Name: shrinkage of dental composite in simulated cavity measured with digital image correlation
Uploaded: 2014-07-21T13:00:00
Description: Watch this Scientific Journal Video about Shrinkage of Dental Composite in Simulated Cavity Measured with Digital Image Correlation at JoVE.com

这项研究是由明尼苏达牙科研究中心生物材料与生物力学（MDRCBB）的支持。

注意：使用玻璃腔三牙复合树脂进行了研究：Z100，Z250和LS，如材料清单中列出。其中，LS是已知的以大约1.0％的体积收缩率的低收缩树脂复合材料，比Z250和Z100（〜2％和〜2.5％）18-19的要低得多。的设备和在本研究中使用的其它材料也被在物料列表给出。 1。模型腔准备<ol><li>切一个长圆筒形玻璃棒，直径10毫米，为使用低速金刚石锯片10毫米长的短杆。 </li><li>切近?...

<ol>
	<li>Palin, W. M., Fleming, G. J. P., Nathwani, H., Burke, F. J. T., Randall, R. C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=In+vitro+cuspal+deflection+and+microleakage+of+maxillary+premolars+restored+with+novel+low-shrink+dental+composites.">In vitro cuspal deflection and microleakage of maxillary premolars restored with novel low-shrink dental composites.</a> Dental Materials. 21, 324-335 (2005).</li><li>Li, H., Li, J., Yun, X., Liu, X., Fok, A. S. -. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Non-destructive+examination+of+interfacial+debonding+using+acoustic+emission.">Non-destructive examination of interfacial debonding using acoustic emission.</a> Dental Materials. 27, 964-971 (2011).</li><li>Dijken, J. W., Lindberg, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Clinical+effectiveness+of+a+low-shrinkage+resin+composite:+a+five-year+evaluation.">Clinical effectiveness of a low-shrinkage resin composite: a five-year evaluation.</a> J Adhes Dent. 11, 143-148 (2009).</li><li>Yamazaki, P. C. V., Bedran-Russo, A. K. B., Pereira, P. N. R., Swift, E. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Microleakage+Evaluation+of+a+New+Low-shrinkage+Composite+Restorative+Material.">Microleakage Evaluation of a New Low-shrinkage Composite Restorative Material.</a> Operative Dentistry. 31, 670-676 (2006).</li><li>Watts, D. C., Cash, A. J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Determination+of+polymerization+shrinkage+kinetics+in+visible-light-cured+materials:+methods+development.">Determination of polymerization shrinkage kinetics in visible-light-cured materials: methods development.</a> Dental materials : official publication of the Academy of Dental Materials. 7, 281-287 (1991).</li><li>Gee, A. J., Davidson, C. L., Smith, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+modified+dilatometer+for+continuous+recording+of+volumetric+polymerization+shrinkage+of+composite+restorative+materials.">A modified dilatometer for continuous recording of volumetric polymerization shrinkage of composite restorative materials.</a> Journal of Dentistry. 9, 36-42 (1981).</li><li>Sakaguchi, R. L., Sasik, C. T., Bunczak, M. A., Douglas, W. H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Strain+gauge+method+for+measuring+polymerization+contraction+of+composite+restoratives.">Strain gauge method for measuring polymerization contraction of composite restoratives.</a> Journal of Dentistry. 19, 312-316 (1991).</li><li>Fogleman, E. A., Kelly, M. T., Grubbs, W. T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Laser+interferometric+method+for+measuring+linear+polymerization+shrinkage+in+light+cured+dental+restoratives.">Laser interferometric method for measuring linear polymerization shrinkage in light cured dental restoratives.</a> Dental Materials. 18, 324-330 (2002).</li><li>Arenas, G., Noriega, S., Vallo, C., Duchowicz, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Polymerization+shrinkage+of+a+dental+resin+composite+determined+by+a+fiber+optic+Fizeau+interferometer.">Polymerization shrinkage of a dental resin composite determined by a fiber optic Fizeau interferometer.</a> Optics Communications. 271, 581-586 (2007).</li><li>Demoli, N., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Digital+interferometry+for+measuring+of+the+resin+composite+thickness+variation+during+blue+light+polymerization.">Digital interferometry for measuring of the resin composite thickness variation during blue light polymerization.</a> Optics Communications. 231, 45-51 (2004).</li><li>Sharp, L. J., Choi, I. B., Lee, T. E., Sy, A., Suh, B. I. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Volumetric+shrinkage+of+composites+using+video-imaging.">Volumetric shrinkage of composites using video-imaging.</a> Journal of Dentistry. 31, 97-103 (2003).</li><li>Feilzer, A. J., De Gee, A. J., Davidson, C. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Setting+stress+in+composite+resin+in+relation+to+configuration+of+the+restoration.">Setting stress in composite resin in relation to configuration of the restoration.</a> Journal of Dental Research. 66, 1636-1639 (1987).</li><li>Li, J., Fok, A. S., Satterthwaite, J., Watts, D. C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Measurement+of+the+full-field+polymerization+shrinkage+and+depth+of+cure+of+dental+composites+using+digital+image+correlation.">Measurement of the full-field polymerization shrinkage and depth of cure of dental composites using digital image correlation.</a> Dental Materials. 25, (2009).</li><li>Chuang, S. -. F., Chang, C. -. H., Chen, T. Y. -. F. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Spatially+resolved+assessments+of+composite+shrinkage+in+MOD+restorations+using+a+digital-image-correlation+technique.">Spatially resolved assessments of composite shrinkage in MOD restorations using a digital-image-correlation technique.</a> Dental Materials. 27, 134-143 (2011).</li><li>Arakawa, A., Morita, Y., Uchino, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Polymerization+Shrinkage+Behavior+of+Light+Cure+Resin+Composites+in+Cavities.">Polymerization Shrinkage Behavior of Light Cure Resin Composites in Cavities.</a> Journal of Biomechanical Science and Engineering. 4, 356-364 (2009).</li><li>Lee, M. R., Cho, B. H., Son, H. H., Um, C. M., Lee, I. B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Influence+of+cavity+dimension+and+restoration+methods+on+the+cusp+deflection+of+premolars+in+composite+restoration.">Influence of cavity dimension and restoration methods on the cusp deflection of premolars in composite restoration.</a> Dental Materials. 23, 288-295 (2007).</li><li>Park, J., Chang, J., Ferracane, J., Lee, I. B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=How+should+composite+be+layered+to+reduce+shrinkage+stress:+Incremental+or+bulk+filling.">How should composite be layered to reduce shrinkage stress: Incremental or bulk filling.</a> Dental Materials. 24, 1501-1505 (2008).</li><li>Weinmann, W., Thalacker, C., Guggenberger, R. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Siloranes+in+dental+composites.">Siloranes in dental composites.</a> Dental Materials. 21, 68-74 (2005).</li><li>Silikas, N., Eliades, G., Watts, D. C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Light+intensity+effects+on+resin-composite+degree+of+conversion+and+shrinkage+strain.">Light intensity effects on resin-composite degree of conversion and shrinkage strain.</a> Dental Materials. 16, 292-296 (2000).</li><li>Yaofeng, S., Pang, J. H. L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Study+of+optimal+subset+size+in+digital+image+correlation+of+speckle+pattern+images.">Study of optimal subset size in digital image correlation of speckle pattern images.</a> Optics and Lasers in Engineering. 45, 967-974 (2007).</li><li>Versluis, A., Tantbirojn, D., Pintado, M. R., DeLong, R., Douglas, W. H. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Residual+shrinkage+stress+distributions+in+molars+after+composite+restoration.">Residual shrinkage stress distributions in molars after composite restoration.</a> Dental Materials. 20, 554-564 (2004).</li><li>Sakaguchi, R. L., Wiltbank, B. D., Murchison, C. F. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Prediction+of+composite+elastic+modulus+and+polymerization+shrinkage+by+computational+micromechanics.">Prediction of composite elastic modulus and polymerization shrinkage by computational micromechanics.</a> Dental Materials. 20, 397-401 (2004).</li><li>Lecompte, D., Bossuyt, S., Cooreman, S., Sol, H., Vantomme, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=.">.</a> , (2007).</li><li>Huang, J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Digital+Image+Correlation+with+Self-Adaptive+Gaussian+Windows.">Digital Image Correlation with Self-Adaptive Gaussian Windows.</a> Exp Mech. 53, 505-512 (2013).</li><li>Li, J., Lau, A., Fok, A. S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Application+of+digital+image+correlation+to+full-field+measurement+of+shrinkage+strain+of+dental+composites.">Application of digital image correlation to full-field measurement of shrinkage strain of dental composites.</a> J. Zhejiang Univ. Sci. A. 14, 1-10 (2013).</li></ol>

与收缩应变的测量相同的形状和尺寸中使用玻璃腔是在结果中的变化最小化由于在大小，解剖学和天然人类牙齿材料性质的差异。另外，在本研究中使用的熔凝石英玻璃具有类似的杨氏模量对牙釉质，使其成为一个合适的模拟物材料为天然牙齿只要机械行为方面21-22。虽然在真实牙齿修复体，树脂复合材料主要是结合到牙质，而不是搪瓷，并且有两个牙体组织之间的硬度差，预计不会有较...

树脂基复合材料被广泛使用，因为其卓越的美学和操控性能在口腔修复。然而，尽管被粘结到牙齿组织中的树脂复合材料的聚合收缩仍然是临床关注，开发了收缩应力可能会引起脱粘在牙齿修复接口1 -2。因此，细菌可侵入和驻留在失败的领域，并导致继发龋。另一方面，如果恢复是公粘结到牙齿，收缩应力可能引起牙齿组织开裂。无论这些故障将危及使用寿命的牙修复体，其将受到大量的热负荷和机械负荷的循环。 聚合收缩应变和应力的测量牙科复合树脂3-4的开发和评估也因此成为不可或缺的</SUP&gt;。各种测量技术或方法已被开发5-11以提供一个简单的设置，用于测量的树脂复合材料的收缩行为可靠的主要目的。而它们所提供的测量值可能是足够的，用于比较不同材料的收缩行为，它们不会在收缩应力在实际恢复牙齿哪里如何开发有助于理解。具体地讲，的极大兴趣问题是空心墙如何约束复合材料和导线的收缩在牙齿修复12创造收缩应力。需要注意的是，要创建的收缩应力，树脂复合材料的收缩变形的部分具有被转换成拉伸弹性应变。因此，这将是有用的，如果在恢复的应变的该组件可以被测量。最近，光学全视野应变测量技术，数字图像相关（DIC），已经被应用到自由shrinka的测定在牙科修复13-15的树脂复合材料GE以及物料流。 DIC的基本思想是从它的变形过程中，据此，位移和应变场超过该表面可以被确定拍摄连续图像在样品表面跟踪和关联可见的图案。全视场测量的DIC的方法，该方法是在观察非均匀变形和应变图案13是特别有用的主要优点之一。在这项研究中，DIC是用来揭示的应变模式在牙科复合树脂修复，以了解收缩应力的发展及物色潜在位点剥离的目的。这个信息是不是在上面14-15列举的作品，其中仅测得的修复体的位移，由于聚合收缩直接可用。该测定是使用模拟的牙近中 - 牙合 - 远（MOD）齿腔作为企图复制品的模型进行忒现实牙齿修复的应力或应变。虽然使用真实牙齿更解剖学代表的该缺点是在解剖结构，机械性能，水化程度以及看不见的内部缺陷14的齿之间的显著本质上的差异所导致的大的变化的结果。为了克服这种缺陷，一些研究试图通过将它们分组在颊大小16方面或完全取代了牙齿替代材料17的模型，规范的牙齿样本。例如，铝塑其中有一个类似的杨氏模量，以珐琅（69和83 GPa时，分别）已受聘在收缩应力测量，收缩应力所指出的风口浪尖上偏转17的水平。在这项研究中，石英玻璃的模型（模腔）被用来代替，因为该材料也具有类似的杨氏模量（63 GPa）的对牙釉质和，因为它是透明耳鼻喉科，在标本的任何剥离或开裂可以很容易地观察到。

