Name: functional magnetic resonance imaging (fmri) with auditory stimulation in songbirds
Uploaded: 2013-06-03T08:56:00
Description: Watch this Scientific Journal Video about Functional Magnetic Resonance Imaging fMRI with Auditory Stimulation in Songbirds at JoVE.com

Bu araştırma, Araştırma Vakfı hibe tarafından desteklenmiştir - Flanders (FWO, proje No G.0420.02 ve G.0443.11N), Antwerp Üniversitesi&#39;nden Hercules Vakfı (hibe No AUHA0012), Uyumlu Araştırma İşlemleri (GOA finansman) ve kısmen Avrupa Komisyonu tarafından desteklenen - FP6 proje dimi, LSHB-CT-2005-512146 ve EC - 6. ÇP proje EMIL A.VdL için LSHC-CT-2004-503569. Flanders (FWO) - G.DG ve CP Araştırma Vakfı Doktora Sonrası Fellows vardır.

1. İşitsel Uyarılar hazırlanması <ol><li> 7T MR sisteminin delik içinde oynadı olurken ses uyaranlara kayıt İlk. Delik bazı işitsel frekansları geliştirme sonuçlanan işitsel uyaranlara bozabilir kapalı bir alandır. Şekil 1 geliştirilmiş ve gibi mıknatıs içinde kuş başının yerde yapılan beyaz gürültü bizim kayıtları gösterdiği bastırılmış frekansları bir kullanarak delik gösterir fiber optik mikrofon (Optimic 1160, Optoacoustics). Bu yapay geliştirme telafi etm...

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M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Spin+echo+BOLD+fMRI+on+songbirds.">Spin echo BOLD fMRI on songbirds.</a> Methods Mol. 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Q., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Microvascular+BOLD+contribution+at+4+and+7+T+in+the+human+brain:+gradient-echo+and+spin-echo+fMRI+with+suppression+of+blood+effects.">Microvascular BOLD contribution at 4 and 7 T in the human brain: gradient-echo and spin-echo fMRI with suppression of blood effects.</a> Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 49, 1019-1027 (2003).</li><li>Lee, S. P., Silva, A. C., Ugurbil, K., Kim, S. G. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Diffusion-weighted+spin-echo+fMRI+at+9.4+T:+microvascular/tissue+contribution+to+BOLD+signal+changes.">Diffusion-weighted spin-echo fMRI at 9.4 T: microvascular/tissue contribution to BOLD signal changes.</a> Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 42, 919-928 (1999).</li><li>Uludag, K., Muller-Bierl, B., Ugurbil, K. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=An+integrative+model+for+neuronal+activity-induced+signal+changes+for+gradient+and+spin+echo+functional+imaging.">An integrative model for neuronal activity-induced signal changes for gradient and spin echo functional imaging.</a> NeuroImage. 48, 150-165 (2009).</li><li>Yacoub, E., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Spin-echo+fMRI+in+humans+using+high+spatial+resolutions+and+high+magnetic+fields.">Spin-echo fMRI in humans using high spatial resolutions and high magnetic fields.</a> Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 49, 655-664 (2003).</li><li>Keilholz, S. D., Silva, A. C., Raman, M., Merkle, H., Koretsky, A. P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Functional+MRI+of+the+rodent+somatosensory+pathway+using+multislice+echo+planar+imaging.">Functional MRI of the rodent somatosensory pathway using multislice echo planar imaging.</a> Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 55, 316-324 (2006).</li><li>Keilholz, S. D., Silva, A. C., Raman, M., Merkle, H., Koretsky, A. 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P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=BOLD+fMRI+and+somatosensory+evoked+potentials+are+well+correlated+over+a+broad+range+of+frequency+content+of+somatosensory+stimulation+of+the+rat+forepaw.">BOLD fMRI and somatosensory evoked potentials are well correlated over a broad range of frequency content of somatosensory stimulation of the rat forepaw.</a> Brain Research. 1195, 67-76 (2008).</li><li>Kida, I., Yamamoto, T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Stimulus+frequency+dependence+of+blood+oxygenation+level-dependent+functional+magnetic+resonance+imaging+signals+in+the+somatosensory+cortex+of+rats.">Stimulus frequency dependence of blood oxygenation level-dependent functional magnetic resonance imaging signals in the somatosensory cortex of rats.</a> Neuroscience Research. 62, 25-31 (2008).</li><li>Poirier, C., Boumans, T., Verhoye, M., Balthazart, J., Van der Linden, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Own-song+recognition+in+the+songbird+auditory+pathway:+selectivity+and+lateralization.">Own-song recognition in the songbird auditory pathway: selectivity and lateralization.</a> The Journal of Neuroscience: The Official Journal of the Society for Neuroscience. 29, 2252-2258 (2009).</li><li>Poirier, C., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Own+song+selectivity+in+the+songbird+auditory+pathway:+suppression+by+norepinephrine.">Own song selectivity in the songbird auditory pathway: suppression by norepinephrine.</a> PloS ONE. 6, e20131 (2011).</li><li>Logothetis, N. 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Bu yazıda, anestezi zebra ispinoz işitsel uyarım nöral yüzeylerde in vivo karakterizasyonu ayrıntılı için optimize edilmiş bir protokol açıklar. Sunulan protokol doğrultusunda, BOLD fMRI kullanarak hayvanlarda fonksiyonel beyin aktivasyon çalışmaların çoğunluğu, satın alma sırasında hayvanların uyuşturan. Çalışma dönemlerinde mıknatıs çevre ve tarayıcı gürültü onları alıştırmak için eğitim hayvanlar da zaman alıcı ve zor ve bu nedenle nad...

<table border="1">
 <tbody>
 <tr>
 <td>Name of the reagent/equipment</td>
 <td>Company</td>
 <td>Catalogue number</td>
 <td>Comments </td>
 </tr>
 <tr>
 <td>Isoflurane anaesthetic</td>
 <td>Isoflo</td>
 <td>05260-05</td>
 <td></td>
 </tr>
 <tr>
 <td>PC-Sam hardware/software</td>
 <td>SA-Instruments</td>
 <td></td>
 <td><a href="http://www.i4sa.com" target="_blank">http://www.i4sa.com</a></td>
 </tr>
 <tr>
 <td>Monitoring and gating system</td>
 <td></td>
 <td>1025</td>
 <td></td>
 </tr>
 <tr>
 <td>MR-compatible small rodent heater system</td>
 <td></td>
 <td></td>
 <td>Model 1025 compatible</td>
 </tr>
 <tr>
 <td>Rectal temperature probe</td>
 <td></td>
 <td>RTP-102B</td>
 <td>7'', 0.044'' </td>
 </tr>
 <tr>
 <td>7T MR scanner</td>
 <td>Bruker Biospin</td>
 <td>PHS 70/16 </td>
 <td></td>
 </tr>
 <tr>
 <td>Paravision software</td>
 <td></td>
 <td>5.1</td>
 <td></td>
 </tr>
 <tr>
 <td>Gradient Insert</td>
 <td></td>
 <td>BGA9S</td>
 <td>400 mT/m, 300A, 500V</td>
 </tr>
 <tr>
 <td>Gradient Amplifiers</td>
 <td>Copley Co., USA</td>
 <td>C256</td>
 <td></td>
 </tr>
 <tr>
 <td>Transmit resonators</td>
 <td></td>
 <td></td>
 <td>Inner diameter: 72 mm, transmit only, active decoupled</td>
 </tr>
 <tr>
 <td>Receiver antenna - 20 mm quadrature Mouse Head</td>
 <td></td>
 <td></td>
 <td>Receive only, active decoupled</td>
 </tr>
 <tr>
 <td>WaveLab software</td>
 <td>Steinberg</td>
 <td></td>
 <td></td>
 </tr>
 <tr>
 <td>Praat software</td>
 <td>Paul Boersma, University of Amsterdam</td>
 <td></td>
 <td><a href="http://www.praat.org" target="_blank">http://www.praat.org</a></td>
 </tr>
 <tr>
 <td>Non-magnetic dynamic speakers</td>
 <td>Visation, Germany</td>
 <td>HK 150</td>
 <td></td>
 </tr>
 <tr>
 <td>Fiber optic microphone</td>
 <td>Optoacoustics, </td>
 <td>Optimic 1160</td>
 <td></td>
 </tr>
 <tr>
 <td>Sound amplifier</td>
 <td>Phonic corporation</td>
 <td>MM 1002a</td>
 <td></td>
 </tr>
 <tr>
 <td>Presentation software</td>
 <td>Neurobehavioral Systems Inc.</td>
 <td></td>
 <td></td>
 </tr>
 <tr>
 <td>MRIcro</td>
 <td>Chris Rorden</td>
 <td></td>
 <td><a href="http://www.cabiatl.com/mricro/mricro/" target="_blank">http://www.cabiatl.com/mricro/mricro/</a></td>
 </tr>
 <tr>
 <td>Statistical Parametric Mapping (SPM)</td>
 <td>Welcome Trust Centre for Neuroimaging</td>
 <td>8</td>
 <td><a href="http://www.fil.ion.ucl.ac.uk/spm/" target="_blank">http://www.fil.ion.ucl.ac.uk/spm/</a></td>
 </tr>
 </tbody>
</table>

functional magnetic resonance imaging (fmri) with auditory stimulation in songbirds

Birdsong nörobiyoloji, insan konuşma için bir model olarak, davranışsal nörobilim araştırma belirgin bir alandır. Elektrofizyoloji ve moleküler yaklaşımlar az nöron ya da beyin, bağımlı kan oksijenlenme seviyesi (BOLD) fonksiyonel Manyetik Rezonans Görüntüleme (fMRI) büyük parçalar bir uyarıcı üzerinde ya farklı uyaranların soruşturma hem avantajları birleştirerek sağlar izin ise, nöral aktivasyon karşılaştırma yani bir kerede bütün beyin farklı uyarıcılara ile oluşmaktadır. ötücü fMRI çünkü beyinleri küçük boyutu ve kemikleri nedeniyle zordur ve özellikle kafatası önemli duyarlılık eserler neden olan, çok sayıda hava boşlukları oluşur. Gradient-eko (GE) BOLD fMRI başarıyla ötücü 1-5 (bir inceleme için, 6) uygulanmıştır. Bu çalışmalar duyarlılık eserler serbest bölgeleri olan birincil ve ikincil işitsel beyin alanları, odaklanmıştır. Ancak, Procilgi esses bu bölgelerde ötesinde oluşabilir, tüm beyin BOLD fMRI bu eserler daha az duyarlı bir MRI dizisi kullanılarak gereklidir. Bu spin eko (SE) koyu fMRI 7,8 kullanılarak elde edilebilir. Bu yazıda, yaygın kuşların cıvıl cıvıl davranışsal sinir bilimleri okudu 15-25 g vücut ağırlığı ile küçük ötücü kuşlar olan zebra ispinoz bu tekniğin (canlıdır Taeniopygia guttata), nasıl kullanılacağı açıklanmaktadır. Ötücü kuşlar üzerinde fMRI çalışmaları ana konusu şarkı algı ve şarkı öğrenmedir. SE zayıf BOLD hassasiyeti (GE göre) tabanlı fMRI dizileri bu tekniğin uygulanması çok zor yapar ile birlikte uyaranların işitsel doğası.

<html> Biz burada görsel olarak zebra ispinoz beyindeki işitsel uyaranların sinir yüzeylerde başarılı görüntüleme için prosedürlerin optimize edilmiş bir dizi sundu. İlk olarak, uyaranlara en işitsel uyaranlara sonuçlarının hazırlanması için açıklanan prosedür ON / blok paradigma OFF (Şekil 2) dahil edilebilir ve beyinde bir diferansiyel tepki uyandırmak olabilir ses basınç seviyesi potansiyel farklılıkları ortadan kaldırmak için normalize olduğunu . MRI tarama için zeb...

