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Generation of Multivirus-specific T Cells to Prevent/treat Viral Infections after Allogeneic Hematopoietic Stem Cell Transplant

DOI :

10.3791/2736-v

8:52 min

May 27th, 2011

May 27th, 2011

16,783 Views

1Center for Cell and Gene Therapy, Baylor College of Medicine

A rapid, simple and cost-effective protocol for the generation of donor-derived multivirus-specific CTLs (rCTL) for infusion to allogeneic hematopoietic stem cell transplant (HSCT) recipients at risk of developing CMV, Adv or EBV infections. This manufacturing process is GMP-compliant and should ensure the broader implementation of T-cell immunotherapy beyond specialized centers.

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Multivirus specific T Cells

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