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Mosaic Zebrafish genmodifiering för Funktionell Genomic analys av kandidat Kooperativa gener i tumör Patogenes

DOI :

10.3791/52567-v

March 31st, 2015

March 31st, 2015

10,944 Views

1Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic College of Medicine, Center for Individualized Medicine, 2Tufts University School of Medicine, 3Department of Biochemistry and Molecular Biology, Mayo Clinic

The goal of this study is to demonstrate how the mosaic transgenesis strategy can be used in zebrafish to rapidly and efficiently assess the relative contributions of multiple oncogenes in tumor initiation and progression in vivo.

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Utvecklingsbiologi

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