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Detection of Exosomal Biomarker by Electric Field-induced Release and Measurement (EFIRM)

DOI :

10.3791/52439-v

January 23rd, 2015

January 23rd, 2015

18,244 Views

1School of Dentistry, University of California, Los Angeles, 2School of Medicine, Clinical Nutrition, University of California, Los Angeles

Exosomes are microvesicular structures found within biofluids that potentially carry important disease discriminatory biomarkers. Here, a novel method is used to specifically extract exosomes and rapidly test the exosomal cargo for both RNA/protein targets following the disruption of exosomes using non-uniform electric cyclic square waves.

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Keywords Exosomes

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