Stefan Bittner

Department of Neurology, University of Münster

Affiliated withUniversity of Münster Interdisciplinary Center for Clinical Research (IZKF), Münster Interdisciplinary Center for Clinical Research (IZKF) Münster

Research Area

Immunology and InfectionNeuroscience

Biography

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title	2014
Publication title	2014
Publication title	2015

Other Publications

Article	Year
The two-pore domain potassium channel TASK3 functionally impacts glioma cell death. Journal of neuro-oncology\| PubMed ID: 18217213	2008
TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 critically influence T lymphocyte effector functions. The Journal of biological chemistry\| PubMed ID: 18375952	2008
A beta-lactam antibiotic dampens excitotoxic inflammatory CNS damage in a mouse model of multiple sclerosis. PloS one\| PubMed ID: 18773080	2008
Altered neuronal expression of TASK1 and TASK3 potassium channels in rodent and human autoimmune CNS inflammation. Neuroscience letters\| PubMed ID: 18824070	2008
The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice. Neurobiology of disease\| PubMed ID: 18930826	2009
TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system. Brain : a journal of neurology\| PubMed ID: 19570851	2009
Comment on "Functional consequences of Kv1.3 ion channel rearrangement into the immunological synapse". Immunology letters\| PubMed ID: 19595706	2009
Collateral neuronal apoptosis in CNS gray matter during an oligodendrocyte-directed CD8(+) T cell attack. Glia\| PubMed ID: 19780193	2010
Cytotoxic CD8+ T cell-neuron interactions: perforin-dependent electrical silencing precedes but is not causally linked to neuronal cell death. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20007464	2009
Stromal interaction molecules 1 and 2 are key regulators of autoreactive T cell activation in murine autoimmune central nervous system inflammation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20028655	2010
Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis. Brain : a journal of neurology\| PubMed ID: 20354004	2010
From the background to the spotlight: TASK channels in pathological conditions. Brain pathology (Zurich, Switzerland)\| PubMed ID: 20529081	2010
Upregulation of K2P5.1 potassium channels in multiple sclerosis. Annals of neurology\| PubMed ID: 20582984	2010
Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of immunomodulatory treatment strategies. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy\| PubMed ID: 20623991	2010
Two pore domain potassium channels in cerebral ischemia: a focus on K2P9.1 (TASK3, KCNK9). Experimental & translational stroke medicine\| PubMed ID: 20646278	2010
Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of neuroprotective and alternative treatment strategies. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy\| PubMed ID: 20795753	2010
Glatiramer acetate attenuates pro-inflammatory T cell responses but does not directly protect neurons from inflammatory cell death. The American journal of pathology\| PubMed ID: 21037084	2010
Natalizumab restores evoked potential abnormalities in patients with relapsing-remitting multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England)\| PubMed ID: 21135021	2011
Active immunization with proteolipid protein (190-209) induces ascending paralysing experimental autoimmune encephalomyelitis in C3H/HeJ mice. Journal of immunological methods\| PubMed ID: 21199659	2011
Blockade of the kinin receptor B1 protects from autoimmune CNS disease by reducing leukocyte trafficking. Journal of autoimmunity\| PubMed ID: 21216565	2011
Expression of K2P5.1 potassium channels on CD4+ T lymphocytes correlates with disease activity in rheumatoid arthritis patients. Arthritis research & therapy\| PubMed ID: 21314928	2011
Ion channels in autoimmune neurodegeneration. FEBS letters\| PubMed ID: 21501610	2011
Volume regulation of murine T lymphocytes relies on voltage-dependent and two-pore domain potassium channels. Biochimica et biophysica acta\| PubMed ID: 21575593	2011
IL-17 silencing does not protect nonobese diabetic mice from autoimmune diabetes. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22116823	2012
CD4(+) CD25(+) FoxP3(+) regulatory T cells suppress cytotoxicity of CD8(+) effector T cells: implications for their capacity to limit inflammatory central nervous system damage at the parenc... Journal of neuroinflammation\| PubMed ID: 22373353	2012
The TASK1 channel inhibitor A293 shows efficacy in a mouse model of multiple sclerosis. Experimental neurology\| PubMed ID: 22960185	2012
Identification of two-pore domain potassium channels as potent modulators of osmotic volume regulation in human T lymphocytes. Biochimica et biophysica acta\| PubMed ID: 23041580	2013
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature. Blood\| PubMed ID: 23160472	2013
Correction: Two pore domain potassium channels in cerebral ischemia: a focus on K2P9.1 (TASK3, KCNK9). Experimental & translational stroke medicine\| PubMed ID: 23374257	2013
4-Aminopyridine ameliorates mobility but not disease course in an animal model of multiple sclerosis. Experimental neurology\| PubMed ID: 23748135	2013
Rasmussen encephalitis treated with natalizumab. Neurology\| PubMed ID: 23794679	2013
Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS. Nature medicine\| PubMed ID: 23933981	2013
Protein kinase Cβ as a therapeutic target stabilizing blood-brain barrier disruption in experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23959874	2013
Targeting ion channels for the treatment of autoimmune neuroinflammation. Therapeutic advances in neurological disorders\| PubMed ID: 23997817	2013
Excitotoxic neuronal cell death during an oligodendrocyte-directed CD8+ T cell attack in the CNS gray matter. Journal of neuroinflammation\| PubMed ID: 24093512	2013
A splice variant of the two-pore domain potassium channel TREK-1 with only one pore domain reduces the surface expression of full-length TREK-1 channels. Pflugers Archiv : European journal of physiology\| PubMed ID: 24196565	2013
CD4+NKG2D+ T cells exhibit enhanced migratory and encephalitogenic properties in neuroinflammation. PloS one\| PubMed ID: 24282598	2013
Evans syndrome associated with sterile inflammation of the central nervous system: a case report. Journal of medical case reports\| PubMed ID: 24299473	2013
Ischemia-induced cell depolarization: does the hyperpolarization-activated cation channel HCN2 affect the outcome after stroke in mice? Experimental & translational stroke medicine\| PubMed ID: 24373160	2013
TREK-King the Blood-Brain-Barrier. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology\| PubMed ID: 24557892	2014
Blocking of α4 integrin does not protect from acute ischemic stroke in mice. Stroke; a journal of cerebral circulation\| PubMed ID: 24743435	2014
Human CD4+ HLA-G+ regulatory T cells are potent suppressors of graft-versus-host disease in vivo. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 24744146	2014
Phospholipase D1 mediates lymphocyte adhesion and migration in experimental autoimmune encephalomyelitis. European journal of immunology\| PubMed ID: 24811005	2014
Effects of glatiramer acetate in a spontaneous model of autoimmune neuroinflammation. The American journal of pathology\| PubMed ID: 24819960	2014
Three-dimensional organic microlasers with low lasing thresholds fabricated by multiphoton and UV lithography. Optics express\| PubMed ID: 24921350	2014
Transient receptor potential melastatin subfamily member 2 cation channel regulates detrimental immune cell invasion in ischemic stroke. Stroke; a journal of cerebral circulation\| PubMed ID: 25236871	2014
The two-pore domain potassium channel KCNK5 deteriorates outcome in ischemic neurodegeneration. Pflugers Archiv : European journal of physiology\| PubMed ID: 25315980	2014
The CNS under pathophysiologic attack-examining the role of K2P channels. Pflugers Archiv : European journal of physiology\| PubMed ID: 25482672	2014
Long-term efficacy of alemtuzumab in polymyositis. Rheumatology (Oxford, England)\| PubMed ID: 25552256	2014