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9.3K Views
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10:03 min
January 20th, 2014
DOI :
10.3791/50532-v
Chapters
0:05
Title
1:48
Assessment of Myogenic Potential
2:53
Transplantation in Mouse Models of Muscular Dystrophy
6:37
Outcome Measures on Transplanted Dystrophic Animals: Treadmill Test
8:15
Results: In vitro and In vivo Differentiation and Motor Capacity after Transplantation
9:24
Conclusion
Summary
誘導多能性幹細胞(iPSC)由来の筋原性前駆細胞は、筋ジストロフィーを治療するための細胞治療戦略の有望な候補である。このプロトコルは、急性および慢性筋肉再生のマウスモデルにおけるiPSC由来メソアンジオ芽細胞(筋前駆体の一種)の生着および分化を評価するために必要な移植および機能的測定について記述する。
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