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基于DNA载体的RNA干扰在癌症研究基因功能

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June 4th, 2012

June 4th, 2012

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Daniel B. Stovall¹, Meimei Wan¹, Qiang Zhang¹, Purnima Dubey², Guangchao Sui¹

¹Department of Cancer Biology and Comprehensive Cancer Center, Wake Forest University School of Medicine, ²Department of Pathology and Comprehensive Cancer Center, Wake Forest University School of Medicine

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RNA干扰（RNAi）拥有超过基因敲除的许多优点，在基因功能研究的工具已被广泛使用。基于DNA载体的RNAi技术的发明，已作出长期和诱导基因敲除可能，也增加了基因沉默的可行性在体内。

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