<table border="0" cellpadding="0" cellspacing="0" width="790">
	<tbody>
		<tr height="42">
			<td height="42" style="height:42px;width:191px;">Dental composite Z100</td>
			<td style="width:167px;">3M ESPE</td>
			<td style="width:175px;">N362979</td>
			<td style="width:259px;">volume shrinkage ~ 2.5%, Young&#39;s modulus ~ 14 GPa</td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:191px;">Dental composite Z250</td>
			<td>3M ESPE</td>
			<td style="width:175px;">N326080</td>
			<td style="width:259px;">volume shrinkage ~ 2.0%, Young&#39;s modulus ~ 11 GPa</td>
		</tr>
		<tr height="42">
			<td height="42" style="height:42px;width:191px;">Dental composite LS</td>
			<td>3M ESPE</td>
			<td style="width:175px;">N240313</td>
			<td style="width:259px;">volume shrinkage ~ 1%, Young&#39;s modulus ~ 10 GPa</td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;">Ceramic Primer</td>
			<td>3M ESPE</td>
			<td style="width:175px;">N167818</td>
			<td style="width:259px;">Rely X</td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;">LS System Adhesive</td>
			<td>3M ESPE</td>
			<td style="width:175px;">N391675</td>
			<td style="width:259px;">Adhesive for compoiste LS</td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;">Adper Single Bond Plus</td>
			<td>3M ESPE</td>
			<td style="width:175px;">501757</td>
			<td style="width:259px;">Adhesive for compoiste Z100 and Z250</td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;">Glass rod&#160;</td>
			<td>Corning Inc.</td>
			<td>&#160;Pyrex 7740 borosilicate&#160;</td>
			<td style="width:259px;"></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:191px;">Curing light&#160;</td>
			<td>3M ESPE</td>
			<td>Elipar S10&#160;</td>
			<td style="width:259px;"></td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:191px;">White paint&#160;</td>
			<td>Krylon Product Group</td>
			<td style="width:175px;"></td>
			<td style="width:259px;">Indoor/Outdoor, Flat white</td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;width:191px;">Charcoal powder&#160;</td>
			<td>Sigma Aldrich, Co.</td>
			<td style="width:175px;">BCBH6518V</td>
			<td style="width:259px;">Fluka activated charcoal</td>
		</tr>
		<tr height="21">
			<td height="21" style="height:21px;">CCD camera&#160;</td>
			<td>Point Grey Research, Inc.</td>
			<td>Point Grey Gras-20S4C-C</td>
			<td style="width:259px;"></td>
		</tr>
	</tbody>
</table>

shrinkage of dental composite in simulated cavity measured with digital image correlation

牙科复合树脂聚合收缩可导致恢复剥离或破裂的牙齿组织中合成，恢复牙齿。为了了解在何处和如何收缩应变和应力的经修复的牙齿发展，数字图像相关（DIC）是用来提供模型修复中的位移和应变分布是经历了聚合收缩的全面视图。 标本与模型腔进行了圆柱形玻璃棒与直径和长度为10毫米制成。近中牙合 - 远（MOD）在每个试样制备腔体的尺寸测量，在3毫米和2毫米的宽度和深度分别。用复合树脂充填型腔后，在观察的表面喷上首次一层薄薄的白色油漆，然后细黑木炭粉打造高对比度的斑点。固化后与之前5分钟，然后拍摄的照片的表面。网络连接应受，这两个图片是使用DIC的软件来计算位移和应变分布相关。 的树脂复合垂直缩水朝向空腔的底部，与具有最大向下位移的恢复的顶部中心部分。在同一时间，它收缩水平朝向其垂直中线。复合材料的收缩率拉伸的材料，在“牙齿修复”界面附近，导致周围的复原牙尖挠度和高的拉伸应变。材料靠近腔壁或地板大都在垂直于界面的方向有直接的菌株。两个直接应变分量的求和表明围绕恢复相对均匀的分布，其大小等于约到的材料的体积收缩应变。

三个试样进行了测试的每种材料。每次试验后，试样进行了检查眼睛或，如果需要，使用显微镜。在“牙齿修复”界面或裂缝没有明显的剥离被发现。 图片的分辨率为1,600×1,180像素，5.8毫米的像素大小。具有32个像素的子集的窗口的大小，位移分布的空间分辨率约为186毫米。 图3显示了固化的修复与Z250制成的位移矢量的典型曲线图。标本与?...

