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79.6K Views
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08:03 min
April 15th, 2014
DOI :
10.3791/51275-v
Chapters
0:05
Title
1:51
Preparation of MOG35-55 Emulsion
4:19
Preparation of Pertussis Toxin
5:03
Animal Immunization
6:14
EAE Monitoring
7:04
Results: EAE Symptoms After Immunization
7:29
Conclusion
Summary
实验性自身免疫性脑脊髓炎(EAE)是多发性硬化的一个建立的动物模型。 C57BL / 6小鼠用髓鞘少突胶质细胞糖蛋白(MOG)肽35-55(MOG 35-55),因此所造成的自身反应性免疫细胞,在中枢神经系统中的上行弛缓性麻痹。协议对疾病的诱导和监控将被讨论。
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