JoVE Logo
Faculty Resource Center

Sign In

Sensing of Barrier Tissue Disruption with an Organic Electrochemical Transistor

DOI :

10.3791/51102-v

February 10th, 2014

February 10th, 2014

11,482 Views

1Department of Bioelectronics, Ecole Nationale Superieure des Mines, 2Research and Exploratory Development Division, Applied Physics Laboratory, Johns Hopkins University

The Organic Electrochemical Transistor is integrated with live cells and used to monitor ion flux across the gastrointestinal epithelial barrier. In this study, an increase in ion flux, related to disruption of tight junctions, induced by the presence of the calcium chelator EGTA (ethylene glycol-bis(beta-aminoethyl ether)-N,N,N',N'-tetra acetic acid), is measured.

Tags

Keywords Organic Electrochemical Transistor

-- Views

Related Videos

article

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

article

Bacterial Detection & Identification Using Electrochemical Sensors

article

Electric Cell-substrate Impedance Sensing for the Quantification of Endothelial Proliferation, Barrier Function, and Motility

article

Preparation of Silicon Nanowire Field-effect Transistor for Chemical and Biosensing Applications

article

Tissue Engineering by Intrinsic Vascularization in an In Vivo Tissue Engineering Chamber

article

Wet Chemistry and Peptide Immobilization on Polytetrafluoroethylene for Improved Cell-adhesion

article

Development of an Electrochemical DNA Biosensor to Detect a Foodborne Pathogen

article

In Vitro Multiparametric Cellular Analysis by Micro Organic Charge-modulated Field-effect Transistor Arrays

article

Disruption of the Blood-Spinal Cord Barrier Using Low-Intensity Focused Ultrasound in a Rat Model

article

Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks (Video) | JoVE

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved