Sign In

An Introduction to Molecular Developmental Biology

Overview

Molecular signals play a major role in the complex processes occurring during embryonic development. These signals regulate activities such as cell differentiation and migration, which contribute to the formation of specific cell types and structures. The use of molecular approaches allows researchers to investigate these physical and chemical mechanisms in detail.

This video will review a brief history of the study of molecular events during development. Next, key questions asked by molecular developmental biologists today will be reviewed, followed by a discussion of several prominent methods used to answer these questions, such as staining, explant culture, and live-cell imaging. Finally, we will look at some current applications of these techniques to the study of developmental biology.

Procedure

Studies in the field of molecular developmental biology provide insight about the changes that occur at the cellular level during differentiation and development. Researchers examine the physical and chemical mechanisms that regulate cell functions. This helps in understanding how cells give rise to specialized tissues within the maturing embryo, and how defects at the molecular level can lead to disease states.

This video presents a brief history of molecular developmental biology, introduces key questions asked

Log in or to access full content. Learn more about your institution’s access to JoVE content here

Tags
Molecular Developmental BiologyCellular LevelDifferentiationDevelopmentPhysical MechanismsChemical MechanismsCell FunctionsSpecialized TissuesEmbryoDefectsDisease StatesLandmark StudiesConrad WaddingtonCell FateConceptual ModelEpigenetic LandscapeRita Levi MontalciniStanley CohenTransplanting TumorsChick EmbryosNeuron Growth

Skip to...

0:00

Overview

0:52

Historical Highlights

3:53

Key Questions

5:16

Prominent Methods

7:13

Applications

8:56

Summary

Videos from this collection:

article

Now Playing

An Introduction to Molecular Developmental Biology

Developmental Biology

29.4K Views

article

An Introduction to Developmental Genetics

Developmental Biology

35.2K Views

article

Gene Silencing with Morpholinos

Developmental Biology

31.9K Views

article

Genetic Engineering of Model Organisms

Developmental Biology

19.1K Views

article

Explant Culture for Developmental Studies

Developmental Biology

23.3K Views

article

Whole-Mount <em>In Situ</em> Hybridization

Developmental Biology

63.2K Views

article

An Introduction to Stem Cell Biology

Developmental Biology

33.3K Views

article

Embryonic Stem Cell Culture and Differentiation

Developmental Biology

34.0K Views

article

Induced Pluripotency

Developmental Biology

25.4K Views

article

An Introduction to Organogenesis

Developmental Biology

33.3K Views

article

Fate Mapping

Developmental Biology

59.7K Views

article

Transplantation Studies

Developmental Biology

8.2K Views

article

An Introduction to Aging and Regeneration

Developmental Biology

13.8K Views

article

Invertebrate Lifespan Quantification

Developmental Biology

6.0K Views

article

Tissue Regeneration with Somatic Stem Cells

Developmental Biology

20.3K Views

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2025 MyJoVE Corporation. All rights reserved