Watch this Scientific Journal Video about Functional Magnetic Resonance Imaging fMRI with Auditory Stimulation in Songbirds at JoVE.com

Functional Magnetic Resonance Imaging fMRI with Auditory Stimulation in Songbirds

Bu makalede, fonksiyonel Manyetik Rezonans Görüntüleme (fMRI) kullanarak ötücü kuş beyindeki işitsel uyarım nöral yüzeylerde görüntüleme için optimize edilmiş bir prosedürü gösterir. Bu ses uyaranlara, konunun konumlandırılması ve fMRI verilerinin elde edilmesi ve daha sonraki analiz hazırlanmasını tarif etmektedir.

Songbirds İşitsel Uyarım ile Fonksiyonel Manyetik Rezonans Görüntüleme (fMRI)

The neurobiology of birdsong, as a model for human speech, is a pronounced area of research in behavioral neuroscience. Whereas electrophysiology and ...

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Functional Magnetic Resonance Imaging (fMRI) with Auditory Stimulation in Songbirds

Best Current Practice for Obtaining High Quality EEG Data During Simultaneous fMRI

Eş zamanlı fMRI sırasında Yüksek Kalite EEG Veri alma için an En iyi Uygulama

Simultaneous  EEG-fMRI allows the excellent temporal resolution of EEG to be combined with the  high spatial accuracy of fMRI. The data  from these two ...

Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities

Engelli Çocuklarda Kortikal İşitsel-dokunsal İşleme Kantitatif Değerlendirilmesi

Objective and easy measurement of sensory processing is extremely difficult in nonverbal or vulnerable pediatric patients. We developed a new methodology ...

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Transkranial Manyetik Stimülasyon ile Dudak Motor Cortex Uyarıcı

Transcranial magnetic stimulation (TMS) has proven to be a useful tool in investigating the role of the articulatory motor cortex in speech perception. ...

Transcranial Direct Current Stimulation and Simultaneous  Functional Magnetic Resonance Imaging

Transkranyal Doğru Akım Uyarım ve Simultane Fonksiyonel Manyetik Rezonans Görüntüleme

Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation technique that uses weak electrical currents administered to the scalp ...

Transcranial Magnetic Stimulation for Investigating Causal Brain-behavioral Relationships and their Time Course

Nedensel Beyin-davranış İlişkiler ve Zaman Kursu araştırılması için Transkraniyal Manyetik Uyarım

Transcranial magnetic stimulation (TMS) is a safe, non-invasive brain stimulation technique that uses a strong electromagnet in order to temporarily ...

Transferring Cognitive Tasks Between Brain Imaging Modalities: Implications for Task Design and Results Interpretation in fMRI Studies

Beyin Görüntüleme Yöntemlerinin Arasında Bilişsel Görevler aktarma: fMRI Çalışmaları Görev Tasarım Etkileri ve Sonuçları Yorumlama

As cognitive neuroscience methods develop, established experimental tasks are used with emerging brain imaging modalities. Here transferring a paradigm ...

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

FMRI Çalışması Tasarım ve Uygulama Genç Kadınlarda Bastırma Düşünce ve At-risk Depresyon incelenmesi

Ruminative brooding is associated with increased vulnerability to major depression. Individuals who regularly ruminate will often try to reduce the ...

Multifunctional Setup for Studying Human Motor Control Using Transcranial Magnetic Stimulation, Electromyography, Motion Capture, and Virtual Reality

Transkraniyal Manyetik Uyarım, Elektromiyografi, Hareket Yakalama ve Sanal Gerçeklik kullanma İnsan Motor Kontrol incelenmesi için çok fonksiyonlu Kur

The study of neuromuscular control of movement in humans is accomplished with numerous technologies. Non-invasive methods for investigating neuromuscular ...

Neuronavigation-guided Repetitive Transcranial Magnetic Stimulation for Aphasia

Afazi için nöronavigasyon güdümlü Transkraniyal Manyetik Uyarım

Repetitive transcranial magnetic stimulation (rTMS) is widely used for several neurological conditions, as it has gained acknowledgement for its potential ...