Watch this Scientific Journal Video about Shrinkage of Dental Composite in Simulated Cavity Measured with Digital Image Correlation at JoVE.com

Shrinkage of Dental Composite in Simulated Cavity Measured with Digital Image Correlation

为了了解聚合收缩应力的牙科树脂的复合树脂修复的空间发展，数字图像相关被用于通过关联聚合前后所采取的恢复的图像，以提供恢复的模型玻璃腔的全视野的位移/应变测量。

牙科复合材料在模拟腔收缩测量与数字图像相关

Polymerization shrinkage of dental resin composites can lead to restoration debonding or cracked tooth tissues in composite-restored teeth. In order to ...

Research

JoVE Journal

Medicine

Stem Cell Transplantation in an in vitro Simulated Ischemia/Reperfusion Model

Stem Cell Transplantation in an in vitro Simulated Ischemia/Reperfusion Model

在干细胞移植在体外模拟缺血/再灌注模型

Stem cell transplantation protocols are finding their way into clinical practice1,2,3. Getting better results, making the protocols more robust, and ...

科研

医学

Orthotopic Hind Limb Transplantation in the Mouse

原位后肢移植中的鼠标

In vivo animal model systems, and in particular mouse models, have evolved into powerful and versatile scientific tools indispensable to basic and ...

Electrophysiological Assessment of Murine Atria with High-Resolution Optical Mapping

高分辨率光学制图对小鼠心房电生理的评价

Recent genome-wide association studies targeting atrial fibrillation (AF) have indicated a strong association between the genotype and ...

Contractions of Human-iPSC-derived Cardiomyocyte Syncytia Measured with a Ca-sensitive Fluorescent Dye in Temperature-controlled 384-well Plates

温度控制384孔板中用 Ca 敏感荧光染料测定人 iPSC 的心肌细胞较多的收缩

Spontaneously contracting syncytia of cardiomyocytes derived from human-induced pluripotent stem cells (hiPSC-CM) are a useful model of human cardiac ...

Digital Handwriting Analysis of Characters in Chinese Patients with Mild Cognitive Impairment

中国轻度认知障碍患者人物数字笔迹分析

An increasing amount of evidence shows that cognitive deficits and movement dysfunctions are not separated. Patients with mild cognitive impairment (MCI) ...

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

评估毛细血管和其他血管对光学相干断层扫描血管造影测量的黄斑灌注密度的贡献

Parafoveal circulation of the superficial retinal capillary plexus is usually measured with vessel density, which determines the length of capillaries ...

A Standardized Approach to Extra-Oral and Intra-Oral Digital Photography

口腔外和口腔内数码摄影的标准化方法

Contemporary dentistry mandates a more comprehensive and personalized analysis of each patient. Technological advances in digital photography have played ...

Detection and Removal of Tooth-Colored Composite Resin Using the Fluorescence-Aided Identification Technique

使用荧光辅助识别技术检测和去除牙齿颜色的复合树脂

The detection and removal of tooth-colored filling materials is a major challenge for every dentist. The Fluorescence-aided Identification Technique (FIT) ...

Dynamic Navigation in Endodontics: Guided Access Cavity Preparation by Means of a Miniaturized Navigation System

In the case of teeth with pulp canal calcification (PCC) and apical pathology or pulpitis, root canal treatment can be very challenging. PCC are common ...

Capturing Oral Submucous Fibrosis Tissue Samples for Spatial-Omics Analysis

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection

Unlocking the Mysteries of Oral Potential Malignancies (Video) | JoVE

激光捕获显微切割从口腔粘膜下纤维化样本中分离具有形态学和空间信息的细胞

Oral submucous fibrosis (OSF) is a common type of potentially malignant disorder in the oral cavity. The atrophy of epithelium and fibrosis of the lamina ...