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One Minute, Sub-One-Watt Photothermal Tumor ablasjon med Porphysomes, Intrinsic Multifunksjonell Nanovesicles

DOI :

10.3791/50536-v

September 17th, 2013

September 17th, 2013

10,633 Views

1Department of Pharmaceutical Sciences, University of Toronto, 2The Institute of Biomaterials and Biomedical Engineering, University of Toronto, 3Ontario Cancer Institute, Campbell Family Institute For Cancer Research and Techna Institute, 4Department of Biomedical Engineering, University at Buffalo, The State University of New York

Vi utviklet romanen iboende multifunksjonelle nanovesicles kalt porphysomes, som har struktur avhengig fluorescens selvlukkende og unike photothermal egenskaper, og dermed fungere som potente photothermal terapi agenter. Vi formulerte porphysomes bruker høytrykks ekstrudering og undersøkt deres photothermal terapi effekt i en xenograft tumor modell.

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Bioteknologi

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