memory-enhancing effect of emotion

Duygusal olaylar-duygusal olmayan olaylar 1,2 &#39;den daha iyi hatırlanması gereken eğilimindedir . Bilişsel ve duyuşsal Nörobilimadamları Bir gol hafıza duygu bu artırıcı etkisi altında yatan nöral mekanizmalarını anlamak için. Özellikle etkili soruşturma duygu belleği arttırıcı etkisi kanıtlanmış olan bir yöntemi olarak adlandırılan bir sonraki bellek paradigması (SMP). Bu yöntem başlangıçta sinirsel ilgisi olmayan duygusal anılar 3 araştırmak için kullanılan ve daha yakın zamanda biz ve diğerleri de duygusal bellek (5-7 4, gözden) çalışmaları başarılı bir şekilde uygulanmış. Burada, biz izin veren bir protokol tarif SMP ile birlikte olay ile ilgili fonksiyonel manyetik rezonans görüntüleme (fMRI) kullanarak duygu belleği arttırıcı etkisi sinir ögelerinden incelenmesi. SMP önemli bir özelliği de özellikle algı ile ilgili daha genel faaliyet hafıza ile ilgili beyin aktivitesini ayırma izin vermesidir. Ayrıca, duygusal uyaranların etkisi araştıran bağlamda, SMP aktivite genel / algısal ve hafıza özgü işleme duygusal modülasyon duyarlı olan beyin bölgeleri belirlenmesi sağlar. Bu protokol yanı sıra, değişiklikler gibi depresyon ve post-travmatik stres bozukluğu (TSSB olanlara gibi duygusal olaylar, hatırlamak, duygu algılama ve önyargıların sinirsel ilgisi vardır hastaların klinik, sağlıklı kişilerde 8-15 kullanılabilir ) 16, 17.

Watch this Scientific Journal Video about Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion at JoVE.com

Brain Imaging Investigation of the Memory-Enhancing Effect of Emotion

Biz, duygu belleği arttırıcı etkisi sinirsel ilgisi araştırmak için fonksiyonel manyetik rezonans görüntüleme kullanan bir protokol mevcut. Bu protokol, daha genel bir algısal işleme aykırı bellekle ilgili işleme, özellikle bağlantılı beyin aktivitesinin belirlenmesi sağlar ve sağlıklı ve klinik nüfus ile kullanılabilir.

Duygu Bellek Artırıcı Etkisi Beyin Görüntüleme İncelenmesi

Emotional events tend to be better remembered than non-emotional events1,2. One goal of cognitive and affective neuroscientists is 
to understand the ...

Research

JoVE Journal

Neuroscience

Brain Imaging Investigation of the Neural Correlates of Observing Virtual Social Interactions

Sanal Sosyal Etkileşimleri Gözlem Sinir Bağlantılı Beyin Görüntüleme İncelenmesi

The ability to gauge social interactions is crucial in the assessment of others&#x2019; intentions. Factors such as facial expressions and body language ...

Brain Imaging Investigation of the Neural Correlates of Emotional Autobiographical Recollection

Duygusal Otobiyografik Anımsama Sinir Bağlantılı Beyin Görüntüleme İncelenmesi

Recollection of emotional autobiographical memories (AMs) is important to healthy cognitive and affective functioning 1 - remembering positive AMs is ...

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation

Emotion Yönetmeliği&#39;nin Sinir Bağlantılı Beyin Görüntüleme İncelenmesi

The ability to control/regulate emotions is an important coping mechanism in the face of emotionally stressful situations. Although significant progress ...

Brain Imaging Investigation of the Impairing Effect of Emotion on Cognition

Biliş üzerine Duygu bozarak Etkisi Beyin Görüntüleme İncelenmesi

Emotions can impact cognition by exerting both enhancing (e.g., better memory for emotional events) and impairing (e.g., increased emotional ...

Enabling High Grayscale Resolution Displays and Accurate Response Time Measurements on Conventional Computers

Etkinleştirilmesi Yüksek Çözünürlük görüntüler ve Konvansiyonel Bilgisayarlara Doğru Tepki Süresi Ölçümleri Grayscale

Display systems based on conventional computer graphics cards are capable of generating images with 8-bit gray level resolution. However, most experiments ...

Live Imaging of Mitosis in the Developing Mouse Embryonic Cortex

Gelişmekte Fare Embriyonik Cortex mitoz Canlı Görüntüleme

Although of short duration, mitosis is a complex and dynamic multi-step process fundamental for development of organs including the brain. In the ...

Live Imaging of the Ependymal Cilia in the Lateral Ventricles of the Mouse Brain

Fare Beyin lateral ventrikül Ependimal Cilia Canlı Görüntüleme

Multiciliated ependymal cells line the ventricles in the adult brain. Abnormal function or structure of ependymal cilia is associated with various ...

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex

Hücresel Örgütü fare yeni korteksimiz yılında büyük ölçekli üç boyutlu görüntüleme

The mammalian neocortex is composed of many types of excitatory and inhibitory neurons, each with specific electrophysiological and biochemical ...

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury

Hafif Travmatik Beyin Hasarı Olan Sıçanların Hipokampuslarında İleri Difüzyon Görüntüleme

Mild traumatic brain injury (mTBI) is the most common type of acquired brain injury. Since patients with traumatic brain injury show a tremendous ...

Investigation of Spatial Interaction Between Astrocytes and Neurons in Cleared Brains

Temizlenmiş Beyinlerde Astrositler ve Nöronlar Arasındaki Mekansal Etkileşimin İncelenmesi

Combining viral vector transduction and tissue clearing using the CLARITY method makes it possible to simultaneously investigate several types of brain ...