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DOI :
10.3791/2911-v
•
11:10 min
August 28th, 2011
Chapters
0:05
Title
1:50
Preparation of Lung Tissue Strips
3:11
AFM Microindentation and Fluorescent Imaging
7:14
AFM Data Extraction
8:48
Representative AFM Results
10:48
Conclusion
細胞外マトリックスの剛性が強く、接着細胞の複数の動作に影響を与えます。マトリックスの剛性は、組織全体に空間的に変化し、様々な疾患状態の修正を受ける。ここでは、原子間力顕微鏡のmicroindentationを使用して、通常と線維化マウスの肺組織における剛性の空間的な変動を特徴付けるための方法を開発する。
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