JoVE Logo
Faculty Resource Center

Sign In

Yöntem Yanıcı Tütün Ürün Müstahzarların Sitotoksisite ve immünosupresyonun değerlendirin

DOI :

10.3791/52351-v

January 10th, 2015

January 10th, 2015

11,304 Views

1Department of Microbiology and Immunology, Wake Forest University Health Sciences, 2R&D Department, R.J. Reynolds Tobacco Company

Using optimized human peripheral blood mononuclear cell (PBMC) ex vivo assays, we showed that a combustible tobacco product preparation markedly suppresses receptor-mediated intracellularly secreted cytokines and cytolytic ability of effector PBMCs. These rapid assays may be useful in product evaluation and understanding the potential long-term effects of tobacco exposure.

Tags

Immunology

-- Views

Related Videos

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved