Monitoramento Funcionalidade e Morfologia da vasculatura Recrutado por fatores secretados por geradores de Células Tumorais de crescimento rápido

We describe a matrigel plug assay to illustrate angiogenic potential of a pool of factors secreted by cancer cells using two complementary imaging modalities, ultrasound and endomicroscopy. The matrigel, an extracellular matrix (ECM)-mimic gel, is utilized to introduce the host (mouse) with angiogenic factors secreted to the conditioned media (C.M.).