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DOI :
10.3791/52879-v
•
8:46 min
December 9th, 2015
Chapters
0:05
Title
1:01
Assessing GI50 for Compounds of Interest and Setting up Drug Resistance Assays
4:27
Isolating Single Cell Clones
6:37
Results: Assessment of Drug Resistance
8:06
Conclusion
前または臨床的発症次 - - 標的治療に対する薬剤耐性は広範囲に及び抵抗のメカニズムを同定することが必要である代替臨床管理戦略を導くために重要です。ここでは、これらのメカニズムの発見を促進するためにシークエンシングを用いたin vitro での薬剤耐性株のカップルの導出にプロトコルを提示します。
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