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DOI :
10.3791/3661-v
February 17th, 2012
Chapters
0:05
Title
1:57
Preparation of Mammary Architecture and Microenvironment Engineering (MAME) Cocultures
4:08
Performing 4D (3D + time) Imaging of Live MAME Cocultures by Confocal Microscopy
5:11
Representative 4D MAME Live-cell Imaging Models
7:57
Conclusion
我々は侵襲的な表現型への微小環境に影響を与える進行中の乳房の腫瘍細胞と他の細胞間の相互作用をリアルタイムでライブセルイメージングのための3D共培養モデルを開発しました。これらのモデルは、パラクリン誘起分解、ケモカイン/サイトカインと侵襲性に関与するキナーゼ経路を標的とする薬剤の臨床画面として使用できます。
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